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How to get fromLatrobe to St. Louisby train, plane, bus, train (Amtrak), or car

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There are 5 ways to get from Latrobe to St. Louis by train, plane, bus, train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Pittsburgh International Airport, fly

    best
    1. Take the train from Latrobe Amtrak to Pittsburgh Amtrak Stationtrain train
    2. Fly from Pittsburgh International Airport (PIT) to Lambert–St. Louis International Airport (STL)plane plane PIT - STL
    6h 8m
    $126–679

  2. Train, bus

    cheapest
    1. Take the train from Latrobe Amtrak to Pittsburgh Amtrak Stationtrain train Pennsylvanian
    2. Take the bus from Pittsburgh Intermodal Station to St Louis Bus Stationbus bus Greyhound US0421
    15h 4m
    $108–206

  3. Train (Amtrak)

    1. Take the train from Latrobe Amtrak to Pittsburgh Amtrak Stationtrain train
    2. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Louistrain train
    17h 41m
    $253–536

  4. Drive 629 mi

    1. Drive from Latrobe to St. Louiscar car 629 mi
    10h 50m
    $115–166

  5. Train to Johnstown-Cambria County Airport, fly

    1. Take the train from Latrobe Amtrak to Johnstown Amtrak Stationtrain train
    2. Fly from Johnstown-Cambria County Airport (JST) to Lambert–St. Louis International Airport (STL)plane plane JST - STL
    6h 39m
    $139–645

Latrobe to St. Louis by train and bus

Calendar7Weekly Services
Duration15h 4mAverage Duration
Ticket$108Cheapest Price
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Questions & Answers

Map of how to get from Latrobe to St. Louis.ExpandLaunch map view
  • Distance: 630.6 mi
  • Duration: 6h 8m

What companies run services between Latrobe, PA, USA and St. Louis, MO, USA?

You can take a train from Latrobe Amtrak to St. Louis via Pittsburgh Amtrak Station and Chicago Union Station in around 17h 41m.

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