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How to get fromLeesburg to Knoxvilleby taxi, plane, train, bus, bus (Amtrak, Flixbus), car, or shuttle

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There are 7 ways to get from Leesburg to Knoxville by taxi, plane, train, bus, bus (Amtrak, Flixbus), car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Orlando Sanford, fly to Mcghee Tyson Airport

    best
    1. Take the taxi from Leesburg to Orlando-Sanford-Airport-SFBtaxi taxi
    2. Fly from Orlando Sanford (SFB) to Mcghee Tyson Airport (TYS)plane plane SFB - TYS
    2h 54m
    $276–889

  2. Drive 593 mi

    cheapest
    1. Drive from Leesburg to Knoxvillecar car 593 mi
    10h 15m
    $109–157

  3. Taxi, train, bus

    1. Take the taxi from Leesburg to Delandtaxi taxi
    2. Take the train from Deland to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    35h 42m
    $575–1,028

  4. Bus

    1. Take the bus from Wildwood Amtrak Station to Jacksonvillebus bus
    2. Take the bus from Jacksonville to New York City Chinatownbus bus
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    41h 52m
    $328–482

  5. Shuttle to Orlando, fly to Mcghee Tyson Airport

    1. Take a shuttle bus from Brownwood Hotel & Spa to MCO Airport - Terminal Ashuttle bus
    2. Fly from Orlando (MCO) to Mcghee Tyson Airport (TYS)plane plane MCO - TYS
    4h 21m
    $228–803

  6. Taxi to Orlando Sanford, fly to Asheville Regional Airport, drive

    1. Take the taxi from Leesburg to Orlando-Sanford-Airport-SFBtaxi taxi
    2. Fly from Orlando Sanford (SFB) to Asheville Regional Airport (AVL)plane plane SFB - AVL
    3. Drive from Asheville-Airport-AVL to Knoxvillecar car
    4h 50m
    $178–504

  7. Bus, train

    1. Take the bus from LX10149 Citizens Blvd & Citizens Blvd to LX50001 FDOT Park N Ridebus bus 27
    2. Take the train from Kissimmee Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York to Knoxvillebus bus Nyc
    41h 48m
    $536–1,006

Orlando Sanford (SFB) to Mcghee Tyson Airport (TYS) flights

Calendar11Weekly Planes
Duration1h 38mAverage Duration
Ticket$120Cheapest Price
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Questions & Answers

Map of how to get from Leesburg to Knoxville.ExpandLaunch map view
  • Distance: 567.3 mi
  • Duration: 2h 54m

What companies run services between Leesburg, FL, USA and Knoxville, TN, USA?

You can take a vehicle from Leesburg to Knoxville Station Hall of Fame via Wildwood Amtrak Station, Jacksonville, Amtrak Station, JRTC Bay H, Jacksonville, New York, NY, Knoxville, TN, Walmart, and Charlie Haun WB Aft Washington PK in around 41h 52m.

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