Rome2Rio

How to get fromLewiston to Chicagoby bus, plane, train (Amtrak), bus (Greyhound), car, train, or bus (Flixbus)

Find Transport to Chicago

See all options

There are 8 ways to get from Lewiston to Chicago by bus, plane, train (Amtrak), bus (Greyhound), car, train, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Buffalo Niagara International Airport, fly to Chicago Midway International Airport

    best
    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Chicago Midway International Airport (MDW)plane plane BUF - MDW
    5h 32m
    $167–384

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Buffalo to Cleveland Bus Stationbus bus Greyhound US0171 / ...
    2. Take the bus from Cleveland Bus Station to Chicago Bus Stationbus bus Greyhound US0164
    14h 34m
    $84–164

  3. Train

    1. Take the train from Niagara Falls Amtrak Station to Buffalo Depew Stationtrain train Maple Leaf / ...
    2. Take the train from Buffalo Depew Station to Chicago Union Stationtrain train Lake Shore Limited
    12h 27m
    $203–528

  4. Drive 521.4 mi

    1. Drive from Lewiston to Chicagocar car 521.4 mi
    8h 45m
    $96–138

  5. Bus to Buffalo Niagara International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Chicago O'Hare International Airport (ORD)plane plane BUF - ORD
    5h 55m
    $177–314

  6. Train to Rochester, fly to Chicago Midway International Airport

    1. Take the train from Niagara Falls Amtrak Station to Rochestertrain train
    2. Fly from Rochester (ROC) to Chicago Midway International Airport (MDW)plane plane ROC - MDW
    7h 26m
    $128–650

  7. Train to Toronto Island Airport, fly to Chicago O'Hare International Airport

    1. Take the train from Canadian Border to Torontotrain train
    2. Fly from Toronto Island Airport (YTZ) to Chicago O'Hare International Airport (ORD)plane plane YTZ - ORD
    8h 45m
    $208–1,360

  8. Bus via Detroit (Flixbus)

    1. Take the bus from Niagara Falls USA to Toronto Pearson Airportbus bus
    2. Take the bus from Toronto Pearson Airport to Detroit Bus Stationbus bus
    3. Take the bus from Detroit Bus Station to Chicagobus bus
    20h 13m
    $105–188

Lewiston to Chicago by bus (Greyhound)

Calendar14Weekly Buses
Duration14h 34mAverage Duration
Ticket$84Cheapest Price
See schedules

Questions & Answers

Map of how to get from Lewiston to Chicago.ExpandLaunch map view
  • Distance: 521.9 mi
  • Duration: 5h 32m

What companies run services between Lewiston, NY, USA and Chicago, IL, USA?

You can take a vehicle from Lewiston to Chicago Union Station via Niagara Falls Amtrak Station and Buffalo Depew Station in around 12h 27m. Alternatively, you can take a bus from Academy Park to Chicago Bus Station via Fashion Outlet Boulevard & NFTC, Ellicott Street & MTC Static, Buffalo, and Cleveland Bus Station in around 14h 34m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

More Questions & Answers