There are 10 ways to get from Lansdale to Buffalo by train, plane, train (Amtrak), bus (Greyhound), car, bus, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Philadelphia International Airport, fly to Buffalo Niagara International Airport
best- Take the train from Lansdale to Suburban Stationtrain
- Fly from Philadelphia International Airport (PHL) to Buffalo Niagara International Airport (BUF)plane PHL - BUF
5h 25m$120–836Drive 322.1 mi
cheapest- Drive from Lansdale to Buffalocar 322.1 mi
6h 40m$57–83Train
- Take the train from Lansdale to Suburban Stationtrain Lan
- Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain
12h 21m$265–988Bus via Scranton (Greyhound)
- Take the bus from Doylestown SEPTA Station to Scranton Bus Stationbus Greyhound US0340s
- Take the bus from Scranton Bus Station to Buffalobus Greyhound US0205 / ...
12h 22m$75–114Train to Philadelphia International Airport, fly to Rochester, bus
- Take the train from Lansdale to Suburban Stationtrain
- Fly from Philadelphia International Airport (PHL) to Rochester (ROC)plane PHL - ROC
- Take the bus from Rochester Bus Stop to Buffalobus
6h 49m$174–1,051Train, train to Baltimore-Washington International Airport, fly to Buffalo Niagara International Airport
- Take the train from Lansdale to Jefferson Stationtrain
- Take the train from 30th Street Station to BWI Thurgood Marshalltrain
- Fly from Baltimore-Washington International Airport (BWI) to Buffalo Niagara International Airport (BUF)plane BWI - BUF
6h 32m$124–1,286Train, train to John F. Kennedy International Airport, fly to Buffalo Niagara International Airport
- Take the train from Lansdale to Jefferson Stationtrain
- Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain
- Fly from John F. Kennedy International Airport (JFK) to Buffalo Niagara International Airport (BUF)plane JFK - BUF
6h 58m$109–1,095Train, train to Newark Liberty International Airport, fly to Buffalo Niagara International Airport
- Take the train from Lansdale to Jefferson Stationtrain
- Take the train from 30th Street Station to Newark Liberty International Airporttrain
- Fly from Newark Liberty International Airport (EWR) to Buffalo Niagara International Airport (BUF)plane EWR - BUF
6h 59m$130–656Train to Laguardia Airport, fly to Buffalo Niagara International Airport
- Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain
- Fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF)plane LGA - BUF
7h 43m$138–1,353Bus
- Take the bus from Philadelphia Bus Station to Newark Penn Stationbus Greyhound US0421 / ...
- Take the bus from Newark Penn Station to Buffalobus FlixBus 2686 / ...
13h 4m$82–140
Lansdale to Buffalo by train
Comparing Your Travel Options
The cheapest way to get from Lansdale to Buffalo is to drive which costs $55 - $85 and takes 6h 40m.
The fastest way to get from Lansdale to Buffalo is to train and fly which takes 5h 25m and costs $120 - $850.
No, there is no direct bus from Lansdale station to Buffalo. However, there are services departing from Doylestown SEPTA Station and arriving at Buffalo via Scranton Bus Station. The journey, including transfers, takes approximately 12h 22m.
No, there is no direct train from Lansdale to Buffalo. However, there are services departing from Lansdale and arriving at Buffalo via Suburban Station, 30th Street Station and Ny Moynihan Train Hall At Penn Station. The journey, including transfers, takes approximately 12h 21m.
The distance between Lansdale and Buffalo is 324 miles. The road distance is 324 miles.
The best way to get from Lansdale to Buffalo without a car is to train which takes 12h 21m and costs $260 - $1,000.
It takes approximately 5h 25m to get from Lansdale to Buffalo, including transfers.
Lansdale to Buffalo bus services, operated by Greyhound USA, depart from Doylestown SEPTA Station.
Lansdale to Buffalo train services, operated by SEPTA, depart from Lansdale station.
The best way to get from Lansdale to Buffalo is to train which takes 12h 21m and costs $260 - $1,000. Alternatively, you can bus via Scranton, which costs $75 - $120 and takes 12h 22m.
What companies run services between Lansdale, PA, USA and Buffalo, NY, USA?
You can take a train from Lansdale to Buffalo via Suburban Station, 30th Street Station, and Ny Moynihan Train Hall At Penn Station in around 12h 21m. Alternatively, you can take a train from Lansdale to Buffalo via Doylestown, Doylestown SEPTA Station, and Scranton Bus Station in around 12h 22m.
