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How to get fromLexington to Des Moinesby car, plane, or bus

Find Transport to Des Moines

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There are 5 ways to get from Lexington to Des Moines by car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Covington, fly

    best
    1. Drive from Lexington to Covington (CVG)car car
    2. Fly from Covington (CVG) to Des Moines (DSM)plane plane CVG - DSM
    5h 12m
    $162–793

  2. Drive, bus

    cheapest
    1. Drive from Lexington to Middletown Station @ Targetcar car
    2. Take the bus from Louisville, KY to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Des Moinesbus bus
    17h 6m
    $106–208

  3. Drive 650.1 mi

    1. Drive from Lexington to Des Moinescar car 650.1 mi
    11h 17m
    $119–172

  4. Drive to Louisville International Airport, fly

    1. Drive from Lexington to Louisville-Airport-SDFcar car
    2. Fly from Louisville International Airport (SDF) to Des Moines (DSM)plane plane SDF - DSM
    5h 18m
    $161–792

  5. Fly from Blue Grass Airport

    1. Fly from Blue Grass Airport (LEX) to Des Moines (DSM)plane plane LEX - DSM
    7h 17m
    $179–873

Covington (CVG) to Des Moines (DSM) flights

Calendar132Weekly Planes
Duration4h 37mAverage Duration
Ticket$138Cheapest Price
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Questions & Answers

Map of how to get from Lexington to Des Moines.ExpandLaunch map view
  • Distance: 591.7 mi
  • Duration: 5h 12m

What companies run services between Lexington, KY, USA and Des Moines, IA, USA?

United Airlines, American Airlines, and Delta fly from Blue Grass Airport (LEX) to Des Moines (DSM) every 2 hours.

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