There are 4 ways to get from Lewis Center to Louisville by bus (Greyhound, Amtrak), car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Columbus to Indianapolis Union Stationbus Greyhound US0421
- Take the bus from Indianapolis Union Station to Louisville, KYbus Chicago
7h 30m$99–151Drive 224.2 mi
cheapest- Drive from Lewis Center to Louisvillecar 224.2 mi
3h 51m$41–60Fly to Louisville International Airport
- Fly from John Glenn Columbus International Airport (CMH) to Louisville International Airport (SDF)plane CMH - SDF
5h 12m$189–960Fly to Blue Grass Airport, drive
- Fly from John Glenn Columbus International Airport (CMH) to Blue Grass Airport (LEX)plane CMH - LEX
- Drive from Lexington-Airport-LEX to Louisvillecar
5h 5m$136–556
John Glenn Columbus International Airport (CMH) to Louisville International Airport (SDF) flights
Comparing Your Travel Options
The cheapest way to get from Lewis Center to Louisville is to drive which costs $40 - $60 and takes 3h 51m.
The fastest way to get from Lewis Center to Louisville is to drive which takes 3h 51m and costs $40 - $60.
No, there is no direct bus from Lewis Center to Louisville. However, there are services departing from Columbus and arriving at Louisville, KY via Indianapolis Union Station. The journey, including transfers, takes approximately 7h 30m.
The distance between Lewis Center and Louisville is 320 miles. The road distance is 225.5 miles.
The best way to get from Lewis Center to Louisville without a car is to bus which takes 7h 30m and costs $95 - $160.
It takes approximately 7h 30m to get from Lewis Center to Louisville, including transfers.
Lewis Center to Louisville bus services, operated by Greyhound USA, depart from Columbus station.
The best way to get from Lewis Center to Louisville is to bus which takes 7h 30m and costs $95 - $160. Alternatively, you can fly, which costs $180 - $1,000 and takes 5h 12m.
Lewis Center to Louisville bus services, operated by Greyhound USA, arrive at Indianapolis Union Station.
Yes, the driving distance between Lewis Center to Louisville is 226 miles. It takes approximately 3h 51m to drive from Lewis Center to Louisville.
What companies run services between Lewis Center, OH, USA and Louisville, KY, USA?
You can take a vehicle from Lewis Center to Louisville, KY via Columbus and Indianapolis Union Station in around 7h 30m. Alternatively, Southwest Airlines, Delta, and two other airlines fly from John Glenn Columbus International Airport (CMH) to Louisville International Airport (SDF) hourly.
- Website
- aa.com
Flights from John Glenn Columbus International Airport to Louisville International Airport via Charlotte
- Ave. Duration
- 4h 26m
- When
- Every day
- Estimated price
- $170–1,000
Flights from John Glenn Columbus International Airport to Blue Grass Airport via Charlotte
- Ave. Duration
- 4h 30m
- When
- Thursday to Saturday
- Estimated price
- $90–550
Flights from John Glenn Columbus International Airport to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- $90–550
Flights from John Glenn Columbus International Airport to Blue Grass Airport via Philadelphia
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- $110–600
- Website
- delta.com
Flights from John Glenn Columbus International Airport to Louisville International Airport via Detroit
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- $140–900
Flights from John Glenn Columbus International Airport to Louisville International Airport via Atlanta
- Ave. Duration
- 4h 46m
- When
- Every day
- Estimated price
- $190–1,000
Flights from John Glenn Columbus International Airport to Blue Grass Airport via Detroit
- Ave. Duration
- 3h 33m
- When
- Thursday and Sunday
- Estimated price
- $75–480
Flights from John Glenn Columbus International Airport to Blue Grass Airport via Atlanta
- Ave. Duration
- 4h 9m
- When
- Every day
- Estimated price
- $100–550
Flights from John Glenn Columbus International Airport to Blue Grass Airport via New York La Guardia
- Ave. Duration
- 5h 4m
- When
- Thursday and Sunday
- Estimated price
- $130–650
- Website
- southwest.com
Flights from John Glenn Columbus International Airport to Louisville International Airport via Nashville
- Ave. Duration
- 4h 41m
- When
- Saturday, Monday, Thursday, and Friday
- Estimated price
- $140–900
Flights from John Glenn Columbus International Airport to Louisville International Airport via Baltimore
- Ave. Duration
- 4h 26m
- When
- Every day
- Estimated price
- $190–1,100
Flights from John Glenn Columbus International Airport to Louisville International Airport via Chicago Midway
- Ave. Duration
- 5h 10m
- When
- Monday
- Estimated price
- $150–900
- Website
- united.com
Flights from John Glenn Columbus International Airport to Louisville International Airport via Washington Dulles
- Ave. Duration
- 4h 21m
- When
- Every day
- Estimated price
- $180–1,000
Flights from John Glenn Columbus International Airport to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 4h 32m
- When
- Every day
- Estimated price
- $90–550
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Columbus to Indianapolis Union Station
- Ave. Duration
- 4h 10m
- Frequency
- 3 times a day
- Estimated price
- $30–50
- Website
- Greyhound
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Indianapolis Union Station to Louisville, KY
- Ave. Duration
- 1h 55m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Amtrak
- Adult
- $22–45
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