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How to get fromLewes to Durhamby shuttle, plane, bus, train, car, car ferry, or bus (Greyhound, Flixbus)

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There are 8 ways to get from Lewes to Durham by shuttle, plane, bus, train, car, car ferry, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Shuttle to Philadelphia International Airport, fly

    best
    1. Take a shuttle bus from Lewes Transit Center to Philadelphia Airportshuttle bus
    2. Fly from Philadelphia International Airport (PHL) to Raleigh-Durham International Airport (RDU)plane plane PHL - RDU
    7h 13m
    $153–448

  2. Drive 338.2 mi

    cheapest
    1. Drive from Lewes to Durhamcar car 338.2 mi
    7h 23m
    $62–90

  3. Bus

    1. Take the bus from Lewes Transit Center to Wilmington Tcbus bus 305
    2. Take the bus from Wilmington, DE - 3 W 4th St to Baltimore, MDbus bus
    3. Take the bus from Baltimore, MD to Durhambus bus Nyc
    12h 25m
    $72–106

  4. Bus, train

    1. Take the bus from Lewes Transit Center to Wilmington Tcbus bus 305
    2. Take the train from Wilmington to Washington Union Stationtrain train
    3. Take the train from Washington Union Station to Durham Amtrak Stationtrain train
    12h 54m
    $132–879

  5. Car ferry, drive to Atlantic City International Airport, fly

    1. Take the car ferry from Lewes, DE to Cape May, NJcarferry car ferry
    2. Drive from Cape May, NJ to Atlantic City International Airport (ACY)car car
    3. Fly from Atlantic City International Airport (ACY) to Raleigh-Durham International Airport (RDU)plane plane ACY - RDU
    6h 13m
    $162–1,026

  6. Bus, train to Baltimore-Washington International Airport, fly

    1. Take the bus from Lewes Transit Center to Wilmington Tcbus bus
    2. Take the train from Wilmington to BWI Thurgood Marshalltrain train
    3. Fly from Baltimore-Washington International Airport (BWI) to Raleigh-Durham International Airport (RDU)plane plane BWI - RDU
    8h 29m
    $211–965

  7. Bus, train to Ronald Reagan Washington National Airport, fly

    1. Take the bus from Lewes Transit Center to Wilmington Tcbus bus
    2. Take the train from Wilmington to Washington Union Stationtrain train
    3. Fly from Ronald Reagan Washington National Airport (DCA) to Raleigh-Durham International Airport (RDU)plane plane DCA - RDU
    9h 13m
    $592–1,872

  8. Bus via Washington

    1. Take the bus from Lewes Transit Center to Wilmington Tcbus bus 305
    2. Take the bus from Wilmington Bus Station to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to Durhambus bus
    13h 23m
    $63–129

Lewes to Durham by bus and train

Calendar7Weekly Services
Duration12h 54mAverage Duration
Ticket$132Cheapest Price
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Questions & Answers

Map of how to get from Lewes to Durham.ExpandLaunch map view
  • Distance: 461.7 mi
  • Duration: 7h 13m

What companies run services between Lewes, DE, USA and Durham, NC, USA?

You can take a bus from Market St @ 2Nd St to Durham via Lewes Transit Center, Wilmington Tc, Wilmington, DE - 3 W 4th St, and Baltimore, MD in around 12h 25m.

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