Rome2Rio

How to get fromLeesburg to Winston-Salemby shuttle, plane, bus, bus (Flixbus, Greyhound), taxi, train, car, or bus (Amtrak, Greyhound)

Find Transport to Winston-Salem

See all options

There are 11 ways to get from Leesburg to Winston-Salem by shuttle, plane, bus, bus (Flixbus, Greyhound), taxi, train, car, or bus (Amtrak, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Shuttle to Orlando, fly to Charlotte Douglas International Airport, bus

    best
    1. Take a shuttle bus from Brownwood Hotel & Spa to MCO Airport - Terminal Ashuttle bus
    2. Fly from Orlando (MCO) to Charlotte Douglas International Airport (CLT)plane plane MCO - CLT
    3. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    7h 26m
    $174–469

  2. Drive 579.3 mi

    cheapest
    1. Drive from Leesburg to Winston-Salemcar car 579.3 mi
    10h 25m
    $106–153

  3. Bus

    1. Take the bus from Orlando Bus Station to Charlotte Bus Stationbus bus FlixBus 2433
    2. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus Greyhound US0670
    16h 10m
    $146–250

  4. Taxi, train, bus

    1. Take the taxi from Leesburg to Delandtaxi taxi
    2. Take the train from Deland to Carytrain train
    3. Take the train from Cary to Greensborotrain train
    4. Take the bus from Greensboro Bus Stop to Winston Salem(Trans Center)bus bus
    17h 21m
    $304–563

  5. Taxi to Daytona Beach International Airport, fly to Charlotte Douglas International Airport, bus

    1. Take the taxi from Leesburg to Amelia Super Stoptaxi taxi
    2. Fly from Daytona Beach International Airport (DAB) to Charlotte Douglas International Airport (CLT)plane plane DAB - CLT
    3. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    7h 32m
    $230–875

  6. Shuttle to Orlando, fly to Raleigh-Durham International Airport, bus

    1. Take a shuttle bus from Brownwood Hotel & Spa to MCO Airport - Terminal Ashuttle bus
    2. Fly from Orlando (MCO) to Raleigh-Durham International Airport (RDU)plane plane MCO - RDU
    3. Take the bus from Durham to Winston Salem(Trans Center)bus bus
    8h 9m
    $151–402

  7. Taxi to Orlando Sanford, fly to Asheville Regional Airport, bus

    1. Take the taxi from Leesburg to Orlando-Sanford-Airport-SFBtaxi taxi
    2. Fly from Orlando Sanford (SFB) to Asheville Regional Airport (AVL)plane plane SFB - AVL
    3. Take the bus from Asheville, NC to Winston Salem(Trans Center)bus bus
    7h 39m
    $179–505

  8. Taxi, bus to Gainesville Regional Airport, fly to Charlotte Douglas International Airport, bus

    1. Take the taxi from Leesburg to Ocala, FLtaxi taxi
    2. Take the bus from Ocala, FL to University of Florida - 1956 Gale Lemerand Drbus bus
    3. Fly from Gainesville Regional Airport (GNV) to Charlotte Douglas International Airport (CLT)plane plane GNV - CLT
    4. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    9h 28m
    $193–657

  9. Taxi to Orlando Sanford, fly to Concord, train

    1. Take the taxi from Leesburg to Orlando-Sanford-Airport-SFBtaxi taxi
    2. Fly from Orlando Sanford (SFB) to Concord (USA)plane plane SFB - USA
    3. Take the train from Kannapolis to High Pointtrain train
    6h 31m
    $198–394

  10. Bus via Jacksonville

    1. Take the bus from Wildwood Amtrak Station to Jacksonvillebus bus
    2. Take the bus from Jacksonville to Camdenbus bus
    3. Take the bus from Camden to Charlotte Bus Stationbus bus
    4. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    18h 22m
    $147–270

  11. Bus, train

    1. Take the bus from LX10149 Citizens Blvd & Citizens Blvd to LX50001 FDOT Park N Ridebus bus 27
    2. Take the train from Kissimmee Amtrak Station to Fayetteville Amtrak Stationtrain train
    3. Take the bus from Fayetteville Bus Station to Winston Salem(Trans Center)bus bus
    22h 27m
    $206–428

Leesburg to Winston-Salem by bus and train

Calendar7Weekly Services
Duration22h 27mAverage Duration
Ticket$206Cheapest Price
See schedules

Questions & Answers

Map of how to get from Leesburg to Winston-Salem.ExpandLaunch map view
  • Distance: 624.8 mi
  • Duration: 7h 26m

What companies run services between Leesburg, FL, USA and Winston-Salem, NC, USA?

You can take a vehicle from Leesburg to Winston Salem(Trans Center) via Holly St & N Orange Blossom Trl, Apopka Superstop Bay-A, N Garland Ave & W Amelia St, N John Young Pkwy & Business Center Blvd, Orlando Bus Station, and Charlotte Bus Station in around 16h 10m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound