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How to get fromLexington to Pittsburghby plane, bus (Greyhound), bus, train, or car

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There are 7 ways to get from Lexington to Pittsburgh by plane, bus (Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Columbia

    best
    1. Fly from Columbia (CAE) to Pittsburgh International Airport (PIT)plane plane CAE - PIT
    5h 17m
    $103–504

  2. Drive to Greenville–Spartanburg International Airport, fly

    cheapest
    1. Drive from Lexington to Greenville–Spartanburg International Airport (GSP)car car
    2. Fly from Greenville–Spartanburg International Airport (GSP) to Pittsburgh International Airport (PIT)plane plane GSP - PIT
    4h 49m
    $92–484

  3. Bus

    1. Take the bus from Columbia, SC to Camdenbus bus
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte Bus Station to Charleston Bus Stationbus bus
    4. Take the bus from Charleston to Cambridgebus bus
    5. Take the bus from Cambridge, OH to Pittsburgh Intermodal Stationbus bus
    17h 2m
    $160–268

  4. Bus, train

    1. Take the bus from Columbia, SC to Raleigh, NCbus bus Augusta
    2. Take the train from Cary to Pittsburgh Amtrak Stationtrain train Floridian
    20h 36m
    $416–666

  5. Drive  542.8 mi

    1. Drive from Lexington to Pittsburghcar car 542.8 mi
    9h 28m
    $93–134

  6. Drive to Charleston International Airport, fly

    1. Drive from Lexington to Charleston-Airport-CHScar car
    2. Fly from Charleston International Airport (CHS) to Pittsburgh International Airport (PIT)plane plane CHS - PIT
    5h 9m
    $114–578

  7. Bus, train via Charlotte

    1. Take the bus from Columbia, SC to Camdenbus bus
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Take the train from Charlotte Amtrak Station to Raleigh Union Stationtrain train
    4. Take the train from Raleigh Union Station to Pittsburgh Amtrak Stationtrain train
    23h 20m
    $503–768

Columbia (CAE) to Pittsburgh International Airport (PIT) flights

Calendar122Weekly Planes
Duration4h 39mAverage Duration
Ticket$78Cheapest Price
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Comparing Your Travel Options

Map of how to get from Lexington to Pittsburgh.ExpandLaunch map view
  • Distance: 489 mi
  • Duration: 5h 17m

What companies run services between Lexington, SC, USA and Pittsburgh, PA, USA?

United Airlines, American Airlines, and Delta fly from Columbia (CAE) to Pittsburgh International Airport (PIT) hourly. Alternatively, you can take a vehicle from Lexington to Pittsburgh Intermodal Station via Columbia, SC, Camden, Charlotte Bus Station, Charleston Bus Station, Charleston, and Cambridge, OH in around 17h 2m.

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