There are 7 ways to get from Las Vegas to La Mesa by plane, tram, bus, train, car, bus (Flixbus), or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly, tram
best- Fly from Harry Reid International Airport (LAS) to San Diego International Airport (SAN)plane LAS - SAN
- Take the tram from Civic Center Station to La Mesa Blvd Stationtram
3h 45m$98–574Shuttle, bus
cheapest- Take a shuttle bus from 1100 S Main St. - Las Vegas to Escondido, CA - 796 W Valley PKWYLas Vegas
- Take the bus from Escondido Transit Center to Broadway & Park Blbus 235
7h 37m$57–94Bus, train
- Take the bus from Las Vegas to Downtown Los Angelesbus Las Vegas
- Take the train from Los Angeles to San Diego Old Town Transportation Centertrain Pacific Surfliner
8h 45m$101–187Bus, train via Victorville
- Take the bus from 129 E Fremount St to Victorville Transit Centerbus
- Take the train from Victorville Amtrak to Fullerton Amtrak Stationtrain
- Take the train from Fullerton Amtrak Station to San Diego Old Town Transportation Centertrain
10h 54m$103–184Drive 331.9 mi
- Drive from Las Vegas to La Mesacar 331.9 mi
5h 27m$61–88Bus via San Ysidro, CA
- Take the bus from Las Vegas to San Ysidro, CAbus Las Vegas
10h 4m$89–122Bus (Flixbus)
- Take the bus from Las Vegas Strip to San Diegobus FlixBus 2037
11h 39m$71–128
Las Vegas to La Mesa by bus, train, and tram
Questions & Answers
The cheapest way to get from Las Vegas to La Mesa is to drive which costs $60 - $90 and takes 5h 27m.
The fastest way to get from Las Vegas to La Mesa is to fly and tram which takes 3h 45m and costs $95 - $600.
No, there is no direct bus from Las Vegas to La Mesa. However, there are services departing from Las Vegas and arriving at University Av & Allison Av via San Ysidro Bus Terminal, Old Town Transit Center and University Av & College Av. The journey, including transfers, takes approximately 10h 4m.
The distance between Las Vegas and La Mesa is 283 miles. The road distance is 333.8 miles.
The best way to get from Las Vegas to La Mesa without a car is to bus and train which takes 8h 45m and costs $100 - $190.
It takes approximately 3h 45m to get from Las Vegas to La Mesa, including transfers.
Las Vegas to La Mesa bus services, operated by Tufesa, depart from Las Vegas station.
Las Vegas to La Mesa bus services, operated by Tufesa, arrive at San Ysidro, CA station.
Yes, the driving distance between Las Vegas to La Mesa is 334 miles. It takes approximately 5h 27m to drive from Las Vegas to La Mesa.
There are 2120+ hotels available in La Mesa.
What companies run services between Las Vegas, NV, USA and La Mesa, CA, USA?
Tufesa operates a bus from Las Vegas to San Ysidro, CA twice daily. Tickets cost $80–110 and the journey takes 7h.
- Website
- southwest.com
Flights from Harry Reid International Airport to San Diego International Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- $45–300
- Website
- alaskaair.com
Flights from Harry Reid International Airport to San Diego International Airport
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- $95–300
- Website
- flyfrontier.com
Flights from Harry Reid International Airport to San Diego International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- $80–260
- Website
- delta.com
Flights from Harry Reid International Airport to San Diego International Airport
- Ave. Duration
- 1h 17m
- When
- Every day
- Estimated price
- $45–300
- Phone
- +1 619-557-4555
- Website
- MTS
Tram from Civic Center Station to La Mesa Blvd Station
- Ave. Duration
- 39 min
- Frequency
- Every 20 minutes
- Estimated price
- $2–15
- Website
- MTS
- Schedules at
- MTS Schedules
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Los Angeles to San Diego Old Town Transportation Center
- Ave. Duration
- 2h 42m
- Frequency
- Hourly
- Estimated price
- $35–85
- Website
- Amtrak
Train from Victorville Amtrak to Fullerton Amtrak Station
- Ave. Duration
- 2h 47m
- Frequency
- Once daily
- Estimated price
- $28–60
- Website
- Amtrak
Train from Fullerton Amtrak Station to San Diego Old Town Transportation Center
- Ave. Duration
- 2h 11m
- Frequency
- Hourly
- Estimated price
- $30–65
- Website
- Amtrak
- Phone
- +1 833 766 3553
- Website
- Tufesa
Bus from Las Vegas to Downtown Los Angeles
- Ave. Duration
- 4h 15m
- Frequency
- Twice daily
- Estimated price
- $60–90
- Schedules at
- Tufesa
- Adult One way
- $60–90
Bus from Las Vegas to San Ysidro, CA
- Ave. Duration
- 7h
- Frequency
- Twice daily
- Estimated price
- $80–110
- Schedules at
- Tufesa
- Adult One way
- $80–110
- Phone
- +1 602-698-7800
- [email protected]
- Website
- Luxury Coach of America
Bus from 129 E Fremount St to Victorville Transit Center
- Ave. Duration
- 3h 25m
- Frequency
- 5 times a week
- Estimated price
- $42–45
- Schedules at
- Luxury Coach of America
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Las Vegas Strip to San Diego
- Ave. Duration
- 9h 20m
- Frequency
- Twice daily
- Estimated price
- $65–110
- Schedules at
- Flixbus USA
- [email protected]
- Website
- CBX Cross Border Express
Shuttle from 1100 S Main St. - Las Vegas to Escondido, CA - 796 W Valley PKWY
- Ave. Duration
- 5h 30m
- Frequency
- Once daily
- Estimated price
- $50–75
- Schedules at
- CBX Cross Border Express
- Phone
- +1 619-557-4555
- Website
- MTS
Bus from Escondido Transit Center to Broadway & Park Bl
- Ave. Duration
- 1h 8m
- Frequency
- Every 30 minutes
- Estimated price
- $2–5
- Website
- MTS
- Schedules at
- MTS Schedules
- One Way - Adult/Youth
- $2–5
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