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How to get fromLewes to Chicagoby shuttle, plane, bus, train, bus (Greyhound), or car

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There are 10 ways to get from Lewes to Chicago by shuttle, plane, bus, train, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Shuttle to Philadelphia International Airport, fly to Chicago Midway International Airport

    best
    1. Take a shuttle bus from Lewes Transit Center to Philadelphia Airportshuttle bus
    2. Fly from Philadelphia International Airport (PHL) to Chicago Midway International Airport (MDW)plane plane PHL - MDW
    6h 58m
    $214–447

  2. Bus, train to Baltimore-Washington International Airport, fly to Chicago O'Hare International Airport

    cheapest
    1. Take the bus from Lewes Transit Center to Wilmington Tcbus bus
    2. Take the train from Wilmington to BWI Thurgood Marshalltrain train
    3. Fly from Baltimore-Washington International Airport (BWI) to Chicago O'Hare International Airport (ORD)plane plane BWI - ORD
    8h 55m
    $92–974

  3. Bus, train via Washington

    1. Take the bus from Lewes Transit Center to Wilmington Tcbus bus 305
    2. Take the train from Wilmington to Washington Union Stationtrain train
    3. Take the train from Washington Union Station to Chicago Union Stationtrain train
    23h 52m
    $282–1,209

  4. Bus

    1. Take the bus from Lewes Transit Center to Wilmington Tcbus bus 305
    2. Take the bus from Wilmington Bus Station to Baltimore Downtown Bus Stationbus bus
    3. Take the bus from Baltimore Downtown Bus Station to Chicago Bus Stationbus bus
    25h 8m
    $127–250

  5. Drive 789.9 mi

    1. Drive from Lewes to Chicagocar car 789.9 mi
    14h 7m
    $145–209

  6. Shuttle to Philadelphia International Airport, fly to Chicago O'Hare International Airport

    1. Take a shuttle bus from Lewes Transit Center to Philadelphia Airportshuttle bus
    2. Fly from Philadelphia International Airport (PHL) to Chicago O'Hare International Airport (ORD)plane plane PHL - ORD
    7h 27m
    $194–297

  7. Bus, train to Baltimore-Washington International Airport, fly to Chicago Midway International Airport

    1. Take the bus from Lewes Transit Center to Wilmington Tcbus bus
    2. Take the train from Wilmington to BWI Thurgood Marshalltrain train
    3. Fly from Baltimore-Washington International Airport (BWI) to Chicago Midway International Airport (MDW)plane plane BWI - MDW
    8h 28m
    $147–914

  8. Bus, train to Ronald Reagan Washington National Airport, fly to Chicago Midway International Airport

    1. Take the bus from Lewes Transit Center to Wilmington Tcbus bus
    2. Take the train from Wilmington to Washington Union Stationtrain train
    3. Fly from Ronald Reagan Washington National Airport (DCA) to Chicago Midway International Airport (MDW)plane plane DCA - MDW
    9h 9m
    $148–1,271

  9. Bus, train to Ronald Reagan Washington National Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Lewes Transit Center to Wilmington Tcbus bus
    2. Take the train from Wilmington to Washington Union Stationtrain train
    3. Fly from Ronald Reagan Washington National Airport (DCA) to Chicago O'Hare International Airport (ORD)plane plane DCA - ORD
    9h 32m
    $158–1,521

  10. Bus, train

    1. Take the bus from Lewes Transit Center to Wilmington Tcbus bus 305
    2. Take the train from Wilmington to Chicago Union Stationtrain train Cardinal
    30h 53m
    $337–709

Lewes to Chicago by bus and train

Calendar10Weekly Services
Duration23h 52mAverage Duration
Ticket$282Cheapest Price
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Questions & Answers

Map of how to get from Lewes to Chicago.ExpandLaunch map view
  • Distance: 784.7 mi
  • Duration: 6h 58m

What companies run services between Lewes, DE, USA and Chicago, IL, USA?

You can take a bus from Market St @ 2Nd St to Chicago Bus Station via Lewes Transit Center, Wilmington Tc, Wilmington Bus Station, and Baltimore Downtown Bus Station in around 25h 8m.

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