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How to get fromLewes to Ithacaby bus, train, car, shuttle, plane, or bus (Greyhound, Flixbus)

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There are 6 ways to get from Lewes to Ithaca by bus, train, car, shuttle, plane, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train

    best
    1. Take the bus from Lewes Transit Center to Wilmington Tcbus bus 305
    2. Take the train from Wilmington to Newark Penn Stationtrain train
    3. Take the bus from Newark Penn Station to Ithacabus bus
    10h 29m
    $66–719

  2. Bus

    cheapest
    1. Take the bus from Lewes Transit Center to Wilmington Tcbus bus 305
    2. Take the bus from Wilmington Bus Station to Newark Penn Stationbus bus
    3. Take the bus from Newark Penn Station to Ithacabus bus
    11h 58m
    $58–104

  3. Drive 331.6 mi

    1. Drive from Lewes to Ithacacar car 331.6 mi
    6h 13m
    $61–88

  4. Shuttle, fly to Rochester, bus

    1. Take a shuttle bus from Lewes Transit Center to Philadelphia Airportshuttle bus
    2. Fly from Philadelphia International Airport (PHL) to Rochester (ROC)plane plane PHL - ROC
    3. Take the bus from Rochester to Ithacabus bus
    8h 46m
    $211–851

  5. Shuttle, bus

    1. Take a shuttle bus from Lewes Transit Center to Philadelphia Airportshuttle bus
    2. Take the bus from Philadelphia 30th St Station to Scrantonbus bus
    3. Take the bus from Scranton, Pa to Ithacabus bus 246
    11h 14m
    $147–215

  6. Shuttle, fly to Syracuse Hancock International Airport, bus

    1. Take a shuttle bus from Lewes Transit Center to Philadelphia Airportshuttle bus
    2. Fly from Philadelphia International Airport (PHL) to Syracuse Hancock International Airport (SYR)plane plane PHL - SYR
    3. Take the bus from Syracuse Bus Station to Ithacabus bus
    8h 57m
    $195–866

Lewes to Ithaca by bus and train

Calendar7Weekly Services
Duration10h 29mAverage Duration
Ticket$66Cheapest Price
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Questions & Answers

Map of how to get from Lewes to Ithaca.ExpandLaunch map view
  • Distance: 411.8 mi
  • Duration: 10h 29m

What companies run services between Lewes, DE, USA and Ithaca, NY, USA?

You can take a bus from Market St @ 2Nd St to Ithaca via Lewes Transit Center, Wilmington Tc, Wilmington Bus Station, and Newark Penn Station in around 11h 58m.

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Train operators
Bus operators

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