There are 5 ways to get from Lexington to Duke University by car, plane, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive to Covington, fly
best- Drive from Lexington to Covington (CVG)car
- Fly from Covington (CVG) to Raleigh-Durham International Airport (RDU)plane CVG - RDU
5h 3m$142–779Drive 423.5 mi
cheapest- Drive from Lexington to Duke Universitycar 423.5 mi
8h 22m$78–112Drive, bus, train
- Drive from Lexington to Middletown Station @ Targetcar
- Take the bus from Louisville, KY to Chicago Union Stationbus
- Take the train from Chicago Union Station to Raleigh Union Stationtrain
- Take the bus from Union Station - Bus Platform A to Chapel Dr at Duke University Rdbus Drx
36h 51m$617–1,036Drive to Louisville International Airport, fly
- Drive from Lexington to Louisville-Airport-SDFcar
- Fly from Louisville International Airport (SDF) to Raleigh-Durham International Airport (RDU)plane SDF - RDU
5h 2m$116–628Fly from Blue Grass Airport
- Fly from Blue Grass Airport (LEX) to Raleigh-Durham International Airport (RDU)plane LEX - RDU
8h 28m$79–469
Covington (CVG) to Raleigh-Durham International Airport (RDU) flights
Comparing Your Travel Options
The cheapest way to get from Lexington to Duke University is to drive which costs $75 - $120 and takes 8h 22m.
The fastest way to get from Lexington to Duke University is to drive and fly which takes 5h 2m and costs $110 - $650.
The distance between Lexington and Duke University is 493 miles. The road distance is 426 miles.
It takes approximately 5h 3m to get from Lexington to Duke University, including transfers.
Yes, the driving distance between Lexington to Duke University is 426 miles. It takes approximately 8h 22m to drive from Lexington to Duke University.
There are 405+ hotels available in Duke University.
What companies run services between Lexington, KY, USA and Duke University, NC, USA?
American Airlines, Delta, and United Airlines fly from Blue Grass Airport (LEX) to Raleigh-Durham International Airport (RDU) hourly.
- Website
- aa.com
Flights from Covington to Raleigh-Durham International Airport via Charlotte
- Ave. Duration
- 3h 43m
- When
- Sunday, Thursday, Monday, Wednesday, and Friday
- Estimated price
- $130–800
Flights from Louisville International Airport to Raleigh-Durham International Airport via Charlotte
- Ave. Duration
- 3h 32m
- When
- Every day
- Estimated price
- $95–600
Flights from Blue Grass Airport to Raleigh-Durham International Airport via Charlotte
- Ave. Duration
- 3h 51m
- When
- Every day
- Estimated price
- $70–460
Flights from Blue Grass Airport to Raleigh-Durham International Airport via Philadelphia
- Ave. Duration
- 4h 32m
- When
- Thursday to Sunday
- Estimated price
- $110–600
Flights from Blue Grass Airport to Raleigh-Durham International Airport via Chicago O'Hare
- Ave. Duration
- 5h 9m
- When
- Friday, Saturday, Monday, Tuesday, Thursday, and Sunday
- Estimated price
- $120–600
- Website
- delta.com
Flights from Covington to Raleigh-Durham International Airport
- Ave. Duration
- 1h 28m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–750
Flights from Blue Grass Airport to Raleigh-Durham International Airport via Atlanta
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- $95–550
Flights from Blue Grass Airport to Raleigh-Durham International Airport via Detroit
- Ave. Duration
- 4h 53m
- When
- Every day
- Estimated price
- $100–600
- Website
- southwest.com
Flights from Covington to Raleigh-Durham International Airport via Nashville
- Ave. Duration
- 3h 37m
- When
- Saturday to Friday
- Estimated price
- $150–900
Flights from Covington to Raleigh-Durham International Airport via Baltimore
- Ave. Duration
- 3h 40m
- When
- Tuesday, Wednesday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $150–900
Flights from Louisville International Airport to Raleigh-Durham International Airport via Nashville
- Ave. Duration
- 3h 20m
- When
- Monday
- Estimated price
- $100–650
Flights from Louisville International Airport to Raleigh-Durham International Airport via Baltimore
- Ave. Duration
- 3h 45m
- When
- Monday, Thursday, and Friday
- Estimated price
- $120–700
- Website
- united.com
Flights from Blue Grass Airport to Raleigh-Durham International Airport via Chicago O'Hare
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- $120–600
- Website
- flybreeze.com
Flights from Louisville International Airport to Raleigh-Durham International Airport
- Ave. Duration
- 1h 26m
- When
- Wednesday and Saturday
- Estimated price
- $220–1,400
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Raleigh Union Station
- Ave. Duration
- 24h 1m
- Frequency
- Once daily
- Estimated price
- $550–950
- Website
- Amtrak
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Louisville, KY to Chicago Union Station
- Ave. Duration
- 6h
- Frequency
- Twice daily
- Estimated price
- $50–60
- Website
- Amtrak
- Adult
- $50–60
- Phone
- +1 919 485 7433
- [email protected]
- Website
- gotriangle.org
Bus from Union Station - Bus Platform A to Chapel Dr at Duke University Rd
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- $3
- Website
- gotriangle.org
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide




