There are 8 ways to get from Lansdale to Greenville by train, plane, bus, bus (Greyhound, Flixbus), car, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Philadelphia International Airport, fly to Greenville–Spartanburg International Airport
best- Take the train from Lansdale to Suburban Stationtrain
- Fly from Philadelphia International Airport (PHL) to Greenville–Spartanburg International Airport (GSP)plane PHL - GSP
4h 57m$161–751Train to Philadelphia International Airport, fly to Columbia, drive
cheapest- Take the train from Lansdale to Suburban Stationtrain
- Fly from Philadelphia International Airport (PHL) to Columbia (CAE)plane PHL - CAE
- Drive from Columbia-Airport-CAE to Greenvillecar
6h 34m$104–514Train, bus
- Take the train from Lansdale to Suburban Stationtrain Lan
- Take the train from 30th Street Station to Charlotte Amtrak Stationtrain
- Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus
17h 2m$212–508Bus
- Take the bus from Philadelphia Bus Station to Charlotte Bus Stationbus Greyhound US0670
- Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus Charlotte
21h 46m$148–341Drive 630.1 mi
- Drive from Lansdale to Greenvillecar 630.1 mi
11h 42m$115–167Train to Philadelphia International Airport, fly to Asheville Regional Airport, taxi
- Take the train from Lansdale to Suburban Stationtrain
- Fly from Philadelphia International Airport (PHL) to Asheville Regional Airport (AVL)plane PHL - AVL
- Take the taxi from Asheville-Airport-AVL to Greenvilletaxi
5h 45m$226–646Train, train to Baltimore-Washington International Airport, fly to Greenville–Spartanburg International Airport
- Take the train from Lansdale to Jefferson Stationtrain
- Take the train from 30th Street Station to BWI Thurgood Marshalltrain
- Fly from Baltimore-Washington International Airport (BWI) to Greenville–Spartanburg International Airport (GSP)plane BWI - GSP
5h 48m$160–1,301Train to Newark Liberty International Airport, fly to Greenville–Spartanburg International Airport
- Take the train from 30th Street Station to Newark Liberty International Airporttrain
- Fly from Newark Liberty International Airport (EWR) to Greenville–Spartanburg International Airport (GSP)plane EWR - GSP
6h 35m$485–1,206
Philadelphia International Airport (PHL) to Greenville–Spartanburg International Airport (GSP) flights
Questions & Answers
The cheapest way to get from Lansdale to Greenville is to drive which costs $110 - $170 and takes 11h 42m.
The fastest way to get from Lansdale to Greenville is to train and fly which takes 4h 57m and costs $160 - $750.
No, there is no direct bus from Lansdale to Greenville. However, there are services departing from Main St & Highland Av - MBNS and arriving at Taqueria Guadalajara - Greenville via Chestnut Hill Loop, Philadelphia Bus Station, Trade St & Graham St, Transit Center- Bay O and Charlotte. The journey, including transfers, takes approximately 21h 46m.
The distance between Lansdale and Greenville is 564 miles. The road distance is 633.7 miles.
The best way to get from Lansdale to Greenville without a car is to train and bus which takes 17h 2m and costs $210 - $550.
It takes approximately 4h 57m to get from Lansdale to Greenville, including transfers.
Lansdale to Greenville bus services, operated by Greyhound USA, depart from Philadelphia Bus Station.
Lansdale to Greenville bus services, operated by Greyhound USA, arrive at Charlotte Bus Station.
Yes, the driving distance between Lansdale to Greenville is 634 miles. It takes approximately 11h 42m to drive from Lansdale to Greenville.
There are 268+ hotels available in Greenville.
What companies run services between Lansdale, PA, USA and Greenville, SC, USA?
You can take a bus from Main St & Highland Av - MBNS to Greenville via Chestnut Hill Loop, 12th St & Market St, Philadelphia Bus Station, Charlotte Bus Station, Trade St & Graham St, Transit Center- Bay A, Transit Center- Bay O, Tryon St & Dorton St, Charlotte, and Taqueria Guadalajara - Greenville in around 21h 46m.
