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How to get fromLargo to Florenceby plane, bus (Flixbus, Greyhound), bus, train, car, or bus (Greyhound)

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There are 6 ways to get from Largo to Florence by plane, bus (Flixbus, Greyhound), bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Florence Regional Airport

    best
    1. Fly from Tampa (TPA) to Florence Regional Airport (FLO)plane plane TPA - FLO
    6h 44m
    $82–395

  2. Bus

    1. Take the bus from Ulmerton Park N Ride Lot to Marion Transit Parking Lotbus bus 300
    2. Take the bus from Tampa Bus Station to Orlando Bus Stationbus bus
    3. Take the bus from Orlando Bus Station to Florence Bus Stationbus bus
    14h 20m

  3. Bus, train

    1. Take the bus from Ulmerton Park N Ride Lot to Marion Transit Parking Lotbus bus 300
    2. Take the train from Tampa to Kissimmee Amtrak Stationtrain train
    3. Take the train from Kissimmee Amtrak Station to Florence Stationtrain train
    15h 4m
    $190–396

  4. Drive 509.1 mi

    1. Drive from Largo to Florencecar car 509.1 mi
    9h 15m
    $93–135

  5. Fly to Myrtle Beach, bus

    1. Fly from Tampa (TPA) to Myrtle Beach (MYR)plane plane TPA - MYR
    2. Take the bus from Myrtle Beach to Florencebus bus
    6h 27m

  6. Bus via Jacksonville

    1. Take the bus from Tampa Bus Station to Jacksonvillebus bus
    2. Take the bus from Jacksonville to Sumter Bus Stopbus bus
    3. Take the bus from Sumter Bus Stop to Florence Bus Stationbus bus
    18h 41m

Tampa (TPA) to Florence Regional Airport (FLO) flights

Calendar14Weekly Planes
Duration5h 43mAverage Duration
Ticket$73Cheapest Price
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Questions & Answers

Map of how to get from Largo to Florence.ExpandLaunch map view
  • Distance: 482.2 mi
  • Duration: 6h 44m

What companies run services between Largo, FL, USA and Florence, SC, USA?

American Airlines flies from Tampa (TPA) to Florence Regional Airport (FLO) twice daily. Alternatively, you can take a bus from Ulmerton Park N Ride Lot to Florence Bus Station via Marion Transit Parking Lot, Tampa Bus Station, and Orlando Bus Station in around 14h 20m.

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