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How to get fromLatrobe to Chicagoby train, plane, train (Amtrak), bus, car, or bus (Greyhound, Flixbus)

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There are 7 ways to get from Latrobe to Chicago by train, plane, train (Amtrak), bus, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Johnstown-Cambria County Airport, fly to Chicago O'Hare International Airport

    best
    1. Take the train from Latrobe Amtrak to Johnstown Amtrak Stationtrain train
    2. Fly from Johnstown-Cambria County Airport (JST) to Chicago O'Hare International Airport (ORD)plane plane JST - ORD
    4h 37m
    $72–336

  2. Train (Amtrak)

    1. Take the train from Latrobe Amtrak to Pittsburgh Amtrak Stationtrain train Pennsylvanian
    2. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train Floridian
    11h 55m
    $152–335

  3. Train, bus

    1. Take the train from Latrobe Amtrak to Pittsburgh Amtrak Stationtrain train Pennsylvanian
    2. Take the bus from Pittsburgh Intermodal Station to Chicagobus bus FlixBus N2640
    13h 31m
    $89–160

  4. Drive 494.6 mi

    1. Drive from Latrobe to Chicagocar car 494.6 mi
    8h 19m
    $91–131

  5. Train, bus to Pittsburgh International Airport, fly to Chicago Midway International Airport

    1. Take the train from Latrobe Amtrak to Pittsburgh Amtrak Stationtrain train
    2. Take the bus from Liberty Ave + Tito Way to Pittsburgh International Airportbus bus
    3. Fly from Pittsburgh International Airport (PIT) to Chicago Midway International Airport (MDW)plane plane PIT - MDW
    5h 46m

  6. Train, bus to Pittsburgh International Airport, fly to Chicago O'Hare International Airport

    1. Take the train from Latrobe Amtrak to Pittsburgh Amtrak Stationtrain train
    2. Take the bus from Liberty Ave + Tito Way to Pittsburgh International Airportbus bus
    3. Fly from Pittsburgh International Airport (PIT) to Chicago O'Hare International Airport (ORD)plane plane PIT - ORD
    6h 13m

  7. Bus

    1. Take the bus from WCTA Transit Center to Grant St + 7th Ave FSbus bus 4 / ...
    2. Take the bus from Pittsburgh Intermodal Station to Chicago Bus Stationbus bus Greyhound US0164
    14h 47m
    $72–152

Latrobe to Chicago by train (Amtrak)

Calendar7Weekly Trains
Duration11h 55mAverage Duration
Ticket$152Cheapest Price
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Questions & Answers

Map of how to get from Latrobe to Chicago.ExpandLaunch map view
  • Distance: 545 mi
  • Duration: 4h 37m

What companies run services between Latrobe, PA, USA and Chicago, IL, USA?

You can take a train from Latrobe Amtrak to Chicago Union Station via Pittsburgh Amtrak Station in around 11h 55m. Alternatively, you can take a bus from Jefferson St + Spring St to Chicago Bus Station via WCTA Transit Center, Grant St + 7th Ave FS, and Pittsburgh Intermodal Station in around 14h 47m.

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