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How to get fromLancaster to Jefferson Cityby plane, bus, train, train (Amtrak), or car

Find Transport to Jefferson City

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There are 5 ways to get from Lancaster to Jefferson City by plane, bus, train, train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Lancaster

    best
    1. Fly from Lancaster (LNS) to Columbia Regional Airport (COU)plane plane LNS - COU
    9h 12m
    $181–540

  2. Bus, train

    cheapest
    1. Take the bus from Harrisburg Bus Station to St Louis Bus Stationbus bus Greyhound US0421
    2. Take the train from St. Louis to Jefferson City Stationtrain train Missouri River Runner / ...
    24h 49m
    $160–321

  3. Train (Amtrak)

    1. Take the train from Elizabethtown Amtrak Station to Pittsburgh Amtrak Stationtrain train
    2. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Jefferson City Stationtrain train
    27h 31m
    $353–762

  4. Drive 936.7 mi

    1. Drive from Lancaster to Jefferson Citycar car 936.7 mi
    16h 12m
    $171–247

  5. Fly from Harrisburg International Airport

    1. Fly from Harrisburg International Airport (MDT) to Columbia Regional Airport (COU)plane plane MDT - COU
    9h 32m
    $276–1,023

Lancaster to Jefferson City by bus and train

Calendar14Weekly Services
Duration24h 49mAverage Duration
Ticket$160Cheapest Price
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Questions & Answers

Map of how to get from Lancaster to Jefferson City.ExpandLaunch map view
  • Distance: 881.5 mi
  • Duration: 9h 12m

What companies run services between Lancaster, PA, USA and Jefferson City, MO, USA?

United Airlines flies from Lancaster (LNS) to Columbia Regional Airport (COU) twice daily. Alternatively, you can take a bus from W. Walnut & N. Mary St. to Jefferson City Station via AMTRAK ETown, Elizabethtown Amtrak Station, Pittsburgh Amtrak Station, and Chicago Union Station in around 27h 31m.

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