There are 8 ways to get from Lansdale to St. Louis by train, plane, bus (Greyhound), train (Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Philadelphia International Airport, fly
best- Take the train from Lansdale to Suburban Stationtrain
- Fly from Philadelphia International Airport (PHL) to Lambert–St. Louis International Airport (STL)plane PHL - STL
5h 47m$128–761Bus (Greyhound)
- Take the bus from Philadelphia Bus Station to St Louis Bus Stationbus Greyhound US0421
22h 45m$143–234Train (Amtrak)
- Take the train from 30th Street Station to Washington Union Stationtrain
- Take the train from Washington Union Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to St. Louistrain
27h 53m$295–1,258Drive 872.5 mi
- Drive from Lansdale to St. Louiscar 872.5 mi
15h 11m$160–230Train to Baltimore-Washington International Airport, fly
- Take the train from 30th Street Station to BWI Thurgood Marshalltrain
- Fly from Baltimore-Washington International Airport (BWI) to Lambert–St. Louis International Airport (STL)plane BWI - STL
7h$142–1,311Train to Ronald Reagan Washington National Airport, fly
- Take the train from 30th Street Station to Washington Union Stationtrain
- Fly from Ronald Reagan Washington National Airport (DCA) to Lambert–St. Louis International Airport (STL)plane DCA - STL
7h 43m$172–1,098Train to Newark Liberty International Airport, fly
- Take the train from 30th Street Station to Newark Liberty International Airporttrain
- Fly from Newark Liberty International Airport (EWR) to Lambert–St. Louis International Airport (STL)plane EWR - STL
7h 33m$318–956Train to John F. Kennedy International Airport, fly
- Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain
- Fly from John F. Kennedy International Airport (JFK) to Lambert–St. Louis International Airport (STL)plane JFK - STL
7h 58m$152–1,230
Lansdale to St. Louis by train and bus (Greyhound)
Comparing Your Travel Options
The cheapest way to get from Lansdale to St. Louis is to bus which costs $140 - $240 and takes 22h 45m.
The fastest way to get from Lansdale to St. Louis is to train and fly which takes 5h 47m and costs $120 - $800.
No, there is no direct bus from Lansdale station to St. Louis station. However, there are services departing from Philadelphia Bus Station and arriving at St Louis Bus Station via . The journey, including transfers, takes approximately 22h 45m.
No, there is no direct train from Lansdale to St. Louis. However, there are services departing from Lansdale and arriving at St. Louis via 11th St, 30th Street Station, Washington Union Station and Chicago Union Station. The journey, including transfers, takes approximately 27h 53m.
The distance between Lansdale and St. Louis is 864 miles. The road distance is 877.6 miles.
The best way to get from Lansdale to St. Louis without a car is to bus which takes 22h 45m and costs $140 - $240.
It takes approximately 5h 47m to get from Lansdale to St. Louis, including transfers.
Lansdale to St. Louis bus services, operated by Greyhound USA, depart from Philadelphia Bus Station.
Lansdale to St. Louis train services, operated by Amtrak, depart from 30th Street Station.
The best way to get from Lansdale to St. Louis is to bus which takes 22h 45m and costs $140 - $240. Alternatively, you can train, which costs $290 - $1,300 and takes 27h 53m.
What companies run services between Lansdale, PA, USA and St. Louis, MO, USA?
Greyhound USA operates a bus from Philadelphia Bus Station to St Louis Bus Station 3 times a day. Tickets cost $140–230 and the journey takes 20h 50m. Alternatively, you can take a train from Lansdale to St. Louis via Jefferson Station, 11th St, Drexel Station at 30th St, 30th Street Station, Washington Union Station, and Chicago Union Station in around 27h 53m.
- Website
- southwest.com
Flights from Philadelphia International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 2h 23m
- When
- Every day
- Estimated price
- $140–800
Flights from Philadelphia International Airport to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 4h 16m
- When
- Monday to Wednesday
- Estimated price
- $160–800
Flights from Philadelphia International Airport to Lambert–St. Louis International Airport via Nashville
- Ave. Duration
- 4h 20m
- When
- Monday, Thursday, and Friday
- Estimated price
- $160–800
Flights from Baltimore-Washington International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 2h 15m
- When
- Every day
- Estimated price
- $110–650
Flights from Baltimore-Washington International Airport to Lambert–St. Louis International Airport via Pittsburgh
- Ave. Duration
- 3h 40m
- When
- Saturday, Tuesday, and Wednesday
- Estimated price
- $120–650
Flights from Baltimore-Washington International Airport to Lambert–St. Louis International Airport via Nashville
- Ave. Duration
- 4h 17m
- When
- Tuesday to Friday
- Estimated price
- $130–700
Flights from Baltimore-Washington International Airport to Lambert–St. Louis International Airport via Cleveland
- Ave. Duration
- 4h 20m
- When
- Tuesday and Wednesday
- Estimated price
- $120–650
Flights from Baltimore-Washington International Airport to Lambert–St. Louis International Airport via Detroit
- Ave. Duration
- 4h 25m
- When
- Monday, Thursday, and Friday
- Estimated price
- $120–650
Flights from Baltimore-Washington International Airport to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 4h 25m
- When
- Monday, Thursday, and Friday
- Estimated price
- $130–700
Flights from Ronald Reagan Washington National Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 2h 16m
- When
- Every day
- Estimated price
- $160–850
Flights from Ronald Reagan Washington National Airport to Lambert–St. Louis International Airport via Nashville
- Ave. Duration
- 4h 15m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $170–900
Flights from Ronald Reagan Washington National Airport to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 4h 15m
- When
- Tuesday and Wednesday
- Estimated price
- $170–900
- Phone
- +1 215-580-7800
- Website
- SEPTA
Train from Lansdale to Suburban Station
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- $3–5
- Website
- SEPTA
- Schedules at
- SEPTA: World Cup 2026
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Philadelphia Bus Station to St Louis Bus Station
- Ave. Duration
- 20h 50m
- Frequency
- 3 times a day
- Estimated price
- $140–230
- Website
- Greyhound
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Booking & Getting There
Lansdale to St. Louis bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
St. Louis is 1h behind Lansdale. It is currently 3:01 AM in Lansdale and 2:01 AM in St. Louis.
Lansdale to St. Louis train services, operated by Amtrak, arrive at Washington Union Station.
Yes, the driving distance between Lansdale to St. Louis is 878 miles. It takes approximately 15h 11m to drive from Lansdale to St. Louis.
There are 558+ hotels available in St. Louis.







