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How to get fromLargo to Panama Cityby car, plane, or bus

Find Transport to Panama City

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There are 6 ways to get from Largo to Panama City by car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive 332.9 mi

    best
    1. Drive from Largo to Panama Citycar car 332.9 mi
    6h 43m
    $61–88

  2. Fly Tampa to Northwest Florida Beaches International Airport

    1. Fly from Tampa (TPA) to Northwest Florida Beaches International Airport (ECP)plane plane TPA - ECP
    6h 3m
    $142–472

  3. Fly Tampa to Destin–Fort Walton Beach Airport, drive

    1. Fly from Tampa (TPA) to Destin–Fort Walton Beach Airport (VPS)plane plane TPA - VPS
    2. Drive from Destin–Fort Walton Beach Airport (VPS) to Panama Citycar car
    7h 9m
    $89–420

  4. Fly Tampa to Pensacola International Airport, drive

    1. Fly from Tampa (TPA) to Pensacola International Airport (PNS)plane plane TPA - PNS
    2. Drive from Pensacola-Airport-PNS to Panama Citycar car
    6h 4m
    $181–491

  5. Fly Tampa to Tallahassee, drive

    1. Fly from Tampa (TPA) to Tallahassee (TLH)plane plane TPA - TLH
    2. Drive from Tallahassee (TLH) to Panama Citycar car
    7h 33m
    $259–1,128

  6. Bus to Sarasota–Bradenton International Airport, fly to Northwest Florida Beaches International Airport

    1. Take the bus from Psta Grand Central Station to Desoto Station Parking For 12 & 203bus bus
    2. Fly from Sarasota–Bradenton International Airport (SRQ) to Northwest Florida Beaches International Airport (ECP)plane plane SRQ - ECP
    10h 11m
    $162–583

Tampa (TPA) to Northwest Florida Beaches International Airport (ECP) flights

Calendar86Weekly Planes
Duration5h 28mAverage Duration
Ticket$75Cheapest Price
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Questions & Answers

Map of how to get from Largo to Panama City.ExpandLaunch map view
  • Distance: 332.9 mi
  • Duration: 6h 43m

What companies run services between Largo, FL, USA and Panama City, FL, USA?

Delta, Southwest Airlines, and two other airlines fly from Tampa (TPA) to Northwest Florida Beaches International Airport (ECP) every 2 hours.

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Bus operators

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