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How to get fromLewes to Columbiaby taxi, plane, bus, train, car, shuttle, or bus (Greyhound, Flixbus)

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There are 6 ways to get from Lewes to Columbia by taxi, plane, bus, train, car, shuttle, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Salisbury–Ocean City–Wicomico Regional Airport, fly

    best
    1. Take the taxi from Lewes to Salisbury–Ocean City–Wicomico Regional Airport (SBY)taxi taxi
    2. Fly from Salisbury–Ocean City–Wicomico Regional Airport (SBY) to Columbia (CAE)plane plane SBY - CAE
    6h 6m
    $201–536

  2. Bus via Raleigh

    cheapest
    1. Take the bus from Lewes Transit Center to Wilmington Tcbus bus 305
    2. Take the bus from Wilmington Bus Station to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to Raleigh Bus Stationbus bus
    4. Take the bus from Raleigh Bus Station to Sumter Bus Stopbus bus
    5. Take the bus from James E Clyburn Intermodal Transportation Center to Assembly Gervais Northbus bus 44
    20h 10m
    $88–171

  3. Bus, train

    1. Take the bus from Lewes Transit Center to Wilmington Tcbus bus 305
    2. Take the train from Wilmington to Washington Union Stationtrain train
    3. Take the train from Washington Union Station to Columbia Stationtrain train
    16h 41m
    $182–989

  4. Bus

    1. Take the bus from Lewes Transit Center to Wilmington Tcbus bus 305
    2. Take the bus from Wilmington, DE - 3 W 4th St to Baltimore, MDbus bus
    3. Take the bus from Baltimore, MD to Columbia, SCbus bus Nyc
    17h 52m
    $99–143

  5. Drive 538.2 mi

    1. Drive from Lewes to Columbiacar car 538.2 mi
    10h 22m
    $99–142

  6. Shuttle to Philadelphia International Airport, fly

    1. Take a shuttle bus from Lewes Transit Center to Philadelphia Airportshuttle bus
    2. Fly from Philadelphia International Airport (PHL) to Columbia (CAE)plane plane PHL - CAE
    7h 43m
    $154–554

Lewes to Columbia by bus and train

Calendar7Weekly Services
Duration16h 41mAverage Duration
Ticket$182Cheapest Price
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Questions & Answers

Map of how to get from Lewes to Columbia.ExpandLaunch map view
  • Distance: 486.1 mi
  • Duration: 6h 6m

What companies run services between Lewes, DE, USA and Columbia, SC, USA?

You can take a bus from Market St @ 2Nd St to Sumter Laurel South via Lewes Transit Center, Wilmington Tc, Wilmington, DE - 3 W 4th St, Baltimore, MD, Columbia, SC, and Broad Marley South in around 17h 52m.

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