There are 10 ways to get from Lausanne to Siena by train, bus, car, plane, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Lausanne to Domodossolatrain Ec
- Take the bus from Domodossola to Milano Centralebus Re4
- Take the train from Milano Centrale to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
8h 51mBus via Florence
cheapest- Take the bus from Lausanne to Florence Villa Constanza Bus Stationbus BlaBlaCar Bus
- Take the bus from Firenze Autostazione to Siena-Via Tozzibus 131R / ...
13h 42m€56–87Bus
- Take the bus from Lausanne to Florencebus FlixBus N1524
- Take the bus from Florence Villa Constanza Bus Station to Sienabus 1518 / ...
13h€64–97Drive 650.1 km
- Drive from Lausanne to Sienacar 650.1 km
7h 41m€117–169Train to Geneva International Airport, fly to Florence Peretola Airport, train
- Take the train from Lausanne to Genève-Aéroporttrain
- Fly from Geneva International Airport (GVA) to Florence Peretola Airport (FLR)plane GVA - FLR
- Take the train from Firenze S.M.N. to Sienatrain
8h 33m€123–306Train
- Take the train from Lausanne to Domodossolatrain Ec
- Take the train from Domodossola to Milano P.Garibalditrain Re
- Take the train from Milano P.Garibaldi to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
10h 11m€120–189Train to Zurich Airport, fly to Florence Peretola Airport, train
- Take the train from Lausanne to Zürich Flughafentrain
- Fly from Zurich Airport (ZRH) to Florence Peretola Airport (FLR)plane ZRH - FLR
- Take the train from Firenze S.M.N. to Sienatrain
8h 5m€177–396Train to Zurich Airport, fly to Bologna Guglielmo Marconi Airport, train
- Take the train from Lausanne to Zürich Flughafentrain
- Fly from Zurich Airport (ZRH) to Bologna Guglielmo Marconi Airport (BLQ)plane ZRH - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
8h 38m€174–436Train, bus, bus to Lyon–Saint Exupéry Airport, fly to Florence Peretola Airport
- Take the train from Lausanne to Genèvetrain
- Take the bus from Geneva to Annecybus
- Take the bus from Annecy - Bus Station to Lyon - St. Exupéry Airport T1 Bus Stopbus
- Fly from Lyon–Saint Exupéry Airport (LYS) to Florence Peretola Airport (FLR)plane LYS - FLR
- Take the train from Firenze S.M.N. to Sienatrain
9h 46m€81–342Train to Geneva International Airport, fly to Fiumicino International Airport, train
- Take the train from Lausanne to Genève-Aéroporttrain
- Fly from Geneva International Airport (GVA) to Fiumicino International Airport (FCO)plane GVA - FCO
- Take the train from Roma Termini to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
8h 55m€111–315
Geneva International Airport (GVA) to Florence Peretola Airport (FLR) flights
Comparing Your Travel Options
The cheapest way to get from Lausanne to Siena is to bus via Florence which costs €55 - €90 and takes 13h 42m.
The fastest way to get from Lausanne to Siena is to drive which takes 7h 41m and costs €110 - €170.
No, there is no direct bus from Lausanne to Siena. However, there are services departing from Lausanne and arriving at Siena via Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 13h.
No, there is no direct train from Lausanne to Siena. However, there are services departing from Lausanne and arriving at Siena via Domodossola, Milano P.Garibaldi and Firenze S.M.N.. The journey, including transfers, takes approximately 10h 11m.
The distance between Lausanne and Siena is 719 km. The road distance is 650.1 km.
The best way to get from Lausanne to Siena without a car is to train and bus which takes 8h 51m and costs .
It takes approximately 8h 51m to get from Lausanne to Siena, including transfers.
Lausanne to Siena bus services, operated by FlixBus, depart from Lausanne station.
Lausanne to Siena train services, operated by Swiss Federal Railways (SBB CFF FFS), depart from Lausanne station.
