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How to get fromLancaster to South Carolinaby bus, plane, taxi, train (Amtrak), car, or train

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There are 7 ways to get from Lancaster to South Carolina by bus, plane, taxi, train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 18 bus to Harrisburg International Airport, fly to Charlotte Douglas International Airport, taxi

    best
    1. Take the bus from Queen St. Station to AMTRAK ETownbus bus
    2. Fly from Harrisburg International Airport (MDT) to Charlotte Douglas International Airport (CLT)plane plane MDT - CLT
    3. Take the taxi from Charlotte-Airport-CLT to Rock Hilltaxi taxi
    6h 36m

  2. Drive 604.8 mi

    cheapest
    1. Drive from Lancaster to Charlestoncar car 604.8 mi
    11h 50m
    $111–160

  3. Train (Amtrak)

    1. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train Keystone Service / ...
    2. Take the train from 30th Street Station to Charleston Amtrak Stationtrain train Silver Meteor / ...
    17h 12m
    $246–515

  4. Line 18 bus, train to Philadelphia International Airport, fly to Greenville–Spartanburg International Airport

    1. Take the bus from Queen St. Station to AMTRAK ETownbus bus
    2. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train
    3. Fly from Philadelphia International Airport (PHL) to Greenville–Spartanburg International Airport (GSP)plane plane PHL - GSP
    7h 23m

  5. Train to Philadelphia International Airport, fly to Charleston International Airport

    1. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Charleston International Airport (CHS)plane plane PHL - CHS
    8h 6m
    $681–960

  6. Train, train to Baltimore-Washington International Airport, fly to Greenville–Spartanburg International Airport

    1. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to BWI Thurgood Marshalltrain train
    3. Fly from Baltimore-Washington International Airport (BWI) to Greenville–Spartanburg International Airport (GSP)plane plane BWI - GSP
    8h 15m
    $180–1,350

  7. Train, train to Baltimore-Washington International Airport, fly to Charlotte Douglas International Airport, taxi

    1. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to BWI Thurgood Marshalltrain train
    3. Fly from Baltimore-Washington International Airport (BWI) to Charlotte Douglas International Airport (CLT)plane plane BWI - CLT
    4. Take the taxi from Charlotte-Airport-CLT to Rock Hilltaxi taxi
    8h 30m
    $225–1,125

Harrisburg International Airport (MDT) to Charlotte Douglas International Airport (CLT) flights

Calendar81Weekly Planes
Duration2h 41mAverage Duration
Ticket$81Cheapest Price
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Questions & Answers

Map of how to get from Lancaster to South Carolina.ExpandLaunch map view
  • Distance: 490.7 mi
  • Duration: 6h 36m

What companies run services between Lancaster, PA, USA and South Carolina, USA?

You can take a bus from W. Walnut & N. Mary St. to Charleston via AMTRAK ETown, Elizabethtown Amtrak Station, 30th Street Station, and Charleston Amtrak Station in around 17h 12m.

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