Rome2Rio

How to get fromLatrobe to Knoxvilleby train, plane, bus, or car

Find Transport to Knoxville

See all options

There are 7 ways to get from Latrobe to Knoxville by train, plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Johnstown-Cambria County Airport, fly to Mcghee Tyson Airport

    best
    1. Take the train from Latrobe Amtrak to Johnstown Amtrak Stationtrain train
    2. Fly from Johnstown-Cambria County Airport (JST) to Mcghee Tyson Airport (TYS)plane plane JST - TYS
    7h 15m
    $249–1,069

  2. Drive  483.7 mi

    cheapest
    1. Drive from Latrobe to Knoxvillecar car 483.7 mi
    8h 15m
    $86–124

  3. Train, bus via Farragut

    1. Take the train from Latrobe Amtrak to Ny Moynihan Train Hall At Penn Stationtrain train Pennsylvanian
    2. Take the bus from New York to Knoxvillebus bus Nyc
    22h 2m
    $401–588

  4. Train to Pittsburgh International Airport, fly to Mcghee Tyson Airport

    1. Take the train from Latrobe Amtrak to Pittsburgh Amtrak Stationtrain train
    2. Fly from Pittsburgh International Airport (PIT) to Mcghee Tyson Airport (TYS)plane plane PIT - TYS
    7h 46m
    $277–1,304

  5. Train to Pittsburgh International Airport, fly to Nashville, drive

    1. Take the train from Latrobe Amtrak to Pittsburgh Amtrak Stationtrain train
    2. Fly from Pittsburgh International Airport (PIT) to Nashville (BNA)plane plane PIT - BNA
    3. Drive from Nashville-Airport-BNA to Knoxvillecar car
    8h 7m
    $532–1,179

  6. Train, bus

    1. Take the train from Latrobe Amtrak to Ny Moynihan Train Hall At Penn Stationtrain train Pennsylvanian
    2. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    22h 6m
    $356–498

  7. Train, bus via Pittsburgh

    1. Take the train from Latrobe Amtrak to Pittsburgh Amtrak Stationtrain train
    2. Take the bus from Pittsburgh Intermodal Station to New York City Chinatownbus bus
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    28h 39m
    $191–259

Johnstown-Cambria County Airport (JST) to Mcghee Tyson Airport (TYS) flights

Calendar16Weekly Planes
Duration6h 39mAverage Duration
Ticket$165Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Latrobe to Knoxville.ExpandLaunch map view
  • Distance: 473.9 mi
  • Duration: 7h 15m

What companies run services between Latrobe, PA, USA and Knoxville, TN, USA?

There is no direct connection from Latrobe to Knoxville. However, you can take the train to Johnstown Amtrak Station, take the taxi to Johnstown-Cambria County Airport (JST) airport, fly to Mcghee Tyson Airport (TYS), then take the taxi to Knoxville. Alternatively, you can take a train from Latrobe Amtrak to Knoxville via Ny Moynihan Train Hall At Penn Station, 34 St-Herald Sq, East Broadway, New York, and Knoxville in around 22h 2m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides