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How to get fromLexington to Pittsburghby plane, bus (Greyhound), bus, train, car, or bus (Greyhound, Flixbus)

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There are 8 ways to get from Lexington to Pittsburgh by plane, bus (Greyhound), bus, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Columbia

    best
    1. Fly from Columbia (CAE) to Pittsburgh International Airport (PIT)plane plane CAE - PIT
    5h 18m
    $98–454

  2. Drive to Greenville–Spartanburg International Airport, fly

    cheapest
    1. Drive from Lexington to Greenville–Spartanburg International Airport (GSP)car car
    2. Fly from Greenville–Spartanburg International Airport (GSP) to Pittsburgh International Airport (PIT)plane plane GSP - PIT
    4h 50m
    $93–476

  3. Bus

    1. Take the bus from Columbia, SC to Camdenbus bus
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte to Winston Salembus bus
    4. Take the bus from Winston Salem to Charlestonbus bus
    5. Take the bus from Charleston to Morgantown Mt Linebus bus
    6. Take the bus from Westover Terminal to Pittsburgh Greyhoundbus bus
    18h 52m
    $123–288

  4. Bus, train

    1. Take the bus from Columbia, SC to Raleigh, NCbus bus Augusta
    2. Take the train from Cary to Pittsburgh Amtrak Stationtrain train Floridian
    20h 36m
    $416–666

  5. Drive  544.4 mi

    1. Drive from Lexington to Pittsburghcar car 544.4 mi
    9h 24m
    $100–144

  6. Drive to Charleston International Airport, fly

    1. Drive from Lexington to Charleston-Airport-CHScar car
    2. Fly from Charleston International Airport (CHS) to Pittsburgh International Airport (PIT)plane plane CHS - PIT
    5h 10m
    $105–529

  7. Bus via Baltimore

    1. Take the bus from Columbia, SC to Baltimore, MDbus bus Augusta
    2. Take the bus from Baltimore Downtown Bus Station to Pittsburgh Intermodal Stationbus bus Greyhound US0164 / ...
    19h 51m
    $149–231

  8. Bus, train via Charlotte

    1. Take the bus from Columbia, SC to Camdenbus bus
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Take the train from Charlotte Amtrak Station to Raleigh Union Stationtrain train
    4. Take the train from Raleigh Union Station to Pittsburgh Amtrak Stationtrain train
    23h 20m
    $503–767

Columbia (CAE) to Pittsburgh International Airport (PIT) flights

Calendar129Weekly Planes
Duration4h 18mAverage Duration
Ticket$69Cheapest Price
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Comparing Your Travel Options

Map of how to get from Lexington to Pittsburgh.ExpandLaunch map view
  • Distance: 489 mi
  • Duration: 5h 18m

What companies run services between Lexington, SC, USA and Pittsburgh, PA, USA?

American Airlines, United Airlines, and Delta fly from Columbia (CAE) to Pittsburgh International Airport (PIT) hourly. Alternatively, you can take a vehicle from Lexington to Pittsburgh Greyhound via Columbia, SC, Camden, Charlotte, Winston Salem, Charleston, Morgantown Mt Line, and Westover Terminal in around 18h 52m.

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