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How to get fromLas Vegas to Defianceby plane, train, bus (Greyhound, Amtrak), bus, car, or taxi

Find Transport to Defiance

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There are 10 ways to get from Las Vegas to Defiance by plane, train, bus (Greyhound, Amtrak), bus, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Chicago Midway International Airport, train

    best
    1. Fly from Harry Reid International Airport (LAS) to Chicago Midway International Airport (MDW)plane plane LAS - MDW
    2. Take the train from Chicago Union Station to Bryan Amtrak Stationtrain train
    10h 6m
    $286–579

  2. Fly to Cleveland-Hopkins International Airport, train

    cheapest
    1. Fly from Harry Reid International Airport (LAS) to Cleveland-Hopkins International Airport (CLE)plane plane LAS - CLE
    2. Take the train from Cleveland Amtrak to Bryan Amtrak Stationtrain train
    10h 51m
    $242–467

  3. Bus

    1. Take the bus from Las Vegas Bus Terminal to Denver Union Stationbus bus
    2. Take the bus from Denver Union Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Union Station to Bryan Amtrak Stationbus bus
    44h 2m

  4. Bus, train (Amtrak)

    1. Take the bus from South Strip Transit Terminal to Kingman Stationbus bus
    2. Take the train from Kingman Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Bryan Amtrak Stationtrain train
    44h 53m

  5. Drive  1,924.7 mi

    1. Drive from Las Vegas to Defiancecar car 1,924.7 mi
    31h 7m
    $352–508

  6. Fly to Indianapolis, bus, taxi

    1. Fly from Harry Reid International Airport (LAS) to Indianapolis (IND)plane plane LAS - IND
    2. Take the bus from Indianapolis to Fort Waynebus bus
    3. Take the taxi from Fort Wayne to Defiancetaxi taxi
    10h 7m
    $306–718

  7. Fly to Chicago O'Hare International Airport, train

    1. Fly from Harry Reid International Airport (LAS) to Chicago O'Hare International Airport (ORD)plane plane LAS - ORD
    2. Take the train from Chicago Union Station to Bryan Amtrak Stationtrain train
    10h 27m
    $244–502

  8. Fly to John Glenn Columbus International Airport, bus, taxi

    1. Fly from Harry Reid International Airport (LAS) to John Glenn Columbus International Airport (CMH)plane plane LAS - CMH
    2. Take the bus from Wilson & Ferrell Shell Station - Columbus to Delphosbus bus
    3. Take the taxi from Delphos to Defiancetaxi taxi
    10h 11m
    $267–619

  9. Fly to Detroit, bus, train

    1. Fly from Harry Reid International Airport (LAS) to Detroit (DTW)plane plane LAS - DTW
    2. Take the bus from Dearborn to Toledobus bus
    3. Take the train from Toledo to Bryan Amtrak Stationtrain train
    10h 38m

  10. Fly to General Mitchell International Airport, train

    1. Fly from Harry Reid International Airport (LAS) to General Mitchell International Airport (MKE)plane plane LAS - MKE
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Bryan Amtrak Stationtrain train
    12h 25m
    $341–973

Harry Reid International Airport (LAS) to Chicago Midway International Airport (MDW) flights

Calendar50Weekly Planes
Duration3h 42mAverage Duration
Ticket$103Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Las Vegas to Defiance.ExpandLaunch map view
  • Distance: 1,732 mi
  • Duration: 10h 6m

What companies run services between Las Vegas, NV, USA and Defiance, OH, USA?

You can take a bus from Las Vegas Downtown to Defiance via Las Vegas Bus Terminal, Denver Union Station, Chicago Bus Station, Chicago Union Station, and Bryan Amtrak Station in around 44h 2m.

Airlines
Train operators
Bus operators
Other operators

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