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How to get fromLancaster to Winston-Salemby train, plane, bus, bus (Greyhound), car, or subway

Find Transport to Winston-Salem

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There are 7 ways to get from Lancaster to Winston-Salem by train, plane, bus, bus (Greyhound), car, or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Philadelphia International Airport, fly to Piedmont Triad International Airport

    best
    1. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Piedmont Triad International Airport (GSO)plane plane PHL - GSO
    7h 54m
    $169–832

  2. Drive 408.7 mi

    cheapest
    1. Drive from Lancaster to Winston-Salemcar car 408.7 mi
    8h 7m
    $75–108

  3. Train, bus

    1. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to Greensborotrain train
    3. Take the bus from Greensboro Bus Stop to Winston Salem(Trans Center)bus bus
    14h 42m
    $161–344

  4. Bus (Greyhound)

    1. Take the bus from Harrisburg Bus Station to Washington Union Stationbus bus Greyhound US0430
    2. Take the bus from Washington Union Station to Winston Salem(Trans Center)bus bus Greyhound US0670
    16h 9m
    $77–156

  5. Line 18 bus, train to Harrisburg International Airport, fly to Charlotte Douglas International Airport, bus

    1. Take the bus from Queen St. Station to AMTRAK ETownbus bus
    2. Take the train from Elizabethtown Amtrak Station to Harrisburgtrain train
    3. Fly from Harrisburg International Airport (MDT) to Charlotte Douglas International Airport (CLT)plane plane MDT - CLT
    4. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    9h 15m

  6. Train, train to Ronald Reagan Washington National Airport, fly to Piedmont Triad International Airport

    1. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to Washington Union Stationtrain train
    3. Fly from Ronald Reagan Washington National Airport (DCA) to Piedmont Triad International Airport (GSO)plane plane DCA - GSO
    9h 39m
    $200–1,536

  7. Train, subway to Washington Dulles International Airport, fly to Piedmont Triad International Airport

    1. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to Washington Union Stationtrain train
    3. Take the subway from Farragut West, Blue/Orange/Silver Line Track 2 Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    4. Fly from Washington Dulles International Airport (IAD) to Piedmont Triad International Airport (GSO)plane plane IAD - GSO
    10h 11m
    $150–1,215

Lancaster to Winston-Salem by bus and train

Calendar14Weekly Services
Duration14h 42mAverage Duration
Ticket$161Cheapest Price
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Questions & Answers

Map of how to get from Lancaster to Winston-Salem.ExpandLaunch map view
  • Distance: 503.6 mi
  • Duration: 7h 54m

What companies run services between Lancaster, PA, USA and Winston-Salem, NC, USA?

You can take a bus from Queen St. Station to Winston Salem(Trans Center) via AMTRAK ETown, Elizabethtown Amtrak Station, Harrisburg, Harrisburg Bus Station, and Washington Union Station in around 16h 9m.

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