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How to get fromLewes to Florenceby taxi, plane, bus, train, bus (Greyhound, Flixbus), or car

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There are 4 ways to get from Lewes to Florence by taxi, plane, bus, train, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi, fly

    best
    1. Take the taxi from Lewes to Salisbury–Ocean City–Wicomico Regional Airport (SBY)taxi taxi
    2. Fly from Salisbury–Ocean City–Wicomico Regional Airport (SBY) to Florence Regional Airport (FLO)plane plane SBY - FLO
    5h 36m
    $209–547

  2. Bus

    cheapest
    1. Take the bus from Lewes Transit Center to Wilmington Tcbus bus 305
    2. Take the bus from Wilmington Bus Station to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to Raleigh Bus Stationbus bus
    4. Take the bus from Raleigh Bus Station to Florence Bus Stationbus bus
    16h 22m
    $80–164

  3. Bus, train

    1. Take the bus from Lewes Transit Center to Wilmington Tcbus bus 305
    2. Take the train from Wilmington to Washington Union Stationtrain train
    3. Take the train from Washington Union Station to Florence Stationtrain train
    13h 52m
    $152–929

  4. Drive 459.6 mi

    1. Drive from Lewes to Florencecar car 459.6 mi
    9h 6m
    $84–122

Lewes to Florence by bus and train

Calendar12Weekly Services
Duration13h 52mAverage Duration
Ticket$152Cheapest Price
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Questions & Answers

Map of how to get from Lewes to Florence.ExpandLaunch map view
  • Distance: 413.9 mi
  • Duration: 5h 36m

What companies run services between Lewes, DE, USA and Florence, SC, USA?

You can take a bus from Market St @ 2Nd St to Florence Bus Station via Lewes Transit Center, Wilmington Tc, Wilmington Bus Station, Washington Union Station, and Raleigh Bus Station in around 16h 22m.

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