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How to get fromLexington to Buffaloby car, plane, bus, or train

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There are 9 ways to get from Lexington to Buffalo by car, plane, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Covington, fly to Buffalo Niagara International Airport

    best
    1. Drive from Lexington to Covington (CVG)car car
    2. Fly from Covington (CVG) to Buffalo Niagara International Airport (BUF)plane plane CVG - BUF
    5h 50m
    $167–264

  2. Drive, bus via Akron

    cheapest
    1. Drive from Lexington to Middletown Station @ Targetcar car
    2. Take the bus from Louisville to Akronbus bus
    3. Take the bus from Akron to Buffalobus bus
    15h 27m
    $65–168

  3. Drive, bus

    1. Drive from Lexington to Middletown Station @ Targetcar car
    2. Take the bus from Louisville, KY Bus Station to Cleveland Ohio Greyhound Stationbus bus
    3. Take the bus from Cleveland, OH to Buffalo, NYbus bus
    14h 56m
    $67–163

  4. Drive  518.7 mi

    1. Drive from Lexington to Buffalocar car 518.7 mi
    8h 55m
    $95–137

  5. Drive to Louisville International Airport, fly to Buffalo Niagara International Airport

    1. Drive from Lexington to Louisville-Airport-SDFcar car
    2. Fly from Louisville International Airport (SDF) to Buffalo Niagara International Airport (BUF)plane plane SDF - BUF
    5h 59m
    $126–723

  6. Fly Blue Grass Airport to Buffalo Niagara International Airport

    1. Fly from Blue Grass Airport (LEX) to Buffalo Niagara International Airport (BUF)plane plane LEX - BUF
    8h
    $94–554

  7. Drive to Covington, fly to Toronto Pearson International Airport, bus

    1. Drive from Lexington to Covington (CVG)car car
    2. Fly from Covington (CVG) to Toronto Pearson International Airport (YYZ)plane plane CVG - YYZ
    3. Take the bus from Toronto Pearson Airport to Buffalobus bus
    7h 9m
    $629–1,045

  8. Drive, bus #2

    1. Drive from Lexington to Middletown Station @ Targetcar car
    2. Take the bus from Louisville Bus Station to Cincinnati Bus Stationbus bus
    3. Take the bus from Cincinnati, OH to Buffalo, NYbus bus
    15h 57m
    $69–163

  9. Drive, bus, train

    1. Drive from Lexington to Middletown Station @ Targetcar car
    2. Take the bus from Louisville Bus Station to Toledo Bus Stopbus bus
    3. Take the train from Toledo to Buffalo Depew Stationtrain train
    18h 7m
    $131–408

Covington (CVG) to Buffalo Niagara International Airport (BUF) flights

Calendar113Weekly Planes
Duration5h 5mAverage Duration
Ticket$118Cheapest Price
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Comparing Your Travel Options

Map of how to get from Lexington to Buffalo.ExpandLaunch map view
  • Distance: 503.3 mi
  • Duration: 5h 50m

What companies run services between Lexington, KY, USA and Buffalo, NY, USA?

United Airlines, Delta, and American Airlines fly from Blue Grass Airport (LEX) to Buffalo Niagara International Airport (BUF) hourly.

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