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How to get fromLexington to Columbiaby car, plane, bus, or train

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There are 4 ways to get from Lexington to Columbia by car, plane, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Louisville International Airport, fly

    best
    1. Drive from Lexington to Louisville-Airport-SDFcar car
    2. Fly from Louisville International Airport (SDF) to Columbia (CAE)plane plane SDF - CAE
    6h 11m
    $186–1,123

  2. Drive 404.9 mi

    cheapest
    1. Drive from Lexington to Columbiacar car 404.9 mi
    7h 51m
    $74–107

  3. Drive, bus, train (Amtrak)

    1. Drive from Lexington to Middletown Station @ Targetcar car
    2. Take the bus from Louisville, KY to Chicago Union Stationbus bus
    3. Take the train from Chicago Union Station to Columbia Stationtrain train
    39h 36m
    $474–933

  4. Fly from Blue Grass Airport

    1. Fly from Blue Grass Airport (LEX) to Columbia (CAE)plane plane LEX - CAE
    7h 38m
    $204–1,304

Louisville International Airport (SDF) to Columbia (CAE) flights

Calendar120Weekly Planes
Duration4h 41mAverage Duration
Ticket$174Cheapest Price
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Questions & Answers

Map of how to get from Lexington to Columbia.ExpandLaunch map view
  • Distance: 478 mi
  • Duration: 6h 11m

What companies run services between Lexington, KY, USA and Columbia, SC, USA?

Delta, American Airlines, and United Airlines fly from Blue Grass Airport (LEX) to Columbia (CAE) every 2 hours.

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