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How to get fromLewes to Buffaloby shuttle, plane, bus, train, bus (Greyhound, Flixbus), or car

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There are 8 ways to get from Lewes to Buffalo by shuttle, plane, bus, train, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Shuttle to Philadelphia International Airport, fly to Buffalo Niagara International Airport

    best
    1. Take a shuttle bus from Lewes Transit Center to Philadelphia Airportshuttle bus
    2. Fly from Philadelphia International Airport (PHL) to Buffalo Niagara International Airport (BUF)plane plane PHL - BUF
    6h 43m
    $169–751

  2. Drive 437 mi

    cheapest
    1. Drive from Lewes to Buffalocar car 437 mi
    8h 58m
    $80–116

  3. Bus, train

    1. Take the bus from Lewes Transit Center to Wilmington Tcbus bus 305
    2. Take the train from Wilmington to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train
    14h 59m
    $173–949

  4. Bus via Wilmington

    1. Take the bus from Lewes Transit Center to Wilmington Tcbus bus 305
    2. Take the bus from Wilmington Bus Station to Newark Penn Stationbus bus
    3. Take the bus from Newark Penn Station to Buffalobus bus
    15h 33m
    $83–164

  5. Bus, train to Baltimore-Washington International Airport, fly to Buffalo Niagara International Airport

    1. Take the bus from Lewes Transit Center to Wilmington Tcbus bus
    2. Take the train from Wilmington to BWI Thurgood Marshalltrain train
    3. Fly from Baltimore-Washington International Airport (BWI) to Buffalo Niagara International Airport (BUF)plane plane BWI - BUF
    7h 56m
    $107–1,188

  6. Shuttle to Philadelphia International Airport, fly to Rochester, bus

    1. Take a shuttle bus from Lewes Transit Center to Philadelphia Airportshuttle bus
    2. Fly from Philadelphia International Airport (PHL) to Rochester (ROC)plane plane PHL - ROC
    3. Take the bus from Rochester Bus Stop to Buffalobus bus
    8h 21m
    $201–816

  7. Bus, train to Ronald Reagan Washington National Airport, fly to Buffalo Niagara International Airport

    1. Take the bus from Lewes Transit Center to Wilmington Tcbus bus
    2. Take the train from Wilmington to Washington Union Stationtrain train
    3. Fly from Ronald Reagan Washington National Airport (DCA) to Buffalo Niagara International Airport (BUF)plane plane DCA - BUF
    8h 48m
    $158–1,495

  8. Bus

    1. Take the bus from Dewey Beach, DE to Penn Station NYbus bus Dewey Beach
    2. Take the bus from New York to Buffalobus bus Adt N816 / ...
    16h 12m
    $98–340

Lewes to Buffalo by bus and train

Calendar12Weekly Services
Duration14h 59mAverage Duration
Ticket$173Cheapest Price
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Questions & Answers

Map of how to get from Lewes to Buffalo.ExpandLaunch map view
  • Distance: 399.9 mi
  • Duration: 6h 43m

What companies run services between Lewes, DE, USA and Buffalo, NY, USA?

You can take a bus from Market St @ 2Nd St to Buffalo via Lewes Transit Center, Wilmington Tc, Wilmington Bus Station, and Newark Penn Station in around 15h 33m.

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