- Website
- delta.com
Flights from John F. Kennedy International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- $65–440
Flights from Laguardia Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $100–700
- Website
- united.com
Flights from Philadelphia International Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 3h 43m
- When
- Every day
- Estimated price
- $130–850
Flights from Philadelphia International Airport to Rochester via Washington Dulles
- Ave. Duration
- 3h 50m
- When
- Tuesday, Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $170–1,100
Flights from Newark Liberty International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $80–550
Flights from Newark Liberty International Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 3h 50m
- When
- Every day
- Estimated price
- $100–600
- Website
- aa.com
Flights from Philadelphia International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $110–800
Flights from Philadelphia International Airport to Rochester
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $140–1,000
Flights from Laguardia Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $100–700
- Website
- southwest.com
Flights from Baltimore-Washington International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 18m
- When
- Every day
- Estimated price
- $90–600
- Website
- jetblue.com
Flights from John F. Kennedy International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $65–440
- Phone
- +1 215-580-7800
- Website
- SEPTA
Train from Lansdale to Suburban Station
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- $3–5
- Website
- SEPTA
- Schedules at
- SEPTA: World Cup 2026
Train from Lansdale to Suburban Station
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- $3–5
- Website
- SEPTA
- Schedules at
- SEPTA: World Cup 2026
Train from Lansdale to Suburban Station
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- $3–5
- Website
- SEPTA
- Schedules at
- SEPTA: World Cup 2026
Train from Lansdale to Jefferson Station
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- $3–5
- Website
- SEPTA
- Schedules at
- SEPTA: World Cup 2026
Train from Lansdale to Jefferson Station
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- $3–5
- Website
- SEPTA
- Schedules at
- SEPTA: World Cup 2026
Train from Lansdale to Jefferson Station
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- $3–5
- Website
- SEPTA
- Schedules at
- SEPTA: World Cup 2026
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from 30th Street Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 1h 24m
- Frequency
- Every 30 minutes
- Estimated price
- $50–80
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Buffalo
- Ave. Duration
- 8h 35m
- Frequency
- 3 times a day
- Estimated price
- $240–380
- Website
- Amtrak
Train from 30th Street Station to BWI Thurgood Marshall
- Ave. Duration
- 1h 25m
- Frequency
- Hourly
- Estimated price
- $55–90
- Website
- Amtrak
Train from 30th Street Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 1h 24m
- Frequency
- Every 30 minutes
- Estimated price
- $50–80
- Website
- Amtrak
Train from 30th Street Station to Newark Liberty International Airport
- Ave. Duration
- 56 min
- Frequency
- Every 3 hours
- Estimated price
- $40–70
- Website
- Amtrak
Train from 30th Street Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 1h 24m
- Frequency
- Every 30 minutes
- Estimated price
- $50–80
- Website
- Amtrak
Rome2Rio's guide to Amtrak Acela
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from 30th Street Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- $20–600
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $20–460
- First Class
- $130–600
Train from 30th Street Station to BWI Thurgood Marshall
- Ave. Duration
- 1h 22m
- Frequency
- 5 times a day
- Estimated price
- $24–650
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $24–460
- First Class
- $140–650
Train from 30th Street Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- $20–600
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $20–460
- First Class
- $130–600
Train from 30th Street Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- $20–600
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $20–460
- First Class
- $130–600
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Doylestown SEPTA Station to Scranton Bus Station
- Ave. Duration
- 4h 15m
- Frequency
- Once daily
- Estimated price
- $22–35
- Website
- Greyhound
Bus from Scranton Bus Station to Buffalo
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- $50–75
- Website
- Greyhound
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 20m
- Frequency
- 5 times a day
- Estimated price
- $13–21
- Website
- Greyhound
Bus from Philadelphia Bus Station to Newark Penn Station
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $14–22
- Website
- Greyhound
Bus from Newark Penn Station to Buffalo
- Ave. Duration
- 8h 35m
- Frequency
- Once daily
- Estimated price
- $70–110
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $11–18
- Schedules at
- Flixbus USA
Bus from Philadelphia Bus Station to Newark Penn Station
- Ave. Duration
- 1h 50m
- Frequency
- Every 3 hours
- Estimated price
- $12–19
- Schedules at
- Flixbus USA
Bus from Newark Penn Station to Buffalo
- Ave. Duration
- 7h 55m
- Frequency
- 5 times a day
- Estimated price
- $65–95
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
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Booking & Getting There
Lansdale to Buffalo bus services, operated by Greyhound USA, arrive at Scranton Bus Station.
Lansdale to Buffalo train services, operated by SEPTA, arrive at Suburban Station.
Yes, the driving distance between Lansdale to Buffalo is 324 miles. It takes approximately 6h 40m to drive from Lansdale to Buffalo.
There are 256+ hotels available in Buffalo.













