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How to get fromLancaster to Columbiaby plane, train (Amtrak), bus (Greyhound, Flixbus), car, train, subway, or bus

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There are 8 ways to get from Lancaster to Columbia by plane, train (Amtrak), bus (Greyhound, Flixbus), car, train, subway, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Harrisburg International Airport

    best
    1. Fly from Harrisburg International Airport (MDT) to Columbia (CAE)plane plane MDT - CAE
    9h 16m
    $68–365

  2. Train (Amtrak)

    1. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to Washington Union Stationtrain train
    3. Take the train from Washington Union Station to Columbia Stationtrain train
    17h 18m
    $207–1,046

  3. Bus

    1. Take the bus from Harrisburg Bus Station to Washington Union Stationbus bus
    2. Take the bus from Washington Union Station to Raleigh Bus Stationbus bus
    3. Take the bus from Raleigh Bus Station to Sumter Bus Stopbus bus
    4. Take the bus from James E Clyburn Intermodal Transportation Center to Assembly Senate Northbus bus 44
    20h 5m
    $87–178

  4. Drive 570.6 mi

    1. Drive from Lancaster to Columbiacar car 570.6 mi
    10h 45m
    $105–151

  5. Train to Philadelphia International Airport, fly

    1. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Columbia (CAE)plane plane PHL - CAE
    8h 33m
    $112–541

  6. Train, train to Ronald Reagan Washington National Airport, fly

    1. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to Washington Union Stationtrain train
    3. Fly from Ronald Reagan Washington National Airport (DCA) to Columbia (CAE)plane plane DCA - CAE
    10h 8m
    $153–1,265

  7. Train, subway to Washington Dulles International Airport, fly

    1. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to Washington Union Stationtrain train
    3. Take the subway from Farragut West, Blue/Orange/Silver Line Track 2 Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    4. Fly from Washington Dulles International Airport (IAD) to Columbia (CAE)plane plane IAD - CAE
    10h 43m
    $113–1,044

  8. Bus, train

    1. Take the bus from Harrisburg Bus Station to Washington Union Stationbus bus Greyhound US0430
    2. Take the train from Washington Union Station to Columbia Stationtrain train Floridian
    18h 11m
    $172–386

Lancaster to Columbia by bus and train (Amtrak)

Calendar7Weekly Services
Duration17h 18mAverage Duration
Ticket$207Cheapest Price
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Questions & Answers

Map of how to get from Lancaster to Columbia.ExpandLaunch map view
  • Distance: 553.2 mi
  • Duration: 9h 16m

What companies run services between Lancaster, PA, USA and Columbia, SC, USA?

United Airlines, American Airlines, and Delta fly from Harrisburg International Airport (MDT) to Columbia (CAE) hourly. Alternatively, you can take a bus from W. Walnut & N. Mary St. to Columbia Station via AMTRAK ETown, Elizabethtown Amtrak Station, 30th Street Station, and Washington Union Station in around 17h 18m.

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