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How to get fromLancaster to Hartsvilleby train, plane, car, bus (Greyhound, Flixbus), train (Amtrak), bus, or taxi

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There are 9 ways to get from Lancaster to Hartsville by train, plane, car, bus (Greyhound, Flixbus), train (Amtrak), bus, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Philadelphia International Airport, fly to Myrtle Beach, drive

    best
    1. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Myrtle Beach (MYR)plane plane PHL - MYR
    3. Drive from Myrtle Beach (MYR) to Hartsvillecar car
    9h 4m
    $116–503

  2. Drive 509.4 mi

    cheapest
    1. Drive from Lancaster to Hartsvillecar car 509.4 mi
    9h 52m
    $93–135

  3. Bus

    1. Take the bus from Harrisburg Bus Station to Baltimore Downtown Bus Stationbus bus Greyhound US0430
    2. Take the bus from Baltimore Downtown Bus Station to Florencebus bus FlixBus N2472
    15h 48m
    $146–229

  4. Train (Amtrak)

    1. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train Keystone Service / ...
    2. Take the train from 30th Street Station to Florence Stationtrain train Palmetto / ...
    18h 12m
    $272–506

  5. Fly Harrisburg International Airport to Charlotte Douglas International Airport, bus, taxi

    1. Fly from Harrisburg International Airport (MDT) to Charlotte Douglas International Airport (CLT)plane plane MDT - CLT
    2. Take the bus from Charlotte Bus Station to Camdenbus bus
    3. Take the taxi from Camden to Hartsvilletaxi taxi
    10h 13m
    $311–1,292

  6. Train, train to Baltimore-Washington International Airport, fly to Myrtle Beach, drive

    1. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to BWI Thurgood Marshalltrain train
    3. Fly from Baltimore-Washington International Airport (BWI) to Myrtle Beach (MYR)plane plane BWI - MYR
    4. Drive from Myrtle Beach (MYR) to Hartsvillecar car
    10h
    $307–1,380

  7. Train to Philadelphia International Airport, fly to Charlotte Douglas International Airport, bus, taxi

    1. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Charlotte Douglas International Airport (CLT)plane plane PHL - CLT
    3. Take the bus from Charlotte Bus Station to Camdenbus bus
    4. Take the taxi from Camden to Hartsvilletaxi taxi
    11h 3m
    $275–428

  8. Train to Philadelphia International Airport, fly to Columbia, bus, taxi

    1. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Columbia (CAE)plane plane PHL - CAE
    3. Take the bus from Columbia, SC to Camdenbus bus
    4. Take the taxi from Camden to Hartsvilletaxi taxi
    11h 56m
    $402–1,553

  9. Bus via Richmond

    1. Take the bus from Harrisburg Bus Station to Washington Union Stationbus bus
    2. Take the bus from Washington Union Station to Richmondbus bus
    3. Take the bus from Richmond - Brook + Walmart Nhood Mkt to Florence, SCbus bus Nyc
    17h 18m
    $153–236

Philadelphia International Airport (PHL) to Myrtle Beach (MYR) flights

Calendar42Weekly Planes
Duration2h 49mAverage Duration
Ticket$73Cheapest Price
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Questions & Answers

Map of how to get from Lancaster to Hartsville.ExpandLaunch map view
  • Distance: 679.9 mi
  • Duration: 9h 4m

What companies run services between Lancaster, PA, USA and Hartsville, SC, USA?

You can take a bus from Queen St. Station to Hartsville via AMTRAK ETown, Elizabethtown Amtrak Station, Harrisburg, Harrisburg Bus Station, Baltimore Downtown Bus Station, and Florence in around 15h 48m. Alternatively, you can take a bus from W. Walnut & N. Mary St. to Hartsville via AMTRAK ETown, Elizabethtown Amtrak Station, 30th Street Station, and Florence Station in around 18h 12m.

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