There are 9 ways to get from Lancaster to Key West by plane, bus (Greyhound, Flixbus), train, bus, car, or subway
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Harrisburg International Airport
best- Fly from Harrisburg International Airport (MDT) to Key West International Airport (EYW)plane MDT - EYW
9h 14m$96–409Bus
- Take the bus from Harrisburg Bus Station to Washington Union Stationbus
- Take the bus from Washington Union Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
35h 16m$223–343Train, bus
- Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain
- Take the train from 30th Street Station to Fort Lauderdale Amtrak Stationtrain
- Take the train from Fort Lauderdale Station to Miami Airport Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
38h 35m$775–1,217Drive 1,310.9 mi
- Drive from Lancaster to Key Westcar 1,310.9 mi
23h 16m$240–346Train to Philadelphia International Airport, fly
- Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain
- Fly from Philadelphia International Airport (PHL) to Key West International Airport (EYW)plane PHL - EYW
8h 30m$170–639Train, train to Ronald Reagan Washington National Airport, fly
- Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain
- Take the train from 30th Street Station to Washington Union Stationtrain
- Fly from Ronald Reagan Washington National Airport (DCA) to Key West International Airport (EYW)plane DCA - EYW
10h 25m$202–1,342Train, train to Baltimore-Washington International Airport, fly
- Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain
- Take the train from 30th Street Station to BWI Thurgood Marshalltrain
- Fly from Baltimore-Washington International Airport (BWI) to Key West International Airport (EYW)plane BWI - EYW
11h 10m$177–1,205Train, train to Newark Liberty International Airport, fly
- Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain
- Take the train from 30th Street Station to Newark Liberty International Airporttrain
- Fly from Newark Liberty International Airport (EWR) to Key West International Airport (EYW)plane EWR - EYW
10h 12m$183–585Train, subway to Washington Dulles International Airport, fly
- Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain
- Take the train from 30th Street Station to Washington Union Stationtrain
- Take the subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway
- Fly from Washington Dulles International Airport (IAD) to Key West International Airport (EYW)plane IAD - EYW
11h 2m$167–1,121
Lancaster to Key West by bus, train, and foot
Comparing Your Travel Options
The cheapest way to get from Lancaster to Key West is to fly which costs $95 - $410 and takes 9h 14m.
The fastest way to get from Lancaster to Key West is to train and fly which takes 8h 30m and costs $170 - $650.
No, there is no direct bus from Lancaster station to Key West. However, there are services departing from Queen St. Station and arriving at N Roosevelt & 3rd Street via Harrisburg Bus Station, Washington Union Station, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 35h 16m.
The distance between Lancaster and Key West is 1178 miles. The road distance is 1318.5 miles.
The best way to get from Lancaster to Key West without a car is to bus which takes 35h 16m and costs $220 - $350.
It takes approximately 9h 14m to get from Lancaster to Key West, including transfers.
Lancaster to Key West bus services, operated by Greyhound USA, depart from Harrisburg Bus Station.
The best way to get from Lancaster to Key West is to fly which takes 9h 14m and costs $95 - $410. Alternatively, you can bus, which costs $220 - $350 and takes 35h 16m.
Lancaster to Key West bus services, operated by Greyhound USA, arrive at Washington Union Station.
Yes, the driving distance between Lancaster to Key West is 1319 miles. It takes approximately 23h 16m to drive from Lancaster to Key West.
What companies run services between Lancaster, PA, USA and Key West, FL, USA?
Delta, American Airlines, and United Airlines fly from Harrisburg International Airport (MDT) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from Queen St. Station to N Roosevelt & 3rd Street via AMTRAK ETown, Elizabethtown Amtrak Station, Harrisburg, Harrisburg Bus Station, Washington Union Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 35h 16m.
