There are 6 ways to get from Lexington to Buffalo by plane, bus (Greyhound), bus, train, car, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Columbia (CAE) to Buffalo Niagara International Airport (BUF)plane CAE - BUF
5h 28m$128–612Bus via Columbus
- Take the bus from Columbia, SC to Camdenbus
- Take the bus from Camden to Charlotte Bus Stationbus
- Take the bus from Charlotte Bus Station to Columbusbus
- Take the bus from Columbus to Buffalobus
22h 57m$156–283Bus, train via Charlotte
- Take the bus from Columbia, SC to Camdenbus
- Take the bus from Camden to Charlotte Bus Stationbus
- Take the train from Charlotte Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain
27h 27m$657–1,047Drive 754.8 mi
- Drive from Lexington to Buffalocar 754.8 mi
13h$138–199Bus, train
- Take the bus from Columbia, SC to New York, NYbus Augusta
- Take the train from New York Penn Station to Buffalotrain VIA Rail
24h 34m$243–465Bus
- Take the bus from Columbia, SC to New York, NYbus Augusta
- Take the bus from New York Midtown to Buffalobus FlixBus 2686 / ...
24h 51m$203–295
Columbia (CAE) to Buffalo Niagara International Airport (BUF) flights
Comparing Your Travel Options
The cheapest way to get from Lexington to Buffalo is to drive which costs $130 - $200 and takes 13h.
The fastest way to get from Lexington to Buffalo is to fly which takes 5h 28m and costs $120 - $650.
No, there is no direct bus from Lexington to Buffalo. However, there are services departing from Columbia, SC and arriving at Buffalo via Camden, Charlotte Bus Station and Columbus. The journey, including transfers, takes approximately 22h 57m.
The distance between Lexington and Buffalo is 656 miles. The road distance is 759.2 miles.
The best way to get from Lexington to Buffalo without a car is to bus via Columbus which takes 22h 57m and costs $150 - $290.
It takes approximately 5h 28m to get from Lexington to Buffalo, including transfers.
Lexington to Buffalo bus services, operated by Wanda Coach, depart from Columbia, SC station.
The best way to get from Lexington to Buffalo is to fly which takes 5h 28m and costs $120 - $650. Alternatively, you can bus via Columbus, which costs $150 - $290 and takes 22h 57m.
Lexington to Buffalo bus services, operated by Wanda Coach, arrive at Camden station.
Yes, the driving distance between Lexington to Buffalo is 759 miles. It takes approximately 13h to drive from Lexington to Buffalo.
What companies run services between Lexington, SC, USA and Buffalo, NY, USA?
United Airlines, American Airlines, and Delta fly from Columbia (CAE) to Buffalo Niagara International Airport (BUF) hourly. Alternatively, you can take a vehicle from Lexington to Buffalo via Columbia, SC, Camden, Charlotte Bus Station, and Columbus in around 22h 57m.
- Website
- aa.com
Flights from Columbia to Buffalo Niagara International Airport via Charlotte
- Ave. Duration
- 4h 54m
- When
- Every day
- Estimated price
- $95–550
Flights from Columbia to Buffalo Niagara International Airport via Reagan Washington
- Ave. Duration
- 6h 3m
- When
- Every day
- Estimated price
- $100–600
Flights from Columbia to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 5h 32m
- When
- Every day
- Estimated price
- $120–650
Flights from Columbia to Buffalo Niagara International Airport via Philadelphia
- Ave. Duration
- 5h 40m
- When
- Every day
- Estimated price
- $110–600
Flights from Columbia to Buffalo Niagara International Airport via Chicago O'Hare
- Ave. Duration
- 7h 6m
- When
- Every day
- Estimated price
- $140–700
- Website
- delta.com
Flights from Columbia to Buffalo Niagara International Airport via Atlanta
- Ave. Duration
- 4h 59m
- When
- Every day
- Estimated price
- $120–650
Flights from Columbia to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 6h 34m
- When
- Every day
- Estimated price
- $120–650
- Website
- united.com
Flights from Columbia to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 4h 2m
- When
- Every day
- Estimated price
- $100–600
Flights from Columbia to Buffalo Niagara International Airport via Chicago O'Hare
- Ave. Duration
- 6h 38m
- When
- Every day
- Estimated price
- $140–700
Flights from Columbia to Buffalo Niagara International Airport via Newark
- Ave. Duration
- 7h 10m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–650
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Charlotte Amtrak Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 13h 11m
- Frequency
- Twice daily
- Estimated price
- $330–550
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Buffalo
- Ave. Duration
- 8h 35m
- Frequency
- 3 times a day
- Estimated price
- $240–380
- Website
- Amtrak
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from New York Penn Station to Buffalo
- Ave. Duration
- 8h 24m
- Frequency
- Once daily
- Estimated price
- $110–280
- Website
- VIA Rail
- Escape
- $110–260
- Business
- $150–270
- Business Plus
- $160–280
- Economy
- $130–260
- Economy Plus
- $140–270
- Phone
- +1 646-630-7186
- [email protected]
- Website
- Wanda Coach
Bus from Columbia, SC to Camden
- Ave. Duration
- 43 min
- Frequency
- Once daily
- Estimated price
- $28–40
- Website
- Wanda Coach
- Book at
- GotoBus.com
- Adult One Way
- $28–40
Bus from Columbia, SC to Camden
- Ave. Duration
- 43 min
- Frequency
- Once daily
- Estimated price
- $28–40
- Website
- Wanda Coach
- Book at
- GotoBus.com
- Adult One Way
- $28–40
Bus from Columbia, SC to New York, NY
- Ave. Duration
- 14h 26m
- Frequency
- Once daily
- Estimated price
- $95–140
- Website
- Wanda Coach
- Book at
- GotoBus.com
- Adult One Way
- $95–140
Bus from Columbia, SC to New York, NY
- Ave. Duration
- 14h 26m
- Frequency
- Once daily
- Estimated price
- $95–140
- Website
- Wanda Coach
- Book at
- GotoBus.com
- Adult One Way
- $95–140
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Camden to Charlotte Bus Station
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $13–21
- Website
- Greyhound
Bus from Charlotte Bus Station to Columbus
- Ave. Duration
- 10h 5m
- Frequency
- Once daily
- Estimated price
- $80–130
- Website
- Greyhound
Bus from Camden to Charlotte Bus Station
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $13–21
- Website
- Greyhound
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Charlotte Bus Station to Columbus
- Ave. Duration
- 10h 45m
- Frequency
- Once daily
- Estimated price
- $45–100
- Website
- Barons Bus
Bus from Columbus to Buffalo
- Ave. Duration
- 7h 15m
- Frequency
- Once daily
- Estimated price
- $35–80
- Website
- Barons Bus
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from New York Midtown to Buffalo
- Ave. Duration
- 8h 35m
- Frequency
- Every 4 hours
- Estimated price
- $70–110
- Schedules at
- Flixbus USA
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