Rome2Rio

How to get fromLewes to Pittsburghby bus (Greyhound, Flixbus), bus, train, car, shuttle, or plane

Find Transport to Pittsburgh

See all options

There are 7 ways to get from Lewes to Pittsburgh by bus (Greyhound, Flixbus), bus, train, car, shuttle, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Lewes Transit Center to Wilmington Tcbus bus 305
    2. Take the bus from Wilmington Bus Station to Philadelphia Bus Stationbus bus
    3. Take the bus from Philadelphia Bus Station to Pittsburgh Intermodal Stationbus bus
    11h 53m
    $56–108

  2. Bus, train

    1. Take the bus from Lewes Transit Center to Wilmington Tcbus bus 305
    2. Take the train from Wilmington to 30th Street Stationtrain train
    3. Take the train from 30th Street Station to Pittsburgh Amtrak Stationtrain train
    12h 14m
    $122–789

  3. Drive 332.3 mi

    1. Drive from Lewes to Pittsburghcar car 332.3 mi
    6h 53m
    $61–88

  4. Shuttle to Philadelphia International Airport, fly to Pittsburgh International Airport

    1. Take a shuttle bus from Lewes Transit Center to Philadelphia Airportshuttle bus
    2. Fly from Philadelphia International Airport (PHL) to Pittsburgh International Airport (PIT)plane plane PHL - PIT
    7h 8m
    $192–922

  5. Bus, train to Baltimore-Washington International Airport, fly to Pittsburgh International Airport

    1. Take the bus from Lewes Transit Center to Wilmington Tcbus bus
    2. Take the train from Wilmington to BWI Thurgood Marshalltrain train
    3. Fly from Baltimore-Washington International Airport (BWI) to Pittsburgh International Airport (PIT)plane plane BWI - PIT
    8h 25m
    $875–1,909

  6. Shuttle to Philadelphia International Airport, fly to Penn State University Park Airport, bus

    1. Take a shuttle bus from Lewes Transit Center to Philadelphia Airportshuttle bus
    2. Fly from Philadelphia International Airport (PHL) to Penn State University Park Airport (SCE)plane plane PHL - SCE
    3. Take the bus from State College Regional Airport to Pittsburgh Intermodal Stationbus bus
    9h 27m
    $144–502

  7. Bus, train to Ronald Reagan Washington National Airport, fly to Pittsburgh International Airport

    1. Take the bus from Lewes Transit Center to Wilmington Tcbus bus
    2. Take the train from Wilmington to Washington Union Stationtrain train
    3. Fly from Ronald Reagan Washington National Airport (DCA) to Pittsburgh International Airport (PIT)plane plane DCA - PIT
    9h 14m
    $1,036–2,366

Lewes to Pittsburgh by bus

Calendar12Weekly Buses
Duration11h 53mAverage Duration
Ticket$56Cheapest Price
See schedules

Questions & Answers

Map of how to get from Lewes to Pittsburgh.ExpandLaunch map view
  • Distance: 421.2 mi
  • Duration: 11h 53m

What companies run services between Lewes, DE, USA and Pittsburgh, PA, USA?

You can take a bus from Market St @ 2Nd St to Pittsburgh Intermodal Station via Lewes Transit Center, Wilmington Tc, Wilmington Bus Station, and Philadelphia Bus Station in around 11h 53m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound