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How to get fromLexington to Cape Girardeauby bus, train, taxi, car, plane, or bus (Greyhound)

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There are 5 ways to get from Lexington to Cape Girardeau by bus, train, taxi, car, plane, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train, taxi

    best
    1. Take the bus from Lexington Bus Stop to Cincinnati Bus Stationbus bus
    2. Take the bus from Cincinnati Bus Station to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Champaign Intermodal Trans Ctrbus bus
    4. Take the train from Champaign-Urbana to Carbondaletrain train
    5. Take the taxi from Carbondale to Cape Girardeautaxi taxi
    12h 51m

  2. Drive 325.1 mi

    cheapest
    1. Drive from Lexington to Cape Girardeaucar car 325.1 mi
    5h 48m
    $60–86

  3. Fly to Williamson County Regional Airport, taxi

    1. Fly from Blue Grass Airport (LEX) to Williamson County Regional Airport (MWA)plane plane LEX - MWA
    2. Take the taxi from Williamson County Regional Airport (MWA) to Cape Girardeautaxi taxi
    8h 35m
    $232–762

  4. Bus

    1. Take the bus from Lexington Bus Stop to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    14h 38m

  5. Fly to Barkley Regional Airport, taxi

    1. Fly from Blue Grass Airport (LEX) to Barkley Regional Airport (PAH)plane plane LEX - PAH
    2. Take the taxi from Barkley Regional Airport (PAH) to Cape Girardeautaxi taxi
    8h 45m
    $242–722

Blue Grass Airport (LEX) to Williamson County Regional Airport (MWA) flights

Calendar21Weekly Planes
Duration6h 5mAverage Duration
Ticket$108Cheapest Price
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Questions & Answers

Map of how to get from Lexington to Cape Girardeau.ExpandLaunch map view
  • Distance: 549.7 mi
  • Duration: 12h 51m

What companies run services between Lexington, KY, USA and Cape Girardeau, MO, USA?

You can take a bus from Tates Creek @ Dove Run to Cape Girardeau via Transit Center, Walmart @ Northpark, Lexington Bus Stop, Indianapolis Union Station, St Louis Bus Station, and Cape Girardeau in around 14h 38m.

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