There are 4 ways to get from Lewes to Mechanicsburg by bus, train, car, bus (Greyhound, Flixbus), or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, train
best- Take the bus from Lewes Transit Center to Wilmington Tcbus 305
- Take the train from Wilmington to 30th Street Stationtrain
- Take the train from 30th Street Station to Harrisburgtrain
7h 45m$43–631Bus
cheapest- Take the bus from Lewes Transit Center to Wilmington Tcbus 305
- Take the bus from Wilmington Bus Station to Philadelphia Bus Stationbus
- Take the bus from Philadelphia Bus Station to Harrisburg Bus Stationbus
9h 2m$27–50Drive 167.7 mi
- Drive from Lewes to Mechanicsburgcar 167.7 mi
3h 40m$31–45Shuttle, train
- Take a shuttle bus from Lewes Transit Center to Philadelphia Airport
- Take the train from Gray 30th St Station to Downingtowntrain Pao
- Take the train from Downingtown Amtrak to Harrisburgtrain
9h 17m$100–130
Lewes to Mechanicsburg by bus, train, and foot
Questions & Answers
The cheapest way to get from Lewes to Mechanicsburg is to bus which costs $26 - $50 and takes 9h 2m.
The fastest way to get from Lewes to Mechanicsburg is to drive which takes 3h 40m and costs $30 - $45.
No, there is no direct bus from Lewes to Mechanicsburg. However, there are services departing from Market St @ 2Nd St and arriving at E Main St & Arch St WB via Lewes Transit Center, Wilmington Bus Station, Philadelphia Bus Station and Market Square Transfer Center. The journey, including transfers, takes approximately 9h 2m.
The distance between Lewes and Mechanicsburg is 228 miles. The road distance is 168.7 miles.
The best way to get from Lewes to Mechanicsburg without a car is to bus and train which takes 7h 45m and costs $40 - $650.
It takes approximately 7h 45m to get from Lewes to Mechanicsburg, including transfers.
Lewes to Mechanicsburg bus services, operated by DART First State, depart from Lewes Transit Center station.
Lewes to Mechanicsburg bus services, operated by DART First State, arrive at Wilmington Tc station.
Yes, the driving distance between Lewes to Mechanicsburg is 169 miles. It takes approximately 3h 40m to drive from Lewes to Mechanicsburg.
There are 158+ hotels available in Mechanicsburg.
What companies run services between Lewes, DE, USA and Mechanicsburg, Cumberland County, PA, USA?
You can take a bus from Market St @ 2Nd St to E Main St & Arch St WB via Lewes Transit Center, Wilmington Tc, Wilmington Bus Station, Philadelphia Bus Station, Harrisburg Bus Station, and Market Square Transfer Center in around 9h 2m.
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Wilmington to 30th Street Station
- Ave. Duration
- 21 min
- Frequency
- Hourly
- Estimated price
- $7–17
- Website
- Amtrak
Train from 30th Street Station to Harrisburg
- Ave. Duration
- 1h 51m
- Frequency
- Every 2 hours
- Estimated price
- $30–70
- Website
- Amtrak
Train from Downingtown Amtrak to Harrisburg
- Ave. Duration
- 1h 12m
- Frequency
- Every 3 hours
- Estimated price
- $21–50
- Website
- Amtrak
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Wilmington to 30th Street Station
- Ave. Duration
- 25 min
- Frequency
- Every 3 hours
- Estimated price
- $5–550
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $5–440
- First Class
- $100–550
- Phone
- +1 215-580-7800
- Website
- SEPTA
Train from Gray 30th St Station to Downingtown
- Ave. Duration
- 1h 7m
- Frequency
- Every 3 hours
- Estimated price
- $3
- Website
- SEPTA
- Schedules at
- SEPTA: World Cup 2026
- Phone
- +1 800-652-3278
- Website
- DART
Bus from Lewes Transit Center to Wilmington Tc
- Ave. Duration
- 1h 56m
- Frequency
- Twice daily
- Estimated price
- $5–7
- Website
- DART
Bus from Lewes Transit Center to Wilmington Tc
- Ave. Duration
- 1h 56m
- Frequency
- Twice daily
- Estimated price
- $5–7
- Website
- DART
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Wilmington Bus Station to Philadelphia Bus Station
- Ave. Duration
- 45 min
- Frequency
- 4 times a day
- Estimated price
- $4–9
- Website
- Greyhound
Bus from Philadelphia Bus Station to Harrisburg Bus Station
- Ave. Duration
- 2h
- Frequency
- 3 times a day
- Estimated price
- $15–30
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Philadelphia Bus Station to Harrisburg Bus Station
- Ave. Duration
- 2h 50m
- Frequency
- 5 times a week
- Estimated price
- $16–27
- Schedules at
- Flixbus USA
- Phone
- +1 302-470-6784
- [email protected]
- Website
- Lewes Bus
Shuttle from Lewes Transit Center to Philadelphia Airport
- Ave. Duration
- 2h
- Frequency
- Twice daily
- Estimated price
- $70
- Schedules at
- Lewes Bus
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