The best way to get from Lausanne to Siena is to bus which takes 13h and costs €60 - €100. Alternatively, you can train, which costs €120 - €190 and takes 10h 11m.
What companies run services between Lausanne, Switzerland and Siena, Italy?
You can take a bus from Lausanne to Siena via Florence Villa Constanza Bus Station in around 13h. Alternatively, you can take a train from Lausanne to Siena via Domodossola, Milano P.Garibaldi, and Firenze S.M.N. in around 10h 11m.
- Website
- swiss.com
Flights from Geneva International Airport to Florence Peretola Airport via Zurich Airport
- Ave. Duration
- 3h 46m
- When
- Every day
- Estimated price
- €85–260
Flights from Geneva International Airport to Florence Peretola Airport via Fiumicino International Airport
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- €95–270
Flights from Zurich Airport to Florence Peretola Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- €90–260
Flights from Zurich Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- €85–430
Flights from Geneva International Airport to Fiumicino International Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €75–190
- Website
- ita-airways.com
Flights from Geneva International Airport to Florence Peretola Airport via Fiumicino International Airport
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- €95–270
Flights from Geneva International Airport to Florence Peretola Airport via Zurich Airport
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- €85–260
Flights from Zurich Airport to Florence Peretola Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- €90–260
Flights from Zurich Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 20m
- When
- Every day
- Estimated price
- €160–550
Flights from Zurich Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- €85–430
Flights from Geneva International Airport to Fiumicino International Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €75–190
- Website
- lufthansa.com
Flights from Geneva International Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 55m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €180–650
Flights from Zurich Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 17m
- When
- Every day
- Estimated price
- €160–550
Flights from Lyon–Saint Exupéry Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- €70–390
- Website
- easyjet.com
Flights from Geneva International Airport to Fiumicino International Airport
- Ave. Duration
- 1h 31m
- When
- Friday, Sunday, Wednesday, Monday, Tuesday, and Thursday
- Estimated price
- €45–180
Flights from Geneva International Airport to Fiumicino International Airport via Nice
- Ave. Duration
- 3h 40m
- When
- Friday
- Estimated price
- €45–180
- Website
- volotea.com
Flights from Geneva International Airport to Florence Peretola Airport via Fiumicino International Airport
- Ave. Duration
- 6h 40m
- When
- Every day
- Estimated price
- €95–270
Flights from Lyon–Saint Exupéry Airport to Florence Peretola Airport
- Ave. Duration
- 1h 20m
- When
- Friday and Sunday
- Estimated price
- €26–200
Flights from Geneva International Airport to Fiumicino International Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €75–190
- Website
- airdolomiti.it
Flights from Zurich Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 15m
- When
- Friday
- Estimated price
- €160–550
Train from Lausanne to Domodossola
- Ave. Duration
- 2h
- Frequency
- 5 times a day
- Estimated price
- €55–80
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Lausanne to Genève-Aéroport
- Ave. Duration
- 52 min
- Frequency
- Every 20 minutes
- Estimated price
- €19–29
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Lausanne to Domodossola
- Ave. Duration
- 2h
- Frequency
- 5 times a day
- Estimated price
- €55–80
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Lausanne to Zürich Flughafen
- Ave. Duration
- 2h 37m
- Frequency
- Hourly
- Estimated price
- €65–100
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Lausanne to Zürich Flughafen
- Ave. Duration
- 2h 37m
- Frequency
- Hourly
- Estimated price
- €65–100
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Lausanne to Genève
- Ave. Duration
- 51 min
- Frequency
- Every 15 minutes
- Estimated price
- €18–26
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Lausanne to Genève-Aéroport
- Ave. Duration
- 52 min
- Frequency
- Every 20 minutes
- Estimated price
- €19–29
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 54m
- Frequency
- Hourly
- Estimated price
- €40–75
- Website
- Trenitalia Frecce
Train from Milano P.Garibaldi to Firenze S.M.N.
