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How to get fromLeesburg to St. Louisby shuttle, plane, taxi, bus, car, bus (Flixbus, Greyhound), or bus (Amtrak, Flixbus, Greyhound)

Find Transport to St. Louis

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There are 9 ways to get from Leesburg to St. Louis by shuttle, plane, taxi, bus, car, bus (Flixbus, Greyhound), or bus (Amtrak, Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Shuttle to Orlando, fly to Lambert–St. Louis International Airport

    best
    1. Take a shuttle bus from Brownwood Hotel & Spa to MCO Airport - Terminal Ashuttle bus
    2. Fly from Orlando (MCO) to Lambert–St. Louis International Airport (STL)plane plane MCO - STL
    5h 32m
    $246–456

  2. Drive 946.7 mi

    cheapest
    1. Drive from Leesburg to St. Louiscar car 946.7 mi
    15h 52m
    $173–250

  3. Taxi, bus

    1. Take the taxi from Leesburg to Ocala, FLtaxi taxi
    2. Take the bus from Ocala, FL to University of Florida - 1956 Gale Lemerand Drbus bus
    3. Take the bus from Gainesville to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    22h 35m
    $237–390

  4. Shuttle to Tampa, fly to Lambert–St. Louis International Airport

    1. Take a shuttle bus from Brownwood Hotel & Spa to Tampa International Airport - Red Terminalshuttle bus
    2. Fly from Tampa (TPA) to Lambert–St. Louis International Airport (STL)plane plane TPA - STL
    6h 24m
    $496–2,106

  5. Taxi to Orlando Sanford, fly to Midamerica St. Louis Airport

    1. Take the taxi from Leesburg to Orlando-Sanford-Airport-SFBtaxi taxi
    2. Fly from Orlando Sanford (SFB) to Midamerica St. Louis Airport (BLV)plane plane SFB - BLV
    4h 25m
    $207–571

  6. Bus to Sarasota–Bradenton International Airport, fly to Lambert–St. Louis International Airport

    1. Take the bus from Wildwood to Bradentonbus bus
    2. Fly from Sarasota–Bradenton International Airport (SRQ) to Lambert–St. Louis International Airport (STL)plane plane SRQ - STL
    8h 40m
    $248–911

  7. Bus to Jacksonville, fly to Lambert–St. Louis International Airport

    1. Take the bus from Wildwood Amtrak Station to Jacksonvillebus bus
    2. Fly from Jacksonville (JAX) to Lambert–St. Louis International Airport (STL)plane plane JAX - STL
    10h 33m
    $203–763

  8. Bus

    1. Take the bus from Orlando Bus Station to Atlanta Bus Stationbus bus FlixBus N2401 / ...
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus Greyhound US0186
    23h 40m
    $209–370

  9. Bus via Jacksonville

    1. Take the bus from Wildwood Amtrak Station to Jacksonvillebus bus
    2. Take the bus from Jacksonville to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    25h 37m
    $219–387

Orlando (MCO) to Lambert–St. Louis International Airport (STL) flights

Calendar66Weekly Planes
Duration3h 2mAverage Duration
Ticket$113Cheapest Price
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Questions & Answers

Map of how to get from Leesburg to St. Louis.ExpandLaunch map view
  • Distance: 965.8 mi
  • Duration: 5h 32m

What companies run services between Leesburg, FL, USA and St. Louis, MO, USA?

You can take a vehicle from Leesburg to St Louis Bus Station via Holly St & N Orange Blossom Trl, Apopka Superstop Bay-A, N Garland Ave & W Amelia St, N John Young Pkwy & Business Center Blvd, Orlando Bus Station, and Atlanta Bus Station in around 23h 40m.

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