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How to get fromLancaster to Great Smoky Mountainsby train, plane, car, bus, or subway

Find Transport to Great Smoky Mountains

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There are 12 ways to get from Lancaster to Great Smoky Mountains by train, plane, car, bus, or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Philadelphia International Airport, fly to Mcghee Tyson Airport, drive

    best
    1. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Mcghee Tyson Airport (TYS)plane plane PHL - TYS
    3. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    8h 59m
    $199–1,024

  2. Drive 577.9 mi

    cheapest
    1. Drive from Lancaster to Great Smoky Mountainscar car 577.9 mi
    10h 54m
    $106–153

  3. Train, bus, drive via Greensboro

    1. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to Greensborotrain train
    3. Take the bus from Greensboro Bus Stop to Asheville, NCbus bus
    4. Drive from Asheville, NC to Great Smoky Mountainscar car
    19h 31m
    $184–395

  4. Train, bus, drive

    1. Take the train from Elizabethtown Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the bus from New York to Knoxvillebus bus Nyc
    3. Drive from Knoxville to Great Smoky Mountainscar car
    20h 36m
    $165–276

  5. Train to Philadelphia International Airport, fly to Asheville Regional Airport, drive

    1. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Asheville Regional Airport (AVL)plane plane PHL - AVL
    3. Drive from Asheville-Airport-AVL to Great Smoky Mountainscar car
    9h 15m
    $123–550

  6. Train, train to Baltimore-Washington International Airport, fly to Mcghee Tyson Airport, drive

    1. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to BWI Thurgood Marshalltrain train
    3. Fly from Baltimore-Washington International Airport (BWI) to Mcghee Tyson Airport (TYS)plane plane BWI - TYS
    4. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    9h 58m
    $190–1,521

  7. Train, train to Ronald Reagan Washington National Airport, fly to Mcghee Tyson Airport, drive

    1. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to Washington Union Stationtrain train
    3. Fly from Ronald Reagan Washington National Airport (DCA) to Mcghee Tyson Airport (TYS)plane plane DCA - TYS
    4. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    10h 48m
    $250–1,828

  8. Train, train to Ronald Reagan Washington National Airport, fly to Asheville Regional Airport, drive

    1. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to Washington Union Stationtrain train
    3. Fly from Ronald Reagan Washington National Airport (DCA) to Asheville Regional Airport (AVL)plane plane DCA - AVL
    4. Drive from Asheville-Airport-AVL to Great Smoky Mountainscar car
    10h 46m
    $159–1,284

  9. Train, subway to Washington Dulles International Airport, fly to Mcghee Tyson Airport, drive

    1. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to Washington Union Stationtrain train
    3. Take the subway from Farragut West, Blue/Orange/Silver Line Track 2 Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    4. Fly from Washington Dulles International Airport (IAD) to Mcghee Tyson Airport (TYS)plane plane IAD - TYS
    5. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    11h 14m
    $170–1,377

  10. Train, train to Baltimore-Washington International Airport, fly to Greenville–Spartanburg International Airport, drive

    1. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to BWI Thurgood Marshalltrain train
    3. Fly from Baltimore-Washington International Airport (BWI) to Greenville–Spartanburg International Airport (GSP)plane plane BWI - GSP
    4. Drive from Greenville–Spartanburg International Airport (GSP) to Great Smoky Mountainscar car
    11h 5m
    $169–1,340

  11. Train, bus, drive #2

    1. Take the train from Elizabethtown Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    3. Drive from Knoxville, TN to Great Smoky Mountainscar car
    20h 40m
    $164–244

  12. Bus, drive

    1. Take the bus from Harrisburg Bus Station to New York City Chinatownbus bus
    2. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    3. Drive from Knoxville, TN to Great Smoky Mountainscar car
    23h 4m
    $142–194

Philadelphia International Airport (PHL) to Mcghee Tyson Airport (TYS) flights

Calendar67Weekly Planes
Duration3h 32mAverage Duration
Ticket$169Cheapest Price
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Questions & Answers

Map of how to get from Lancaster to Great Smoky Mountains.ExpandLaunch map view
  • Distance: 728.3 mi
  • Duration: 8h 59m

What companies run services between Lancaster, PA, USA and Great Smoky Mountains, TN, USA?

There is no direct connection from Lancaster to Great Smoky Mountains. However, you can take the line 18 bus to AMTRAK ETown, walk to Elizabethtown Amtrak Station, take the train to 30th Street Station, take the train to Airport Terminal A, walk to Philadelphia International Airport (PHL) airport, fly to Mcghee Tyson Airport (TYS), then drive to Great Smoky Mountains. Alternatively, you can take a bus from W. Walnut & N. Mary St. to Great Smoky Mountains via AMTRAK ETown, Elizabethtown Amtrak Station, 30th Street Station, Greensboro, Greensboro Bus Stop, and Asheville, NC in around 19h 31m.

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