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How to get fromLee's Summit to Tupeloby train, bus, car, plane, or bus (Greyhound)

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There are 8 ways to get from Lee's Summit to Tupelo by train, bus, car, plane, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Lee's Summit Station to St. Louistrain train
    2. Take the bus from St Louis Bus Station to Memphis Bus Stationbus bus
    3. Take the bus from Memphis Bus Station to Tupelobus bus
    13h 38m
    $156–302

  2. Drive 528.2 mi

    cheapest
    1. Drive from Lee's Summit to Tupelocar car 528.2 mi
    9h 40m
    $97–140

  3. Fly to Golden Triangle Regional Airport, drive

    1. Fly from Kansas City (MCI) to Golden Triangle Regional Airport (GTR)plane plane MCI - GTR
    2. Drive from Golden Triangle Regional Airport (GTR) to Tupelocar car
    8h 17m
    $131–617

  4. Bus

    1. Take the bus from Kansas City to Memphis Bus Stationbus bus Jefferson 121
    2. Take the bus from Memphis Bus Station to Tupelobus bus Greyhound US0610
    14h 26m
    $137–204

  5. Fly to Birmingham–Shuttlesworth International Airport, drive

    1. Fly from Kansas City (MCI) to Birmingham–Shuttlesworth International Airport (BHM)plane plane MCI - BHM
    2. Drive from Birmingham-Airport-BHM to Tupelocar car
    9h 1m
    $194–940

  6. Fly to Huntsville International Airport-Carl T Jones Field, drive

    1. Fly from Kansas City (MCI) to Huntsville International Airport-Carl T Jones Field (HSV)plane plane MCI - HSV
    2. Drive from Huntsville International Airport-Carl T Jones Field (HSV) to Tupelocar car
    9h 37m
    $163–735

  7. Fly to Tupelo Regional Airport

    1. Fly from Kansas City (MCI) to Tupelo Regional Airport (TUP)plane plane MCI - TUP
    7h 49m
    $114–568

  8. Fly to Memphis, bus

    1. Fly from Kansas City (MCI) to Memphis (MEM)plane plane MCI - MEM
    2. Take the bus from Memphis Bus Station to Tupelobus bus
    11h 26m
    $208–995

Kansas City (MCI) to Golden Triangle Regional Airport (GTR) flights

Calendar23Weekly Planes
Duration4h 43mAverage Duration
Ticket$128Cheapest Price
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Questions & Answers

Map of how to get from Lee's Summit to Tupelo.ExpandLaunch map view
  • Distance: 649.3 mi
  • Duration: 13h 38m

What companies run services between Lee's Summit, MO, USA and Tupelo, MS, USA?

You can take a bus from On 350 Hwy And Chipman Southbound to Tupelo via On 13Th Between Charlotte & Holmes Wb, Kansas City, Memphis Bus Station, and Tupelo in around 14h 26m. Alternatively, American Airlines, Corporate Flight Management Inc, and two other airlines fly from Kansas City (MCI) to Tupelo Regional Airport (TUP) 4 times a day.

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