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How to get fromLeesburg to Florida Keysby shuttle, plane, taxi, train, bus, car, or bus (Flixbus, Greyhound)

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There are 11 ways to get from Leesburg to Florida Keys by shuttle, plane, taxi, train, bus, car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Shuttle to Orlando, fly to Key West International Airport

    best
    1. Take a shuttle bus from Brownwood Hotel & Spa to MCO Airport - Terminal Ashuttle bus
    2. Fly from Orlando (MCO) to Key West International Airport (EYW)plane plane MCO - EYW
    6h 31m
    $210–827

  2. Drive 391.7 mi

    cheapest
    1. Drive from Leesburg to Florida Keyscar car 391.7 mi
    7h 56m
    $72–104

  3. Taxi, train, bus

    1. Take the taxi from Leesburg to Orlandotaxi taxi
    2. Take the train from Orlando to Miamitrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    10h 56m
    $231–416

  4. Shuttle to Tampa, fly to Key West International Airport

    1. Take a shuttle bus from Brownwood Hotel & Spa to Tampa International Airport - Red Terminalshuttle bus
    2. Fly from Tampa (TPA) to Key West International Airport (EYW)plane plane TPA - EYW
    7h 31m
    $220–587

  5. Taxi to Orlando Sanford, fly to Key West International Airport

    1. Take the taxi from Leesburg to Orlando-Sanford-Airport-SFBtaxi taxi
    2. Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane plane SFB - EYW
    5h 11m
    $213–463

  6. Shuttle to Orlando, fly to Miami International Airport, shuttle

    1. Take a shuttle bus from Brownwood Hotel & Spa to MCO Airport - Terminal Ashuttle bus
    2. Fly from Orlando (MCO) to Miami International Airport (MIA)plane plane MCO - MIA
    3. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle bus
    9h 4m
    $765–1,367

  7. Shuttle to Orlando, fly to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Take a shuttle bus from Brownwood Hotel & Spa to MCO Airport - Terminal Ashuttle bus
    2. Fly from Orlando (MCO) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane MCO - FLL
    3. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FLshuttle bus
    9h 31m
    $485–887

  8. Shuttle, line 300 bus to Saint Petersburg–Clearwater International Airport, fly to Key West International Airport, bus

    1. Take a shuttle bus from Brownwood Hotel & Spa to Tampa International Airport - Red Terminalshuttle bus
    2. Take the bus from Tpa Rental Car Facility to Psta 34Th St Complex - Shelter - Dbus bus
    3. Fly from Saint Petersburg–Clearwater International Airport (PIE) to Key West International Airport (EYW)plane plane PIE - EYW
    4. Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodgebus bus
    9h 26m
    $191–443

  9. Bus

    1. Take the bus from Orlando to Miami Airport Stationbus bus FlixBus 2411 / ...
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus Greyhound US0720s
    14h 31m
    $115–179

  10. Bus, train

    1. Take the bus from Wildwood Amtrak Station to Lakelandbus bus
    2. Take the train from Lakeland to West Palm Beach Amtrak Stationtrain train
    3. Take the train from West Palm Beach Station to Miami Airport Stationtrain train
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    14h 55m
    $132–239

  11. Bus, shuttle

    1. Take the bus from Wildwood to Miamibus bus Houston
    2. Take a shuttle bus from Miami, FL - International Airport to Summerland Key - Mote Marine Labshuttle bus To the Keys
    14h 59m
    $266–329

Orlando (MCO) to Key West International Airport (EYW) flights

Calendar10Weekly Planes
Duration2h 12mAverage Duration
Ticket$37Cheapest Price
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Questions & Answers

Map of how to get from Leesburg to Florida Keys.ExpandLaunch map view
  • Distance: 360.7 mi
  • Duration: 6h 31m

What companies run services between Leesburg, FL, USA and Florida Keys, FL, USA?

You can take a vehicle from Leesburg to Florida Keys via Holly St & N Orange Blossom Trl, Apopka Superstop Bay-A, N Garland Ave & W Amelia St, Florida Mall, Orlando, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 14h 31m.

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