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How to get fromLexington to Indianapolisby plane, bus, train, train (Amtrak), car, or bus (Greyhound)

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There are 8 ways to get from Lexington to Indianapolis by plane, bus, train, train (Amtrak), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Piedmont Triad International Airport

    best
    1. Fly from Piedmont Triad International Airport (GSO) to Indianapolis (IND)plane plane GSO - IND
    7h 23m
    $146–731

  2. Bus

    cheapest
    1. Take the bus from Lexington Davidson Co Trans Term to Winston Salem(Trans Center)bus bus
    2. Take the bus from Winston Salem(Trans Center) to Columbus - Mound Stbus bus
    3. Take the bus from Columbus to Indianapolis Union Stationbus bus
    16h 40m
    $68–153

  3. Bus, train

    1. Take the bus from Lexington Davidson Co Trans Term to Winston Salem(Trans Center)bus bus
    2. Take the bus from Winston Salem(Trans Center) to Ashlandbus bus
    3. Take the train from Ashland Amtrak Station to Indianapolistrain train
    16h 26m
    $118–258

  4. Train (Amtrak)

    1. Take the train from High Point to Charlottesvilletrain train Crescent
    2. Take the train from Charlottesville to Indianapolistrain train Cardinal
    21h 46m
    $248–534

  5. Drive 532 mi

    1. Drive from Lexington to Indianapoliscar car 532 mi
    9h 30m
    $98–141

  6. Bus, train to Charlotte Douglas International Airport, fly

    1. Take the bus from Lexington Davidson Co Trans Term to High Point Transportation Terminalbus bus
    2. Take the train from High Point to Charlotte Amtrak Stationtrain train
    3. Fly from Charlotte Douglas International Airport (CLT) to Indianapolis (IND)plane plane CLT - IND
    7h 41m
    $135–667

  7. Train to Raleigh-Durham International Airport, fly

    1. Take the train from High Point to Durham Amtrak Stationtrain train
    2. Fly from Raleigh-Durham International Airport (RDU) to Indianapolis (IND)plane plane RDU - IND
    8h 20m
    $126–612

  8. Train to Concord, fly

    1. Take the train from High Point to Kannapolistrain train
    2. Fly from Concord (USA) to Indianapolis (IND)plane plane USA - IND
    6h 19m
    $221–596

Lexington to Indianapolis by bus and train

Calendar3Weekly Services
Duration16h 26mAverage Duration
Ticket$118Cheapest Price
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Questions & Answers

Map of how to get from Lexington to Indianapolis.ExpandLaunch map view
  • Distance: 474.2 mi
  • Duration: 7h 23m

What companies run services between Lexington, NC, USA and Indianapolis, IN, USA?

Delta, American Airlines, and United Airlines fly from Piedmont Triad International Airport (GSO) to Indianapolis (IND) hourly. Alternatively, you can take a bus from Lexington Davidson Co Trans Term to Indianapolis via High Point Transportation Terminal, High Point, and Charlottesville in around 21h 46m.

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