- Website
- aa.com
Flights from Harrisburg International Airport to Key West International Airport via Charlotte
- Ave. Duration
- 5h 13m
- When
- Every day
- Estimated price
- $80–390
Flights from Harrisburg International Airport to Key West International Airport via Philadelphia International Airport
- Ave. Duration
- 5h 24m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $80–390
Flights from Harrisburg International Airport to Key West International Airport via Miami
- Ave. Duration
- 8h 3m
- When
- Saturday
- Estimated price
- $80–390
Flights from Philadelphia International Airport to Key West International Airport
- Ave. Duration
- 3h 17m
- When
- Every day
- Estimated price
- $110–550
Flights from Philadelphia International Airport to Key West International Airport via Miami
- Ave. Duration
- 5h 31m
- When
- Every day
- Estimated price
- $110–550
Flights from Ronald Reagan Washington National Airport to Key West International Airport
- Ave. Duration
- 3h 14m
- When
- Every day
- Estimated price
- $110–600
Flights from Ronald Reagan Washington National Airport to Key West International Airport via Miami
- Ave. Duration
- 4h 56m
- When
- Every day
- Estimated price
- $110–600
Flights from Baltimore-Washington International Airport to Key West International Airport via Miami
- Ave. Duration
- 4h 55m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $95–470
Flights from Baltimore-Washington International Airport to Key West International Airport via Charlotte
- Ave. Duration
- 5h 24m
- When
- Every day
- Estimated price
- $95–470
Flights from Newark Liberty International Airport to Key West International Airport via Miami
- Ave. Duration
- 5h 43m
- When
- Every day
- Estimated price
- $90–430
Flights from Washington Dulles International Airport to Key West International Airport via Charlotte
- Ave. Duration
- 5h 31m
- When
- Every day
- Estimated price
- $75–390
- Website
- delta.com
Flights from Harrisburg International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 7m
- When
- Every day
- Estimated price
- $85–400
Flights from Philadelphia International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 31m
- When
- Every day
- Estimated price
- $120–600
Flights from Ronald Reagan Washington National Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 7m
- When
- Every day
- Estimated price
- $130–650
Flights from Baltimore-Washington International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 8m
- When
- Every day
- Estimated price
- $100–500
Flights from Newark Liberty International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 46m
- When
- Every day
- Estimated price
- $100–460
Flights from Washington Dulles International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $85–410
- Website
- united.com
Flights from Harrisburg International Airport to Key West International Airport via Washington Dulles International Airport
- Ave. Duration
- 5h 52m
- When
- Monday, Friday, Saturday, and Sunday
- Estimated price
- $75–380
Flights from Newark Liberty International Airport to Key West International Airport
- Ave. Duration
- 3h 28m
- When
- Every day
- Estimated price
- $85–430
Flights from Washington Dulles International Airport to Key West International Airport
- Ave. Duration
- 3h 7m
- When
- Every day
- Estimated price
- $75–380
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Elizabethtown Amtrak Station to 30th Street Station
- Ave. Duration
- 1h 27m
- Frequency
- Every 2 hours
- Estimated price
- $45–75
- Website
- Amtrak
Train from 30th Street Station to Fort Lauderdale Amtrak Station
- Ave. Duration
- 25h 51m
- Frequency
- Once daily
- Estimated price
- $700–1,100
- Website
- Amtrak
Train from Elizabethtown Amtrak Station to 30th Street Station
- Ave. Duration
- 1h 27m
- Frequency
- Every 2 hours
- Estimated price
- $45–75
- Website
- Amtrak
Train from Elizabethtown Amtrak Station to 30th Street Station
- Ave. Duration
- 1h 27m
- Frequency
- Every 2 hours
- Estimated price
- $45–75
- Website
- Amtrak
Train from 30th Street Station to Washington Union Station
- Ave. Duration
- 1h 58m
- Frequency
- Hourly
- Estimated price
- $70–120
- Website
- Amtrak
Train from Elizabethtown Amtrak Station to 30th Street Station
- Ave. Duration
- 1h 27m
- Frequency
- Every 2 hours
- Estimated price
- $45–75
- Website
- Amtrak
Train from 30th Street Station to BWI Thurgood Marshall
- Ave. Duration
- 1h 25m
- Frequency
- Hourly
- Estimated price
- $55–90
- Website
- Amtrak
Train from Elizabethtown Amtrak Station to 30th Street Station
- Ave. Duration
- 1h 27m
- Frequency
- Every 2 hours
- Estimated price
- $45–75
- Website
- Amtrak
Train from 30th Street Station to Newark Liberty International Airport
- Ave. Duration
- 56 min
- Frequency
- Every 3 hours
- Estimated price
- $40–70
- Website
- Amtrak
Train from Elizabethtown Amtrak Station to 30th Street Station
- Ave. Duration
- 1h 27m
- Frequency
- Every 2 hours
- Estimated price
- $45–75
- Website
- Amtrak
Train from 30th Street Station to Washington Union Station
- Ave. Duration
- 1h 58m
- Frequency
- Hourly
- Estimated price
- $70–120
- Website
- Amtrak
- Phone
- +1 800-874-7245
- [email protected]
- Website
- Tri Rail
Train from Fort Lauderdale Station to Miami Airport Station
- Ave. Duration
- 50 min
- Frequency
- Hourly
- Estimated price
- $4–6
- Website
- Tri Rail
- Weekend | Holiday
- $5
- Weekday
- $4–6
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from 30th Street Station to Washington Union Station
- Ave. Duration
- 1h 49m
- Frequency
- Hourly
- Estimated price
- $30–650
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $30–470
- First Class
- $150–650
Train from 30th Street Station to BWI Thurgood Marshall
- Ave. Duration
- 1h 22m
- Frequency
- 5 times a day
- Estimated price
- $24–650
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $24–460
- First Class
- $140–650
Train from 30th Street Station to Washington Union Station
- Ave. Duration
- 1h 49m
- Frequency
- Hourly
- Estimated price
- $30–650
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $30–470
- First Class
- $150–650
Subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platform
- Ave. Duration
- 50 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–3
- Website
- Washington Metropolitan Area Transit Authority
- standard fare after 9:30 p.m
- $2–3
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Harrisburg Bus Station to Washington Union Station
- Ave. Duration
- 2h 40m
- Frequency
- 4 times a week
- Estimated price
- $20–30
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $22–35
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $22–35
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Washington Union Station to Miami Airport Station
- Ave. Duration
- 21h 20m
- Frequency
- 4 times a week
- Estimated price
- $170–260
- Schedules at
- Flixbus USA
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- Key West Transit
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- Key West Transit
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
Booking & Getting There
There are 965+ hotels available in Key West.
















