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How to get fromLancaster to Iowaby plane, bus (Flixbus, Greyhound), train, bus, car, or bus (Greyhound)

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There are 8 ways to get from Lancaster to Iowa by plane, bus (Flixbus, Greyhound), train, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Lancaster to Quad City International Airport

    best
    1. Fly from Lancaster (LNS) to Quad City International Airport (MLI)plane plane LNS - MLI
    7h 41m
    $79–404

  2. Bus

    1. Take the bus from Harrisburg Bus Station to Chicago Bus Stationbus bus FlixBus N2640 / ...
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    27h 25m
    $192–294

  3. Train, bus via Pittsburgh

    1. Take the train from Elizabethtown Amtrak Station to Pittsburgh Amtrak Stationtrain train
    2. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    4. Take the bus from Galesburg to Des Moinesbus bus
    28h 21m
    $532–837

  4. Drive  1,007.2 mi

    1. Drive from Lancaster to Des Moinescar car 1,007.2 mi
    16h 37m
    $184–266

  5. Train to Philadelphia International Airport, fly to Des Moines

    1. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Des Moines (DSM)plane plane PHL - DSM
    8h 17m
    $177–699

  6. Train to Philadelphia International Airport, fly to Omaha

    1. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Omaha (OMA)plane plane PHL - OMA
    8h 39m
    $234–906

  7. Bus via Indianapolis (Greyhound)

    1. Take the bus from Harrisburg Bus Station to Indianapolis Union Stationbus bus Greyhound US0421
    2. Take the bus from Indianapolis Union Station to Des Moinesbus bus Greyhound US0157S
    27h 35m
    $192–294

  8. Train, bus

    1. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    39h 22m
    $660–1,072

Lancaster (LNS) to Quad City International Airport (MLI) flights

Calendar11Weekly Planes
Duration5h 54mAverage Duration
Ticket$77Cheapest Price
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Comparing Your Travel Options

Map of how to get from Lancaster to Iowa.ExpandLaunch map view
  • Distance: 764.2 mi
  • Duration: 7h 41m

What companies run services between Lancaster, PA, USA and Iowa, USA?

United Airlines flies from Lancaster (LNS) to Quad City International Airport (MLI) twice daily. Alternatively, you can take a bus from Queen St. Station to Des Moines via AMTRAK ETown, Elizabethtown Amtrak Station, Harrisburg, Harrisburg Bus Station, Chicago Bus Station, and Des Moines in around 27h 25m.

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