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How to get fromLexington to Buffaloby plane, bus (Greyhound), bus, train, car, or bus (Flixbus)

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There are 6 ways to get from Lexington to Buffalo by plane, bus (Greyhound), bus, train, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Columbia (CAE) to Buffalo Niagara International Airport (BUF)plane plane CAE - BUF
    5h 2m
    $299–1,563

  2. Drive 754.8 mi

    cheapest
    1. Drive from Lexington to Buffalocar car 754.8 mi
    13h
    $138–199

  3. Bus via Columbus

    1. Take the bus from Columbia, SC to Camdenbus bus
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte Bus Station to Columbusbus bus
    4. Take the bus from Columbus - Mound St to Buffalo, NYbus bus
    22h 57m
    $155–286

  4. Bus, train via Charlotte

    1. Take the bus from Columbia, SC to Camdenbus bus
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Take the train from Charlotte Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    4. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train
    27h 27m
    $416–810

  5. Bus

    1. Take the bus from Columbia, SC to New York, NYbus bus Augusta
    2. Take the bus from New York Midtown to Buffalobus bus FlixBus 2686 / ...
    24h 23m
    $203–315

  6. Bus, train

    1. Take the bus from Columbia, SC to New York, NYbus bus Augusta
    2. Take the train from New York Penn Station to Buffalotrain train VIA Rail
    24h 34m
    $243–475

Columbia (CAE) to Buffalo Niagara International Airport (BUF) flights

Calendar131Weekly Planes
Duration5h 14mAverage Duration
Ticket$277Cheapest Price
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Questions & Answers

Map of how to get from Lexington to Buffalo.ExpandLaunch map view
  • Distance: 656.9 mi
  • Duration: 5h 2m

What companies run services between Lexington, SC, USA and Buffalo, NY, USA?

United Airlines, American Airlines, and Delta fly from Columbia (CAE) to Buffalo Niagara International Airport (BUF) hourly. Alternatively, you can take a vehicle from Lexington to Buffalo, NY via Columbia, SC, Camden, Charlotte Bus Station, and Columbus - Mound St in around 22h 57m.

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