Rome2Rio

How to get fromLancaster to Knoxvilleby taxi, plane, bus, shuttle, or car

Find Transport to Knoxville

See all options

There are 4 ways to get from Lancaster to Knoxville by taxi, plane, bus, shuttle, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi, fly

    best
    1. Take the taxi from Lancaster to Charlotte-Airport-CLTtaxi taxi
    2. Fly from Charlotte Douglas International Airport (CLT) to Mcghee Tyson Airport (TYS)plane plane CLT - TYS
    2h 31m
    $264–866
  2. Drive 248.5 mi

    cheapest
    1. Drive from Lancaster to Knoxvillecar car 248.5 mi
    4h 56m
    $46–66
  3. Taxi, bus, shuttle, drive

    1. Take the taxi from Lancaster to I-485 Stationtaxi taxi
    2. Take the bus from Charlotte Airport to ASU Peacock Hall Boonebus bus
    3. Take a shuttle bus from Boone to Black Bear Resortshuttle bus
    4. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle bus
    5. Drive from Hot Springs to Knoxvillecar car
    10h 10m
    $452–501
  4. Taxi, bus, shuttle, drive via Chilhowee at Holston

    1. Take the taxi from Lancaster to Park Rd & Carolina Place Pkwytaxi taxi
    2. Take the bus from Charlotte Airport to ASU Peacock Hall Boonebus bus
    3. Take the taxi from ASU Peacock Hall Boone to Black Bear Resorttaxi taxi
    4. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle bus
    5. Drive from Hot Springs to Chilhowee at Holstoncar car
    10h 59m
    $474–553

Charlotte Douglas International Airport (CLT) to Mcghee Tyson Airport (TYS) flights

Calendar64Weekly Planes
Duration1h 38mAverage Duration
Ticket$87Cheapest Price
See schedules

Questions & Answers

What companies run services between Lancaster, SC, USA and Knoxville, TN, USA?

There is no direct connection from Lancaster to Knoxville. However, you can take the taxi to Charlotte-Airport-CLT airport, fly to Mcghee Tyson Airport (TYS), then take the taxi to Knoxville. Alternatively, you can take the taxi to I-485 Station, take the line 501 vehicle to Tyvola Station, walk to Tyvola Station, take the line 60 bus to Charlotte Douglas Airport, walk to Charlotte Airport, take the bus to ASU Peacock Hall Boone, walk to Boone, take the shuttle to Black Bear Resort, take the shuttle to Hot Springs, then drive to Knoxville.

Airlines
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides