There are 3 ways to get from Lewes to Frederick by bus (Greyhound), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Lewes Transit Center to Wilmington Tcbus 305
- Take the bus from Wilmington Bus Station to Baltimore Downtown Bus Stationbus
- Take the bus from Baltimore Downtown Bus Terminal, Baltimore, MD to Frederick Bayrunner Officebus
7h 18m$82–120Drive 145.1 mi
cheapest- Drive from Lewes to Frederickcar 145.1 mi
3h 11m$27–39Bus, train
- Take the bus from Lewes Transit Center to Wilmington Tcbus 305
- Take the train from Wilmington to Washington Union Stationtrain
- Take the train from Washington Union Station to FREDERICK MARC wbtrain
7h 43m$34–671
Lewes to Frederick by bus
Questions & Answers
The cheapest way to get from Lewes to Frederick is to drive which costs $26 - $40 and takes 3h 11m.
The fastest way to get from Lewes to Frederick is to drive which takes 3h 11m and costs $26 - $40.
No, there is no direct bus from Lewes to Frederick. However, there are services departing from Market St @ 2Nd St and arriving at Frederick Bayrunner Office via Lewes Transit Center, Wilmington Bus Station and Baltimore Downtown Bus Terminal, Baltimore, MD. The journey, including transfers, takes approximately 7h 18m.
The distance between Lewes and Frederick is 210 miles. The road distance is 145.9 miles.
The best way to get from Lewes to Frederick without a car is to bus which takes 7h 18m and costs $80 - $120.
It takes approximately 7h 18m to get from Lewes to Frederick, including transfers.
Lewes to Frederick bus services, operated by DART First State, depart from Lewes Transit Center station.
Lewes to Frederick bus services, operated by DART First State, arrive at Wilmington Tc station.
Yes, the driving distance between Lewes to Frederick is 146 miles. It takes approximately 3h 11m to drive from Lewes to Frederick.
There are 67+ hotels available in Frederick.
What companies run services between Lewes, DE, USA and Frederick, MD, USA?
You can take a bus from Market St @ 2Nd St to Frederick Bayrunner Office via Lewes Transit Center, Wilmington Tc, Wilmington Bus Station, and Baltimore Downtown Bus Terminal, Baltimore, MD in around 7h 18m.
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Wilmington to Washington Union Station
- Ave. Duration
- 1h 35m
- Frequency
- Hourly
- Estimated price
- $35–75
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Wilmington to Washington Union Station
- Ave. Duration
- 1h 23m
- Frequency
- Every 2 hours
- Estimated price
- $25–650
- Schedules at
- https://www.amtrak.com/acela-train
- Website
- https://www.amtrak.com/home.html
- Business Class
- $25–460
- First Class
- $140–650
- Phone
- 1-866-743-3682
- Website
- mta.maryland.gov
Train from Washington Union Station to FREDERICK MARC wb
- Ave. Duration
- 1h 39m
- Frequency
- Twice daily
- Estimated price
- $2–12
- Website
- https://www.mta.maryland.gov
- Standard Fare
- $2–12
- Phone
- +1 800-652-3278
- Website
- dartfirststate.com
Bus from Lewes Transit Center to Wilmington Tc
- Ave. Duration
- 1h 56m
- Frequency
- Twice daily
- Estimated price
- $5–7
- Website
- https://www.dartfirststate.com/
Bus from Lewes Transit Center to Wilmington Tc
- Ave. Duration
- 1h 56m
- Frequency
- Twice daily
- Estimated price
- $5–7
- Website
- https://www.dartfirststate.com/
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Wilmington Bus Station to Baltimore Downtown Bus Station
- Ave. Duration
- 1h 15m
- Frequency
- 4 times a day
- Estimated price
- $10–21
- Website
- https://www.greyhound.com/
- Website
- greyhound.com
Bus from Wilmington Bus Station to Baltimore Downtown Bus Station
- Ave. Duration
- 1h 15m
- Frequency
- 3 times a day
- Schedules at
- greyhound.com
- Phone
- +1 410-912-6000
- [email protected]
- Website
- bayrunnershuttle.com
Bus from Baltimore Downtown Bus Terminal, Baltimore, MD to Frederick Bayrunner Office
- Ave. Duration
- 50 min
- Frequency
- 4 times a day
- Estimated price
- $65–90
- Schedules at
- bayrunnershuttle.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide


















