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How to get fromLas Vegas to Mayo Clinicby plane, bus (Greyhound), bus, train, shuttle, or car

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There are 6 ways to get from Las Vegas to Mayo Clinic by plane, bus (Greyhound), bus, train, shuttle, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Rochester

    best
    1. Fly from Harry Reid International Airport (LAS) to Rochester (RST)plane plane LAS - RST
    8h 35m
    $115–544

  2. Bus

    1. Take the bus from Las Vegas to Cedar City, UTbus bus
    2. Take the bus from Cedar City to Denver Union Stationbus bus
    3. Take the bus from Denver Union Station to Des Moinesbus bus
    4. Take the bus from Des Moines to Saint Paul Union Depotbus bus
    5. Take the bus from St. Paul to Rochesterbus bus
    40h 4m
    $295–549

  3. Bus, train, shuttle

    1. Take the bus from South Strip Transit Terminal to Kingman Stationbus bus
    2. Take the train from Kingman Station to Kansas Citytrain train
    3. Take the bus from Kansas City to Owatonnabus bus
    4. Take a shuttle bus from Owatonna, MN to Rochestershuttle bus
    42h 14m
    $595–1,191

  4. Drive 1,574.4 mi

    1. Drive from Las Vegas to Mayo Cliniccar car 1,574.4 mi
    25h 35m
    $288–415

  5. Fly to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Harry Reid International Airport (LAS) to Minneapolis–Saint Paul International Airport (MSP)plane plane LAS - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    7h 5m
    $206–606

  6. Bus, train

    1. Take the bus from Las Vegas to Kingman, AZbus bus
    2. Take the train from Kingman Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Milwaukeetrain train
    4. Take the bus from Milwaukee to Rochesterbus bus
    47h 52m
    $734–1,519

Las Vegas to Mayo Clinic by bus and foot

Calendar5Weekly Services
Duration40h 4mAverage Duration
Ticket$295Cheapest Price
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Questions & Answers

Map of how to get from Las Vegas to Mayo Clinic.ExpandLaunch map view
  • Distance: 1,323.4 mi
  • Duration: 8h 35m

What companies run services between Las Vegas, NV, USA and Mayo Clinic, MN, USA?

Delta, American Airlines, and United Airlines fly from Harry Reid International Airport (LAS) to Rochester (RST) every 4 hours. Alternatively, you can take a bus from Las Vegas to Mayo Clinic via Cedar City, UT, Cedar City, Denver Union Station, Des Moines, St. Paul, and Rochester in around 40h 4m.

Airlines
Train operators
Bus operators

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