- Website
- aa.com
Flights from Philadelphia International Airport to Greenville–Spartanburg International Airport
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- $120–700
Flights from Philadelphia International Airport to Greenville–Spartanburg International Airport via Charlotte
- Ave. Duration
- 3h 59m
- When
- Every day
- Estimated price
- $120–700
Flights from Philadelphia International Airport to Asheville Regional Airport
- Ave. Duration
- 2h 5m
- When
- Every day
- Estimated price
- $80–470
Flights from Philadelphia International Airport to Asheville Regional Airport via Charlotte
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- $85–480
Flights from Philadelphia International Airport to Asheville Regional Airport via Reagan Washington
- Ave. Duration
- 3h 54m
- When
- Monday to Friday
- Estimated price
- $80–470
Flights from Baltimore-Washington International Airport to Greenville–Spartanburg International Airport via Charlotte
- Ave. Duration
- 3h 41m
- When
- Every day
- Estimated price
- $95–600
Flights from Philadelphia International Airport to Columbia
- Ave. Duration
- 2h 3m
- When
- Every day
- Estimated price
- $80–480
Flights from Philadelphia International Airport to Columbia via Charlotte
- Ave. Duration
- 4h 42m
- When
- Every day
- Estimated price
- $85–480
Flights from Newark Liberty International Airport to Greenville–Spartanburg International Airport via Charlotte
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- $100–550
- Website
- delta.com
Flights from Philadelphia International Airport to Greenville–Spartanburg International Airport via Atlanta
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- $160–850
Flights from Philadelphia International Airport to Asheville Regional Airport via Atlanta
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- $110–600
Flights from Baltimore-Washington International Airport to Greenville–Spartanburg International Airport via Atlanta
- Ave. Duration
- 3h 41m
- When
- Every day
- Estimated price
- $130–700
Flights from Philadelphia International Airport to Columbia via Atlanta
- Ave. Duration
- 4h 38m
- When
- Every day
- Estimated price
- $110–600
Flights from Newark Liberty International Airport to Greenville–Spartanburg International Airport via Atlanta
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- $130–650
- Website
- united.com
Flights from Philadelphia International Airport to Greenville–Spartanburg International Airport via Washington Dulles
- Ave. Duration
- 3h 54m
- When
- Every day
- Estimated price
- $120–700
Flights from Philadelphia International Airport to Columbia via Washington Dulles
- Ave. Duration
- 3h 56m
- When
- Every day
- Estimated price
- $85–480
Flights from Newark Liberty International Airport to Greenville–Spartanburg International Airport
- Ave. Duration
- 2h 12m
- When
- Every day
- Estimated price
- $100–550
Flights from Newark Liberty International Airport to Greenville–Spartanburg International Airport via Washington Dulles
- Ave. Duration
- 3h 57m
- When
- Every day
- Estimated price
- $100–550
- Website
- southwest.com
Flights from Baltimore-Washington International Airport to Greenville–Spartanburg International Airport
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $95–600
- Phone
- +1 215-580-7800
- Website
- SEPTA
Train from Lansdale to Suburban Station
- Ave. Duration
- 57 min
- Frequency
- Hourly
- Estimated price
- $3
- Website
- SEPTA
- Schedules at
- SEPTA: World Cup 2026
Train from Lansdale to Suburban Station
- Ave. Duration
- 57 min
- Frequency
- Hourly
- Estimated price
- $3
- Website
- SEPTA
- Schedules at
- SEPTA: World Cup 2026
Train from Lansdale to Suburban Station
- Ave. Duration
- 57 min
- Frequency
- Hourly
- Estimated price
- $3
- Website
- SEPTA
- Schedules at
- SEPTA: World Cup 2026
Train from Lansdale to Jefferson Station
- Ave. Duration
- 52 min
- Frequency
- Hourly
- Estimated price
- $3
- Website
- SEPTA
- Schedules at
- SEPTA: World Cup 2026
Train from Lansdale to Suburban Station
- Ave. Duration
- 57 min
- Frequency
- Hourly
- Estimated price
- $3
- Website
- SEPTA
- Schedules at
- SEPTA: World Cup 2026
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from 30th Street Station to Charlotte Amtrak Station
- Ave. Duration
- 10h 52m
- Frequency
- Twice daily
- Estimated price
- $150–340
- Website
- Amtrak
Train from 30th Street Station to BWI Thurgood Marshall
- Ave. Duration
- 1h 25m
- Frequency
- Hourly
- Estimated price
- $30–70
- Website
- Amtrak
Train from 30th Street Station to Newark Liberty International Airport
- Ave. Duration
- 56 min
- Frequency
- Every 3 hours
- Estimated price
- $24–55
- Website
- Amtrak
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from 30th Street Station to BWI Thurgood Marshall
- Ave. Duration
- 1h 22m
- Frequency
- 5 times a day
- Estimated price
- $24–650
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $24–460
- First Class
- $140–650
- Phone
- +1 888 358 6762
- [email protected]
- Website
- Tornado Bus Company
Bus from Charlotte to Taqueria Guadalajara - Greenville
- Ave. Duration
- 2h 27m
- Frequency
- Once daily
- Estimated price
- $40–140
- Schedules at
- Tornado Bus Company
- Adults 11-59
- $40–140
Bus from Charlotte to Taqueria Guadalajara - Greenville
- Ave. Duration
- 2h 27m
- Frequency
- Once daily
- Estimated price
- $40–140
- Schedules at
- Tornado Bus Company
- Adults 11-59
- $40–140
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Philadelphia Bus Station to Charlotte Bus Station
- Ave. Duration
- 14h 30m
- Frequency
- Once daily
- Estimated price
- $85–170
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Philadelphia Bus Station to Charlotte Bus Station
- Ave. Duration
- 14h 15m
- Frequency
- 4 times a week
- Estimated price
- $85–150
- Schedules at
- Flixbus USA
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