There are 6 ways to get from Lancaster to Roanoke, VA by train (Amtrak), bus (Greyhound), car, plane, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train via Washington (Amtrak)
best- Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain
- Take the train from 30th Street Station to Washington Union Stationtrain
- Take the train from Washington Union Station to Roanoketrain
12h 4m$146–880Drive 298.7 mi
cheapest- Drive from Lancaster to Roanoke, VAcar 298.7 mi
5h 40m$55–79Bus (Greyhound)
- Take the bus from Harrisburg Bus Station to Washington Union Stationbus Greyhound US0430
- Take the bus from Washington Union Station to Roanoke Bus Stopbus Greyhound US0600
14h 57m$74–138Fly from Harrisburg International Airport
- Fly from Harrisburg International Airport (MDT) to Roanoke Regional Airport-Woodrum Field (ROA)plane MDT - ROA
8h 1m$114–679Train (Amtrak)
- Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain Keystone Service / ...
- Take the train from 30th Street Station to Roanoketrain Northeast Regional
12h 24m$156–320Line 18 bus, train to Philadelphia International Airport, fly
- Take the bus from Queen St. Station to AMTRAK ETownbus
- Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain
- Fly from Philadelphia International Airport (PHL) to Roanoke Regional Airport-Woodrum Field (ROA)plane PHL - ROA
6h 44m
Harrisburg International Airport (MDT) to Roanoke Regional Airport-Woodrum Field (ROA) flights
Questions & Answers
The cheapest way to get from Lancaster to Roanoke, VA is to drive which costs $50 - $80 and takes 5h 40m.
The fastest way to get from Lancaster to Roanoke, VA is to drive which takes 5h 40m and costs $50 - $80.
No, there is no direct bus from Lancaster station to Roanoke, VA. However, there are services departing from Queen St. Station and arriving at Airport via Harrisburg Bus Station, Washington Union Station and 3rd St Station Slip D. The journey, including transfers, takes approximately 14h 57m.
No, there is no direct train from Lancaster station to Roanoke, VA. However, there are services departing from Elizabethtown Amtrak Station and arriving at Roanoke via 30th Street Station and Washington Union Station. The journey, including transfers, takes approximately 12h 4m.
The distance between Lancaster and Roanoke, VA is 475 miles. The road distance is 300.5 miles.
The best way to get from Lancaster to Roanoke, VA without a car is to train via Washington which takes 12h 4m and costs $140 - $900.
It takes approximately 12h 4m to get from Lancaster to Roanoke, VA, including transfers.
Lancaster to Roanoke, VA bus services, operated by Greyhound USA, depart from Harrisburg Bus Station.
Lancaster to Roanoke, VA train services, operated by Amtrak, depart from Elizabethtown Amtrak Station.
The best way to get from Lancaster to Roanoke, VA is to train via Washington which takes 12h 4m and costs $140 - $900. Alternatively, you can bus, which costs $70 - $140 and takes 14h 57m, you could also fly, which costs $110 - $700 and takes 8h 1m.
What companies run services between Lancaster, PA, USA and Roanoke, VA, USA?
You can take a bus from W. Walnut & N. Mary St. to Roanoke, VA via AMTRAK ETown, Elizabethtown Amtrak Station, 30th Street Station, Washington Union Station, and Roanoke in around 12h 4m. Alternatively, you can take a bus from Queen St. Station to Roanoke, VA via AMTRAK ETown, Elizabethtown Amtrak Station, Harrisburg, Harrisburg Bus Station, Washington Union Station, 3rd St Station Slip D, and Airport in around 14h 57m.
- Website
- aa.com
Flights from Harrisburg International Airport to Roanoke Regional Airport-Woodrum Field via Charlotte
- Ave. Duration
- 4h 32m
- When
- Every day
- Estimated price
- $140–750
Flights from Harrisburg International Airport to Roanoke Regional Airport-Woodrum Field via Philadelphia International Airport
- Ave. Duration
- 5h 36m
- When
- Every day
- Estimated price
- $110–700
Flights from Philadelphia International Airport to Roanoke Regional Airport-Woodrum Field
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- $65–430
- Website
- united.com
Flights from Harrisburg International Airport to Roanoke Regional Airport-Woodrum Field via Washington Dulles
- Ave. Duration
- 3h 45m
- When
- Every day
- Estimated price
- $95–650
Flights from Harrisburg International Airport to Roanoke Regional Airport-Woodrum Field via Chicago O'Hare
- Ave. Duration
- 6h 38m
- When
- Every day
- Estimated price
- $210–1,000
Flights from Philadelphia International Airport to Roanoke Regional Airport-Woodrum Field via Washington Dulles
- Ave. Duration
- 3h 48m
- When
- Monday to Saturday
- Estimated price
- $65–430
- Website
- delta.com
Flights from Harrisburg International Airport to Roanoke Regional Airport-Woodrum Field via Atlanta
- Ave. Duration
- 6h 14m
- When
- Every day
- Estimated price
- $190–950
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Elizabethtown Amtrak Station to 30th Street Station
- Ave. Duration
- 1h 27m
- Frequency
- Every 2 hours
- Estimated price
- $27–60
- Website
- Amtrak
Train from 30th Street Station to Washington Union Station
- Ave. Duration
- 1h 58m
- Frequency
- Hourly
- Estimated price
- $40–90
- Website
- Amtrak
Train from Washington Union Station to Roanoke
- Ave. Duration
- 5h 10m
- Frequency
- Twice daily
- Estimated price
- $70–150
- Website
- Amtrak
Train from Elizabethtown Amtrak Station to 30th Street Station
- Ave. Duration
- 1h 27m
- Frequency
- Every 2 hours
- Estimated price
- $27–60
- Website
- Amtrak
Train from 30th Street Station to Roanoke
- Ave. Duration
- 7h 43m
- Frequency
- Twice daily
- Estimated price
- $110–240
- Website
- Amtrak
Train from Elizabethtown Amtrak Station to 30th Street Station
- Ave. Duration
- 1h 27m
- Frequency
- Every 2 hours
- Estimated price
- $27–60
- Website
- Amtrak
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from 30th Street Station to Washington Union Station
- Ave. Duration
- 1h 49m
- Frequency
- Hourly
- Estimated price
- $30–650
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $30–470
- First Class
- $150–650
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Harrisburg Bus Station to Washington Union Station
- Ave. Duration
- 3h 15m
- Frequency
- Twice daily
- Estimated price
- $17–35
- Website
- Greyhound
Bus from Washington Union Station to Roanoke Bus Stop
- Ave. Duration
- 6h 9m
- Frequency
- Twice daily
- Estimated price
- $35–70
- Website
- Greyhound
- Phone
- +1 717-397-4246
- Website
- Red Rose Transit
Bus from Queen St. Station to AMTRAK ETown
- Ave. Duration
- 1h 2m
- Frequency
- 4 times a day
- Website
- Red Rose Transit
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More Questions & Answers
Lancaster to Roanoke, VA bus services, operated by Greyhound USA, arrive at Washington Union Station.
Lancaster to Roanoke, VA train services, operated by Amtrak, arrive at 30th Street Station.
Yes, the driving distance between Lancaster to Roanoke, VA is 300 miles. It takes approximately 5h 40m to drive from Lancaster to Roanoke, VA.
There are 81+ hotels available in Roanoke, VA.







