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How to get fromLancaster to Lafayetteby plane, train, bus (Greyhound, Amtrak), train (Amtrak), car, shuttle, subway, or bus (Flixbus, Amtrak)

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There are 10 ways to get from Lancaster to Lafayette by plane, train, bus (Greyhound, Amtrak), train (Amtrak), car, shuttle, subway, or bus (Flixbus, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Lancaster to Chicago O'Hare International Airport, train

    best
    1. Fly from Lancaster (LNS) to Chicago O'Hare International Airport (ORD)plane plane LNS - ORD
    2. Take the train from Chicago Union Station to Lafayette Amtrak Stationtrain train
    8h 59m
    $94–392

  2. Bus

    1. Take the bus from Harrisburg Bus Station to Indianapolis Union Stationbus bus Greyhound US0421
    2. Take the bus from Indianapolis Union Station to Lafayette Amtrak Stationbus bus
    18h 59m
    $99–216

  3. Train (Amtrak)

    1. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train Keystone Service / ...
    2. Take the train from 30th Street Station to Lafayette Amtrak Stationtrain train Cardinal
    28h 11m
    $306–655

  4. Drive 632.5 mi

    1. Drive from Lancaster to Lafayettecar car 632.5 mi
    11h
    $116–167

  5. Train to Philadelphia International Airport, fly to Indianapolis, shuttle

    1. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Indianapolis (IND)plane plane PHL - IND
    3. Take a shuttle bus from Indianapolis Airport to Holiday Inn City Centreshuttle bus
    8h 57m
    $153–893

  6. Train, train to Baltimore-Washington International Airport, fly to Indianapolis, shuttle

    1. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to BWI Thurgood Marshalltrain train
    3. Fly from Baltimore-Washington International Airport (BWI) to Indianapolis (IND)plane plane BWI - IND
    4. Take a shuttle bus from Indianapolis Airport to Holiday Inn City Centreshuttle bus
    9h 58m
    $464–1,840

  7. Fly Harrisburg International Airport to Chicago O'Hare International Airport, train

    1. Fly from Harrisburg International Airport (MDT) to Chicago O'Hare International Airport (ORD)plane plane MDT - ORD
    2. Take the train from Chicago Union Station to Lafayette Amtrak Stationtrain train
    11h 31m
    $98–408

  8. Train, train to Ronald Reagan Washington National Airport, fly to Indianapolis, shuttle

    1. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to Washington Union Stationtrain train
    3. Fly from Ronald Reagan Washington National Airport (DCA) to Indianapolis (IND)plane plane DCA - IND
    4. Take a shuttle bus from Indianapolis Airport to Holiday Inn City Centreshuttle bus
    10h 48m
    $1,024–2,347

  9. Train, subway to Washington Dulles International Airport, fly to Indianapolis, shuttle

    1. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to Washington Union Stationtrain train
    3. Take the subway from Farragut West, Blue/Orange/Silver Line Track 2 Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    4. Fly from Washington Dulles International Airport (IAD) to Indianapolis (IND)plane plane IAD - IND
    5. Take a shuttle bus from Indianapolis Airport to Holiday Inn City Centreshuttle bus
    11h 16m
    $534–1,846

  10. Bus via Chicago

    1. Take the bus from Harrisburg Bus Station to Chicago Bus Stationbus bus FlixBus N2640 / ...
    2. Take the bus from Chicago Union Station to Lafayette Amtrak Stationbus bus Chicago
    23h 28m
    $138–246

Lancaster to Lafayette by bus and train

Calendar14Weekly Services
Duration18h 59mAverage Duration
Ticket$99Cheapest Price
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Questions & Answers

Map of how to get from Lancaster to Lafayette.ExpandLaunch map view
  • Distance: 763.2 mi
  • Duration: 8h 59m

What companies run services between Lancaster, PA, USA and Lafayette, IN, USA?

You can take a bus from Queen St. Station to Lafayette Amtrak Station via AMTRAK ETown, Elizabethtown Amtrak Station, Harrisburg, Harrisburg Bus Station, and Indianapolis Union Station in around 18h 59m. Alternatively, you can take a bus from W. Walnut & N. Mary St. to Lafayette Amtrak Station via AMTRAK ETown, Elizabethtown Amtrak Station, and 30th Street Station in around 28h 11m.

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