- Ave. Duration
- 2h 2m
- Frequency
- Every 3 hours
- Estimated price
- €40–75
- Website
- Trenitalia Frecce
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €12–22
- Website
- Trenitalia Frecce
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 1h 37m
- Frequency
- Every 30 minutes
- Estimated price
- €35–65
- Website
- Trenitalia Frecce
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 2h 41m
- Frequency
- 4 times a day
- Estimated price
- €35–60
- Website
- Italo Treno
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 46 min
- Frequency
- 5 times a day
- Estimated price
- €11–18
- Website
- Italo Treno
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 3h 42m
- Frequency
- Twice daily
- Estimated price
- €30–60
- Website
- Trenitalia Intercity
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- Twice daily
- Estimated price
- €9–18
- Website
- Trenitalia Intercity
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 3h 45m
- Frequency
- Twice daily
- Estimated price
- €27–55
- Website
- Trenitalia Intercity
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Domodossola to Milano P.Garibaldi
- Ave. Duration
- 2h 14m
- Frequency
- Every 2 hours
- Estimated price
- €14–20
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 35m
- Frequency
- 4 times a day
- Estimated price
- €11–15
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 3h 40m
- Frequency
- Every 3 hours
- Estimated price
- €30–45
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
- Phone
- +39 06 68475475
- [email protected]
- Website
- Trenitalia Eurocity
Train from Lausanne to Genève
- Ave. Duration
- 39 min
- Frequency
- Every 4 hours
- Estimated price
- €21–65
- Website
- Trenitalia Eurocity
- 1st Class
- €45–65
- 2nd Class
- €21–28
- Phone
- +39 02 7249 4494
- [email protected]
- Website
- Trenord
Bus from Domodossola to Milano Centrale
- Ave. Duration
- 1h 40m
- Frequency
- Every 2 hours
- Website
- Trenord
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Lausanne to Florence
- Ave. Duration
- 11h 10m
- Frequency
- Once daily
- Estimated price
- €55–90
- Website
- Flixbus
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 50 min
- Frequency
- Every 4 hours
- Estimated price
- €5–9
- Website
- Flixbus
Bus from Geneva to Annecy
- Ave. Duration
- 50 min
- Frequency
- Hourly
- Estimated price
- €3–6
- Website
- Flixbus
Bus from Annecy - Bus Station to Lyon - St. Exupéry Airport T1 Bus Stop
- Ave. Duration
- 1h 20m
- Frequency
- 3 times a day
- Estimated price
- €10–16
- Website
- Flixbus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Lausanne to Florence Villa Constanza Bus Station
- Ave. Duration
- 11h 40m
- Frequency
- 4 times a week
- Estimated price
- €45–80
- Website
- BlaBlaCar Bus
Bus from Geneva to Annecy
- Ave. Duration
- 50 min
- Frequency
- 5 times a day
- Estimated price
- €2–5
- Website
- BlaBlaCar Bus
Bus from Annecy - Bus Station to Lyon - St. Exupéry Airport T1 Bus Stop
- Ave. Duration
- 1h 20m
- Frequency
- Hourly
- Estimated price
- €8–14
- Website
- BlaBlaCar Bus
- Phone
- +39 800 142 424
- [email protected]
- Website
- at-bus.it
Bus from Firenze Autostazione to Siena-Via Tozzi
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €5–6
- Schedules at
- at-bus.it
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
5 incredible day trips from Florence by train
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
Booking & Getting There
Lausanne to Siena bus services, operated by FlixBus, arrive at Florence station.
Lausanne to Siena train services, operated by Swiss Federal Railways (SBB CFF FFS), arrive at Domodossola station.
Yes, the driving distance between Lausanne to Siena is 650 km. It takes approximately 7h 41m to drive from Lausanne to Siena.
Book your Lausanne to Siena train tickets online with Omio.
Book your Lausanne to Siena bus tickets online with Omio and FlixBus.
There are 2421+ hotels available in Siena.









































