There are 6 ways to get from Lee County to Jacksonville by bus (Flixbus), bus, train, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus (Flixbus)
best- Take the bus from Fort Myers Bus Stop to Orlando Bus Stationbus FlixBus 2421
- Take the bus from Orlando Bus Station to Jacksonvillebus FlixBus 2433 / ...
8h 40m$57–96Drive 296.2 mi
cheapest- Drive from Lee County to Jacksonvillecar 296.2 mi
5h 31m$55–79Bus, train
- Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus FlixBus 2421
- Take the train from Tampa to Jacksonvilletrain Floridian
10h 12m$100–199Bus to Fort Lauderdale–Hollywood International Airport, fly
- Take the bus from Fort Myers Bus Stop to Fort Lauderdale International Airportbus
- Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Jacksonville (JAX)plane FLL - JAX
6h 11m$142–787Bus to Miami International Airport, fly
- Take the bus from Fort Myers Bus Stop to Miami Airport Stationbus
- Fly from Miami International Airport (MIA) to Jacksonville (JAX)plane MIA - JAX
7h 8m$76–354Fly from Ft. Myers
- Fly from Ft. Myers (RSW) to Jacksonville (JAX)plane RSW - JAX
8h 31m$314–808
Lee County to Jacksonville by bus (Flixbus)
Questions & Answers
The cheapest way to get from Lee County to Jacksonville is to drive which costs $50 - $80 and takes 5h 31m.
The fastest way to get from Lee County to Jacksonville is to drive which takes 5h 31m and costs $50 - $80.
No, there is no direct bus from Lee County to Jacksonville. However, there are services departing from Fort Myers Bus Stop and arriving at Jacksonville via Orlando Bus Station. The journey, including transfers, takes approximately 8h 40m.
The distance between Lee County and Jacksonville is 362 miles. The road distance is 297.9 miles.
The best way to get from Lee County to Jacksonville without a car is to bus which takes 8h 40m and costs $55 - $100.
It takes approximately 8h 40m to get from Lee County to Jacksonville, including transfers.
Lee County to Jacksonville bus services, operated by Flixbus USA, depart from Fort Myers Bus Stop station.
The best way to get from Lee County to Jacksonville is to bus which takes 8h 40m and costs $55 - $100. Alternatively, you can fly, which costs $310 - $850 and takes 8h 31m.
Lee County to Jacksonville bus services, operated by Flixbus USA, arrive at Orlando Bus Station.
Yes, the driving distance between Lee County to Jacksonville is 298 miles. It takes approximately 5h 31m to drive from Lee County to Jacksonville.
What companies run services between Lee County, FL, USA and Jacksonville, FL, USA?
You can take a bus from Fort Myers Bus Stop to Jacksonville via Orlando Bus Station in around 8h 40m. Alternatively, Delta, American Airlines, and Southwest Airlines fly from Ft. Myers (RSW) to Jacksonville (JAX) every 3 hours.
- Website
- aa.com
Flights from Miami International Airport to Jacksonville
- Ave. Duration
- 1h 26m
- When
- Every day
- Estimated price
- $50–310
Flights from Ft. Myers to Jacksonville via Charlotte
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $110–600
- Website
- delta.com
Flights from Ft. Myers to Jacksonville via Atlanta
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- $100–550
- Website
- southwest.com
Flights from Ft. Myers to Jacksonville via Nashville
- Ave. Duration
- 5h 47m
- When
- Monday to Wednesday
- Estimated price
- $140–650
- Website
- flybreeze.com
Flights from Fort Lauderdale–Hollywood International Airport to Jacksonville
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- $110–750
- Website
- jetblue.com
Flights from Fort Lauderdale–Hollywood International Airport to Jacksonville
- Ave. Duration
- 1h 19m
- When
- Every day
- Estimated price
- $50–320
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Tampa to Jacksonville
- Ave. Duration
- 5h 24m
- Frequency
- Once daily
- Estimated price
- $75–160
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Fort Myers Bus Stop to Orlando Bus Station
- Ave. Duration
- 5h
- Frequency
- 4 times a day
- Estimated price
- $30–60
- Schedules at
- flixbus.com
Bus from Orlando Bus Station to Jacksonville
- Ave. Duration
- 2h 40m
- Frequency
- 5 times a day
- Estimated price
- $22–40
- Schedules at
- flixbus.com
Bus from Fort Myers Bus Stop to Tampa Bus Station
- Ave. Duration
- 2h 45m
- Frequency
- 4 times a day
- Estimated price
- $19–35
- Schedules at
- flixbus.com
Bus from Fort Myers Bus Stop to Fort Lauderdale International Airport
- Ave. Duration
- 2h 15m
- Frequency
- 3 times a day
- Estimated price
- $21–35
- Schedules at
- flixbus.com
Bus from Fort Myers Bus Stop to Miami Airport Station
- Ave. Duration
- 3h 5m
- Frequency
- 4 times a day
- Estimated price
- $25–45
- Schedules at
- flixbus.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Book your Lee County to Jacksonville bus tickets online with Omio and FlixBus.
There are 450+ hotels available in Jacksonville.




