There are 4 ways to get from Lancaster to Millsboro by train, bus, car, shuttle, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain
- Take the train from 30th Street Station to Wilmingtontrain
- Take the bus from Wilmington Tc to Rehoboth P-N-R @ Country Club Rdbus 305
8h 31m$39–616Drive 128.6 mi
cheapest- Drive from Lancaster to Millsborocar 128.6 mi
2h 53m$24–34Line 18 bus, train, shuttle, line 215 bus
- Take the bus from Queen St. Station to AMTRAK ETownbus 18
- Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain
- Take a shuttle bus from Philadelphia Airport to Lewes Transit Center
- Take the bus from Rehoboth P-N-R @ Country Club Rd to Monroe St At Brandywine Village Aptsbus 215
8h 51mBus
- Take the bus from Harrisburg Bus Station to Philadelphia Bus Stationbus
- Take the bus from Philadelphia Bus Station to Wilmington Bus Stationbus
- Take the bus from Wilmington Tc to Rehoboth P-N-R @ Country Club Rdbus 305
12h 4m$32–65
Lancaster to Millsboro by bus and train
Questions & Answers
The cheapest way to get from Lancaster to Millsboro is to drive which costs $23 - $35 and takes 2h 53m.
The fastest way to get from Lancaster to Millsboro is to drive which takes 2h 53m and costs $23 - $35.
No, there is no direct bus from Lancaster station to Millsboro. However, there are services departing from Queen St. Station and arriving at Monroe St At Brandywine Village Apts via Harrisburg Bus Station, Philadelphia Bus Station, Wilmington Tc and Rehoboth P-N-R @ Country Club Rd. The journey, including transfers, takes approximately 12h 4m.
The distance between Lancaster and Millsboro is 245 miles. The road distance is 129.4 miles.
The best way to get from Lancaster to Millsboro without a car is to train and bus which takes 8h 31m and costs $35 - $650.
It takes approximately 8h 31m to get from Lancaster to Millsboro, including transfers.
Lancaster to Millsboro bus services, operated by Greyhound USA, depart from Harrisburg Bus Station.
Lancaster to Millsboro bus services, operated by Greyhound USA, arrive at Philadelphia Bus Station.
Yes, the driving distance between Lancaster to Millsboro is 129 miles. It takes approximately 2h 53m to drive from Lancaster to Millsboro.
There are 1349+ hotels available in Millsboro.
What companies run services between Lancaster, PA, USA and Millsboro, DE, USA?
You can take a bus from Queen St. Station to Monroe St At Brandywine Village Apts via AMTRAK ETown, Elizabethtown Amtrak Station, Harrisburg, Harrisburg Bus Station, Philadelphia Bus Station, Wilmington Bus Station, Wilmington Tc, and Rehoboth P-N-R @ Country Club Rd in around 12h 4m.
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Elizabethtown Amtrak Station to 30th Street Station
- Ave. Duration
- 1h 27m
- Frequency
- Every 2 hours
- Estimated price
- $27–60
- Website
- Amtrak
Train from 30th Street Station to Wilmington
- Ave. Duration
- 21 min
- Frequency
- Hourly
- Estimated price
- $8–17
- Website
- Amtrak
Train from Elizabethtown Amtrak Station to 30th Street Station
- Ave. Duration
- 1h 27m
- Frequency
- Every 2 hours
- Estimated price
- $27–60
- Website
- Amtrak
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from 30th Street Station to Wilmington
- Ave. Duration
- 24 min
- Frequency
- Every 2 hours
- Estimated price
- $5–550
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $5–440
- First Class
- $100–550
- Phone
- +1 800-652-3278
- Website
- DART
Bus from Wilmington Tc to Rehoboth P-N-R @ Country Club Rd
- Ave. Duration
- 2h 2m
- Frequency
- Twice daily
- Estimated price
- $5–7
- Website
- DART
Bus from Rehoboth P-N-R @ Country Club Rd to Monroe St At Brandywine Village Apts
- Ave. Duration
- 49 min
- Frequency
- Hourly
- Estimated price
- $2–3
- Website
- DART
Bus from Wilmington Tc to Rehoboth P-N-R @ Country Club Rd
- Ave. Duration
- 2h 2m
- Frequency
- Twice daily
- Estimated price
- $5–7
- Website
- DART
- Phone
- +1 717-397-4246
- Website
- Red Rose Transit
Bus from Queen St. Station to AMTRAK ETown
- Ave. Duration
- 1h 2m
- Frequency
- 4 times a day
- Website
- Red Rose Transit
- Phone
- +1 302-470-6784
- [email protected]
- Website
- Lewes Bus
Shuttle from Philadelphia Airport to Lewes Transit Center
- Ave. Duration
- 2h
- Frequency
- Twice daily
- Estimated price
- $70
- Schedules at
- Lewes Bus
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Harrisburg Bus Station to Philadelphia Bus Station
- Ave. Duration
- 2h 35m
- Frequency
- Every 4 hours
- Estimated price
- $16–35
- Website
- Greyhound
Bus from Philadelphia Bus Station to Wilmington Bus Station
- Ave. Duration
- 45 min
- Frequency
- Every 3 hours
- Estimated price
- $4–9
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Harrisburg Bus Station to Philadelphia Bus Station
- Ave. Duration
- 2h 45m
- Frequency
- Once daily
- Estimated price
- $17–28
- Schedules at
- Flixbus USA
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