There are 3 ways to get from Lexington to Knoxville by plane, bus, taxi, shuttle, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Columbia (CAE) to Mcghee Tyson Airport (TYS)plane CAE - TYS
3h 32m$263–1,404Drive 259.5 mi
cheapest- Drive from Lexington to Knoxvillecar 259.5 mi
4h 35m$48–69Bus, taxi, shuttle, drive
- Take the bus from Columbia, SC to Camdenbus
- Take the bus from Camden to Charlotte Bus Stationbus
- Take the bus from Charlotte Airport to ASU Peacock Hall Boonebus
- Take the taxi from ASU Peacock Hall Boone to Black Bear Resorttaxi
- Take a shuttle bus from Black Bear Resort to Hot Springs
- Drive from Hot Springs to Chilhowee at Holstoncar
12h 41m$464–562
Columbia (CAE) to Mcghee Tyson Airport (TYS) flights
Questions & Answers
The cheapest way to get from Lexington to Knoxville is to drive which costs $45 - $70 and takes 4h 35m.
The fastest way to get from Lexington to Knoxville is to fly which takes 3h 32m and costs $260 - $1,400.
The distance between Lexington and Knoxville is 230 miles. The road distance is 261 miles.
It takes approximately 3h 32m to get from Lexington to Knoxville, including transfers.
Yes, the driving distance between Lexington to Knoxville is 261 miles. It takes approximately 4h 35m to drive from Lexington to Knoxville.
There are 279+ hotels available in Knoxville.
What companies run services between Lexington, SC, USA and Knoxville, TN, USA?
Delta, American Airlines, and United Airlines fly from Columbia (CAE) to Mcghee Tyson Airport (TYS) hourly.
- Website
- aa.com
Flights from Columbia to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- $180–1,300
Flights from Columbia to Mcghee Tyson Airport via Reagan Washington
- Ave. Duration
- 4h 44m
- When
- Sunday, Monday, Tuesday, Wednesday, Thursday, and Friday
- Estimated price
- $350–1,700
Flights from Columbia to Mcghee Tyson Airport via Chicago O'Hare
- Ave. Duration
- 5h 59m
- When
- Every day
- Estimated price
- $430–2,000
Flights from Columbia to Mcghee Tyson Airport via Philadelphia
- Ave. Duration
- 5h 20m
- When
- Every day
- Estimated price
- $410–1,900
- Website
- delta.com
Flights from Columbia to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 3h 51m
- When
- Every day
- Estimated price
- $210–1,300
- Website
- united.com
Flights from Columbia to Mcghee Tyson Airport via Washington Dulles
- Ave. Duration
- 4h 51m
- When
- Every day
- Estimated price
- $340–1,700
Flights from Columbia to Mcghee Tyson Airport via Chicago O'Hare
- Ave. Duration
- 6h 43m
- When
- Every day
- Estimated price
- $430–2,000
- Phone
- +1 646-630-7186
- [email protected]
- Website
- Wanda Coach
Bus from Columbia, SC to Camden
- Ave. Duration
- 43 min
- Frequency
- Once daily
- Estimated price
- $28–40
- Website
- Wanda Coach
- Book at
- GotoBus.com
- Adult One Way
- $28–40
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Camden to Charlotte Bus Station
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $11–23
- Website
- Greyhound
- Phone
- +1 828-327-2340
- [email protected]
- Website
- Hickory Hop
Bus from Charlotte Airport to ASU Peacock Hall Boone
- Ave. Duration
- 2h 30m
- Frequency
- 5 times a day
- Estimated price
- $90–110
- Schedules at
- Hickory Hop
- Phone
- +1-423-725-5988
- Website
- Black Bear Resort Shuttle
Shuttle from Black Bear Resort to Hot Springs
- Ave. Duration
- 1h 30m
- Frequency
- On demand
- Estimated price
- $136
- Website
- Black Bear Resort Shuttle
- Ave. Duration
- 1h 10m
- Estimated price
- $120–150
High Country Taxi
- Phone
- +1 828-414-1492
- Website
- highcountrytaxi.com
Tipsy Taxi
- Phone
- +1 828-719-8477
- Website
- facebook.com
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